Glycitein

Synonym(s):4′,7-Dihydroxy-6-methoxyisoflavone;Glycetein

CAS NO.：40957-83-3
Empirical Formula: C16H12O5
Molecular Weight: 284.26
MDL number: MFCD00016679
SAFETY DATA SHEET (SDS)
Update Date: 2024-03-29 18:52:01

What is Glycitein?

Description

Glycitein is an O-methylated isoflavone that comprises 5-10% of the total isoflavones in soy food products. This phytoestrogen is reported to have weak estrogenic activity, displacing estradiol binding at the estrogen receptor in vitro with an IC₅₀ value of 3.94 μM. It suppresses the proliferation of osteoblasts and promotes differentiation from its progenitor. It has also been used to attenuate proliferation (10 μM) of aortic smooth muscle cells related to atherosclerotic vascular change in stroke-prone hypertensive rats and to protect against beta amyloid (Aβ)-induced toxicity and oxidative stress (100 μg/ml) in C. elegans expressing human Aβ.

The Uses of Glycitein

Glycitein may be used as a reference standard in the determination of glycitein in hydrolyzed dry soya extracts using reversed-phase high-performance liquid chromatography (RP-HPLC).

What are the applications of Application

Glycitein is a soybean isoflavonoid

Properties of Glycitein

Melting point:	>300°C
Boiling point:	547.4±50.0 °C(Predicted)
Density	1.420±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	Aqueous Base (Slightly), DMSO (Slightly)
form	Solid
color	Light Brown

Safety information for Glycitein

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H301:Acute toxicity,oral H311:Acute toxicity,dermal H314:Skin corrosion/irritation H331:Acute toxicity,inhalation
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P302+P352:IF ON SKIN: wash with plenty of soap and water. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..…