Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
HomeProduct name listIguratimod

Iguratimod

Synonym(s):3-Formylamino-7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-one;IGU;N-(7-(Methylsulfonamido)-4-oxo-6-phenoxy-4H-chromen-3-yl)formamide;N-[3-(Formylamino)-4-oxo-6-phenoxy-4H-1-benzopyran-7-yl]methanesulfonamide;T-614

  • CAS NO.:123663-49-0
  • Empirical Formula: C17H14N2O6S
  • Molecular Weight: 374.37
  • MDL number: MFCD00882374
  • EINECS: 808-127-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-04-25 13:42:50
Iguratimod Structural Picture

What is Iguratimod?

Description

In August 2011, China’s State FDA approved Simcere Pharmaceutical Group’s new drug application for iguratimod (T-614), a disease modifying anti-rheumatic drug (DMARD) for the treatment of rheumatoid arthritis (RA). Preclinical in vivo studies indicated that iguratimod was effective in an established adjuvant-induced arthritis model (ED40=3.6 mg/kg) in rats and also efficacious in a type II collagen-induced arthritis model in DBA/1J mice at 30 mg and 100 mg/kg.

The Uses of Iguratimod

Iguratimod acts as an anti-inflammatory agent, used primarily in the treatment of rheumatoid arthritis.

Properties of Iguratimod

Melting point: 238.0 to 242.0 °C
Boiling point: 580.6±60.0 °C(Predicted)
Density  1.52±0.1 g/cm3(Predicted)
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
solubility  DMSO (Slightly)
form  Solid
color  White to Off-White

Safety information for Iguratimod

Signal word Warning
Pictogram(s)

Health Hazard
GHS08
GHS Hazard Statements H361:Reproductive toxicity
Precautionary Statement Codes P201:Obtain special instructions before use.
P202:Do not handle until all safety precautions have been read and understood.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313:IF exposed or concerned: Get medical advice/attention.
P405:Store locked up.

Computed Descriptors for Iguratimod

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.