Kaempferol

Synonym(s):3,4ʹ,5,7-Tetrahydroxyflavone;3,4′,5,7-Tetrahydroxyflavone;3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;Kaempferol - CAS 520-18-3 - Calbiochem;Robigenin

CAS NO.：520-18-3
Empirical Formula: C15H10O6
Molecular Weight: 286.24
MDL number: MFCD00016938
EINECS: 208-287-6
SAFETY DATA SHEET (SDS)
Update Date: 2024-05-15 13:45:27

What is Kaempferol?

Description

The flavonoid kaempferol takes its name from one of its sources, aromatic ginger (Kaempferia galanga). It was isolated from forking larkspur (Delphinium consolida?L.) by A. G. Perkin and E. J. Wilkinson in 1902. Since then, it has been found in plants such as grapefruit, tea, broccoli, witch hazel, and apple. Studies on kaempferol show that taking it may lower the risk of contracting pancreatic and lung cancer.

The Uses of Kaempferol

Kaempferol, is used as an inhibitor of Fatty Acid Synthase, Cox-1 activity, and Topo I. It also Induces caspase-9-mediated apoptosis in a variety of cancer cell lines via downregulation of polo-like kinase 1 (PLK1) expression. Exhibits antioxidant activity and attenuates osteoclastic bone reabsorption in vitro. Also blocks EGF-induced histone H3Ser10 phosphorylation in mouse epidermal JB6 C141 cells.

What are the applications of Application

Kaempferol is an inhibitor of Fatty Acid Synthase, COX-1 activity, and Topo I

Properties of Kaempferol

Melting point:	276°C
Boiling point:	348.61°C (rough estimate)
Density	1.2981 (rough estimate)
storage temp.	2-8°C
solubility	ethanol: 20 mg/mL
form	powder
color	yellow

Safety information for Kaempferol

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..…