36791-04-5
Product Name:
Ribavirin
Formula:
C8H12N4O5
Synonyms:
1-β-D -Ribofuranosyl-1,2,4-triazole-3-carboxamide;1-β-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide, Virazole;Ribavirin;Ribavirin - CAS 36791-04-5 - Calbiochem
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Ribavirin is a white powder. Exists in two polymorphic forms. (NTP, 1992) |
|---|---|
| Color/Form | Colorless |
| Odor | Odorless |
| Taste | Tasteless |
| Melting Point | 345 to 349 °F (NTP, 1992) |
| Solubility | greater than or equal to 100 mg/mL at 66 °F (NTP, 1992) |
| LogP | -1.85 |
| Stability/Shelf Life | Ribavirin solutions contain no preservatives and are stable for 24 hr when stored under sterile conditions at a room temperature of 20-30 °C. Following addition of the reconstituted solution to the reservoir of the SPAG-2 and further dilution with sterile water for injection or inhalation (additive free), the ribavirin solution for nebulization should be discarded within 24 hr. |
| Optical Rotation | Specific optical rotation: -36.5 deg at 25 °C/D |
| Decomposition | When heated to decomposition it emits toxic fumes of /nitrogen oxides/. |
| Other Experimental Properties | Exists in two polymorphic forms |
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H341:Germ cell mutagenicity |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P308+P313:IF exposed or concerned: Get medical advice/attention. |
COMPUTED DESCRIPTORS
| Molecular Weight | 244.20 g/mol |
|---|---|
| XLogP3 | -1.8 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 3 |
| Exact Mass | 244.08076950 g/mol |
| Monoisotopic Mass | 244.08076950 g/mol |
| Topological Polar Surface Area | 144 Ų |
| Heavy Atom Count | 17 |
| Formal Charge | 0 |
| Complexity | 304 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 4 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Ribavirin is a white powder. Exists in two polymorphic forms. (NTP, 1992)