Diazomethane
- CAS NO.：334-88-3
- Empirical Formula: CH2N2
- Molecular Weight: 42.03998
- EINECS: 206-382-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-03-14 15:18:26
What is Diazomethane?
Description
Diazomethane is a reagent typically used to methylate various functional groups such as carboxylic acids, alcohols, phenols, and amides. The most common use of diazomethane is to convert carboxylic acids to esters. Diazomethane is usually prepared from the decomposition of a N-methyl-N-nitrosoamines such as Diazald. Diazomethane is highly toxic and can detonate unexpectedly, thus should be handled with care.
The Uses of Diazomethane
Powerful methylating agent for acidic Compounds such as carboxylic acids, phenols, enols. For syntheses with diazomethane see the reviews by Smith, Chem. Rev. 23, 193 (1938); Eistert, Z. Angew. Chem. 54, 99, 124 (1941) translated by Spangler in Newer Methods of Preparative Organic Chemistry (New York, 1948) p 513; J. S. Pizey, Synthetic Reagents vol. 2 (John Wiley, New York, 1974) pp 65-142.
Properties of Diazomethane
| Melting point: | -145° |
| Boiling point: | bp -23° |
| Density | 1.45 g/cm3 |
| form | Yellow gas |
| appearance | Yellow gas |
| Odor | Musty odor (no accepted threshold value) |
Safety information for Diazomethane
Computed Descriptors for Diazomethane
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