Maleic acid
Synonym(s):Butenedioic Acid;Toxilic acid;(2Z)-2-Butenedioic acid;(2Z)-But-2-enedioic acid;cis-Butenedioic acid
- CAS NO.：110-16-7
- Empirical Formula: C4H4O4
- Molecular Weight: 116.07
- MDL number: MFCD00063177
- EINECS: 203-742-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-10 14:01:29
What is Maleic acid?
Description
Maleic acid is an organic compound that is a dicarboxylic acid, a molecule with two carboxyl groups. Its chemical formula is HO2CCHCHCO2H. Maleic acid is the cis-isomer of butenedioic acid, where as fumaric acid is the trans-isomer. It is mainly used as a precursor to fumaric acid, and relative to its parent maleic anhydride, maleic acid has few applications.
The Uses of Maleic acid
Maleic acid is used as a precursor to fumaric acid, dimethyl maleate and glyoxalic acid. It is an electrophile and acts as dienophine in Diels-Alder reactions. It reacts with drugs to form more stable addition salts like indacaterol maleate, carfenazine, chlorpheniramine, pyrilamine, methylergonovine and thiethylperazine. Its maleate ion is useful in biochemistry as an inhibitor of transaminase reactions.
Properties of Maleic acid
| Melting point: | 130-135 °C (lit.) |
| Boiling point: | 275°C |
| Density | 1.59 g/mL at 25 °C (lit.) |
| Flash point: | 127 °C |
| storage temp. | Store below +30°C. |
| solubility | 478.8g/l |
| form | Powder/Solid |
| color | White |
| Water Solubility | 790 g/L (25 ºC) |
Safety information for Maleic acid
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H317:Sensitisation, Skin H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Maleic acid
| InChIKey | VZCYOOQTPOCHFL-OWOJBTEDSA-N |
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