CORTISONE
- CAS NO.：53-06-5
- Empirical Formula: C21H28O5
- Molecular Weight: 360.44
- MDL number: MFCD00003610
- EINECS: 200-162-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-09-25 13:50:22
What is CORTISONE?
Description
Cortisone (shown) and its close cousin prednisone (with an additional double bond) are widely used anti-inflammatory agents, but their use must be monitored carefully because they can suppress the immune system. Cortisone was identified in the 1930s by Edward C. Kendall at the Mayo Clinic, who shared the 1950 Nobel Prize for physiology or medicine for his work. Prednisone was developed in the 1950s by Arthur Nobile and co-workers at Schering.
The Uses of CORTISONE
Cortisone is used for inflammatory processes, allergies, and adrenal insufficiency.
What are the applications of Application
Cortisone is a glucocorticoid, anti-inflammatory agent.
Properties of CORTISONE
| Melting point: | 223-228 °C (dec.)(lit.) |
| Boiling point: | 412.46°C (rough estimate) |
| Density | 1.28±0.1 g/cm3 (20 ºC 760 Torr) |
| Flash point: | 9℃ |
| storage temp. | -20°C Freezer |
| solubility | Chloroform (Slightly, Heated, Sonicated), DMSO (Slightly), Ethanol (Slightly, He |
| form | Solid |
| color | White to Pale Beige |
| Water Solubility | 229.9mg/L(25 ºC) |
Safety information for CORTISONE
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H225:Flammable liquids H370:Specific target organ toxicity, single exposure |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P311:Call a POISON CENTER or doctor/physician. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for CORTISONE
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