5-Hydroxymethylfurfural

Synonym(s):HMF;5-Hydroxymethyl-2-furaldehyde;5-(Hydroxymethyl)furfural;5-Hydroxymethyl-2-furancarboxaldehyde;5-Hydroxymethyl-2-furancarbaldehyde

CAS NO.：67-47-0
Empirical Formula: C6H6O3
Molecular Weight: 126.11
MDL number: MFCD00003234
EINECS: 200-654-9
SAFETY DATA SHEET (SDS)
Update Date: 2024-05-28 19:59:05

5-Hydroxymethylfurfural Structural Picture

What is 5-Hydroxymethylfurfural?

Description

5-Hydroxymethylfurfural (5-HMF) derived from sugars is the link between biomass and furan-based chemicals. With its various functional groups and associated reaction sites, this small molecule opens the door to a wide range of chemical modifications, which makes 5-HMF a versatile renewable building block.
5-HMF is widely spread in food products and is formed in sugar containing food when exposed to heat. It is widely used as an indicator of quality in food products. It is also employed to indicate the adulteration of food products with acid converted invert syrups.

Description

5-(Hydroxymethyl)furfural (HMF) is derived by dehydrating sugars, fructose in particular. It was first synthesized from fructose by W. N. Haworth and W. G. M. Jones in 1944. It has been used as a starting material to synthesize compounds with oxygen-containing functional groups; HMF-derived 2,5-dimethyfuran has been evaluated as a biofuel.?Recently, HMF was shown to be toxic to honeybees fed with high-fructose corn syrup.

The Uses of 5-Hydroxymethylfurfural

5-Hydroxymethylfurfural is a chemical substance produced by dehydration of glucose or fructose. The molecule contains a furan ring, an aldehyde group and a hydroxymethyl group. The chemical properties are relatively lively. 5-Hydroxymethylfurfural can prepare various derivatives through oxidation, hydrogenation and condensation, and is an important fine chemical raw material.
5-Hydroxymethylfurfural is a furfural compound with a furan ring structure produced by dehydration of monosaccharide compounds such as glucose under high temperature or weak acid conditions. It is an endogenous pollutant with potential safety hazards. 5-Hydroxymethylfurfural is an important chemical raw material. Its molecule contains an aldehyde group and a hydroxymethyl group, which can be used to synthesize many useful compounds and new polymer materials through hydrogenation, oxidative dehydrogenation, esterification, halogenation, polymerization, hydrolysis and other chemical reactions, including Medicine, resin-based plastics, diesel fuel additives, etc.

What are the applications of Application

5-Hydroxymethyl-2-furaldehyde is an antioxidant found in some fruit juices

Properties of 5-Hydroxymethylfurfural

Melting point:	28-34 °C (lit.) 28-34 °C (lit.)
Boiling point:	114-116 °C/1 mmHg (lit.)
Density	1.243 g/mL at 25 °C (lit.)
Flash point:	175 °F
storage temp.	2-8°C
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form	Liquid or Crystalline Powder and/or Chunks
color	Light yellow to yellow
Water Solubility	Soluble in water, alcohol, ethyl acetate, acetone, dimethylformamide, benzene, ether and chloroform.
Sensitive	Air & Light Sensitive

Safety information for 5-Hydroxymethylfurfural

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention.