Benzyl alcohol

Toxicity

1250 mg/kg (rat, oral) LD50 400 mg/kg IPR-RAT LD50 2000 mg/kg SKN-RBT LD50 53 mg/kg IVN-RAT LD50 2500 mg/kg ORL-GPG LD50

Description

Benzyl alcohol is a component catalyst for epoxy resins. It is also contained in the color developer C-22.

Description

Benzyl alcohol is generally used as a reagent in organic chemistry, although in some other industries it finds common use as a solvent.

The Uses of Benzyl alcohol

benzyl alcohol is a preservative against bacteria, used in concentrations of 1 to 3 percent. It can cause skin irritation.

The Uses of Benzyl alcohol

To a solution of the alcohol (A) (86 mg, 482 umol) in anhydrous THF (5 mL) at RT was added NaH (60% dispersion on mineral oil, 21 mg, 526 umol), and the mixture was stirred at RT for 15 min. The aryl chloride (B) (150 mg, 439 umol) was added and the reaction mixture was stirred at RT for 45 min, then 80 C for 2 h. H2O and sat aq NaHCO3 were added and the mixture was extracted with EtOAc, washed with brine, dried (Na2SO4), and concentrated. The resulting material was purified by silica gel column chromatography (0-25% EtOAc/cyclohexane) to provide the product. [137 mg]

Indications

Ulesfia (benzyl alcohol) lotion is indicated for the topical treatment of head lice infestation in patients 6 months of age and older. Ulesfia Lotion does not have ovicidal activity.

Metabolism

Not Available