3-Chloroperoxybenzoic acid

Description

m-CPBA is a peroxycarboxylic acid that is commonly used as an oxidizing agent. It is usually available in <77% form because pure m-CPBA is shock sensitive (potentially explosive). It usually consists of ~10% m-chlorobenzoic acid and the remainder is H2O.

The Uses of 3-Chloroperoxybenzoic acid

3-Chloroperoxybenzoic acid is a strong oxidizing agent used in the oxidation reactions such as aldehydes and ketones to esters (Bayer-Villiger-Oxidation), olefines to epoxides, sulfides to sulfoxides and sulfones, and amines to nitroalkanes, N-oxides.

The Uses of 3-Chloroperoxybenzoic acid

The SM (1 g, 3 mmol) was suspended in acetone (10 mL), cooled to 0 C, and treated portionwise with mCPBA (2.59 g, 15 mmol). The suspension became a clear solution after stirring at 0 C for 30 min. The reaction mixture was then allowed to warm up slowly to RT and was stirred for 5 h. Saturated aq NaHCO3 (50 mL) was added to give a mixture with pH 8. The resulting mixture was extracted with EtOAc (3 x 10 mL). The combined organics were washed with brine, dried (Na2SO4), and concentrated to provide crude product. [1 g]

What are the applications of Application

3-Chloroperbenzoic acid is a reagent for the epoxidation of olefins