Microcrystalline cellulose
Synonym(s):Cellulose;Cellulose microcrystalline;Cellulose powder;Cellulosum microcristallinum;Cotton linters
- CAS NO.:9004-34-6
- Empirical Formula: (C12H20O10)n
- Molecular Weight: 324.28
- MDL number: MFCD00081512
- EINECS: 232-674-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-11 20:10:50
What is Microcrystalline cellulose?
The Uses of Microcrystalline cellulose
Microcrystalline Cellulose is a gum that is the nonfibrous form of cellulose, an alpha-cellulose. It is dispersible in water but not soluble, requiring considerable energy to disperse and hydrate. In this form it is used in dry applications such as tableting, capsules, and shredded cheese where it functions as a non-nutritive filler, binder, flow aid, and anticaking agent. By the addition of carboxymethylcellulose to the alpha-cellulose prior to drying, improved functional properties of hydration and dispersion are obtained. This product is designed for use in water dispersions, being insoluble in water but dispersing in water to form colloidal sols below 1% and white opaque gels above the 1% usage level. It is used as a heat shock stabilizer and bodying agent in frozen desserts, as an opacifier in low-fat dressings, as a foam stabilizer in whipped toppings, and as an emulsifier in dressings. Also termed cellulose gel.
Property
Chemically, microcrystalline cellulose is an inert substance, is not degraded during digestion and has no appreciable absorption. In large quantities it provides dietary bulk and may lead to a laxative effect.
Pharmaceutical Excipient
Microcrystalline cellulose is a commonly used excipient in the pharmaceutical industry. It has excellent compressibility properties and is used in solid dose forms, such as tablets. Tablets can be formed that are hard, but dissolve quickly. Microcrystalline cellulose is the same as cellulose, except that it meets USP standards.
Properties of Microcrystalline cellulose
Melting point: | 76-78 °C(Solv: acetone (67-64-1); chloroform (67-66-3)) |
Density | 1.5 g/cm3 (20℃) |
Flash point: | 164 °C |
storage temp. | room temp |
solubility | Practically insoluble in water, in acetone, in anhydrous ethanol, in toluene, in dilute acids and in a 50 g/L solution of sodium hydroxide |
form | powder |
color | White or almost white |
Odor | Odorless |
Water Solubility | insoluble |
Safety information for Microcrystalline cellulose
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. |
Computed Descriptors for Microcrystalline cellulose
InChIKey | UFHFLCQGNIYNRP-UHFFFAOYSA-N |
Abamectin manufacturer
Krishkan Chemicals
HRV Global Life Sciences
Ankit Pulps and Boards Pvt. Ltd. APB
Vasa Pharmachem Pvt Ltd
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