L-Methionine
Synonym(s):L-Methionine;Met;L-Methionine - CAS 63-68-3 - Calbiochem;(S)-2-Amino-4-(methylmercapto)butyric acid;L -2-Amino-4-(methylthio)butanoic acid
- CAS NO.:63-68-3
- Empirical Formula: C5H11NO2S
- Molecular Weight: 149.21
- MDL number: MFCD00063097
- EINECS: 200-562-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-16 14:11:51
What is L-Methionine?
Absorption
Absorbed from the lumen of the small intestine into the enterocytes by an active transport process.
Toxicity
Doses of L-methionine of up to 250 mg daily are generally well tolerated. Higher doses may cause nausea, vomiting and headache. Healthy adults taking 8 grams of L-methionine daily for four days were found to have reduced serum folate levels and leucocytosis. Healthy adults taking 13.9 grams of L-methionine daily for five days were found to have changes in serum pH and potassium and increased urinary calcium excretion. Schizophrenic patients given 10 to 20 grams of L-methionine daily for two weeks developed functional psychoses. Single doses of 8 grams precipitated encephalopathy in patients with cirrhosis.
Description
Colorless or white lustrous plates, or a white crystalline powder. It has a slight, characteristic odor. It is soluble in water, in alkali solutions, and in dilute mineral acids. It is slightly soluble in alcohol and practically insoluble in ether.
The Uses of L-Methionine
L-Methionine is used as an essential amino acid for human development and therapeutically acts as an antidote for acetaminophen poisoning. It serves as a chelating agent for heavy metals, as a flavoring agent and nutritional supplement for foods. It acts as a feed additive, vegetable oil enrichment and as a single cell protein. In addition to this, it is used as a hepatoprotectant and also acts as a lipotropic agent and prevents excess fat buildup in the liver.
Indications
Used for protein synthesis including the formation of SAMe, L-homocysteine, L-cysteine, taurine, and sulfate.
Background
A sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals.
What are the applications of Application
L-Methionine is an essential amino acid
Pharmacokinetics
L-Methionine is a principle supplier of sulfur which prevents disorders of the hair, skin and nails; helps lower cholesterol levels by increasing the liver's production of lecithin; reduces liver fat and protects the kidneys; a natural chelating agent for heavy metals; regulates the formation of ammonia and creates ammonia-free urine which reduces bladder irritation; influences hair follicles and promotes hair growth. L-methionine may protect against the toxic effects of hepatotoxins, such as acetaminophen. Methionine may have antioxidant activity.
Metabolism
Hepatic
Properties of L-Methionine
Melting point: | 284 °C (dec.)(lit.) |
Boiling point: | 393.91°C (estimate) |
Density | 1,34g/cm |
storage temp. | 20-25°C |
solubility | 1 M HCl: 0.5 M at 20 °C, clear, colorless |
form | Solid |
color | White |
Water Solubility | Soluble |
Safety information for L-Methionine
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. |
Computed Descriptors for L-Methionine
Abamectin manufacturer
JSK Chemicals
HRV Global Life Sciences
Meteoric Biopharmaceuticals Pvt. Ltd.
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