Nitroxylene SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Nitroxylene
- CAS： 25168-04-1
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
no data available
GHS label elements, including precautionary statements
- Signal word no data available
no data available
no data available
no data available
no data available
no data available
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Nitroxylene
- Common names and synonyms: Nitroxylene
- CAS number: 25168-04-1
- EC number: 246-697-7
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
Rinse with pure water for at least 15 minutes. Consult a doctor.
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Most important symptoms/effects, acute and delayed
SYMPTOMS: Symptoms of exposure to this compound may include irritation of the skin, eyes, mucous membranes and upper respiratory tract and cyanosis. Similar chemicals cause methemoglobinemia. ACUTE/CHRONIC HAZARDS: This compound may be fatal if inhaled, swallowed or absorbed through the skin. Vapor or mist is irritating to the eyes, skin, mucous membranes and upper respiratory tract. When heated to decomposition this compound may emit toxic fumes of carbon monoxide, carbon dioxide and oxides of nitrogen. (NTP, 1992)
Indication of immediate medical attention and special treatment needed, if necessary
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Poisons A and B
SECTION 5: Firefighting measures
Suitable extinguishing media
Fires involving this material can be controlled with a dry chemical, carbon dioxide, or Halon extinguisher. A water spray may also be used. (NTP, 1992)
Specific hazards arising from the chemical
This chemical is combustible. (NTP, 1992)
Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.
Environmental precautions
Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
SECTION 7: Handling and storage
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
SECTION 8: Exposure controls/personal protection
Control parameters
no data available
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
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Physical state：
PHYSICAL DESCRIPTION: Yellow liquid. (NTP, 1992)
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Colour：
Pale yellow oil
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Odour：
no data available
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Melting point/freezing point：
45 to 48° F (NTP, 1992)
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Boiling point or initial boiling point and boiling range：
243.3°C at 760mmHg
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Flammability：
no data available
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Lower and upper explosion limit/flammability limit：
no data available
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Flash point：
107.8°C
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Auto-ignition temperature：
no data available
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Decomposition temperature：
no data available
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pH：
no data available
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Kinematic viscosity：
no data available
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Solubility：
less than 1 mg/mL at 70° F (NTP, 1992)
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Partition coefficient n-octanol/water：
log Kow = 2.83
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Vapour pressure：
0.0503mmHg at 25°C
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Density and/or relative density：
1.129g/cm3
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Relative vapour density：
5.22 (NTP, 1992) (Relative to Air)
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Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
no data available
Chemical stability
no data available
Possibility of hazardous reactions
1,2-DIMETHYL-3-NITROBENZENE is incompatible with strong oxidizers and strong bases (NTP, 1992).
Conditions to avoid
no data available
Incompatible materials
no data available
Hazardous decomposition products
no data available
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral (female) 2110 mg/kg body weight
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: no data available
- Toxicity to daphnia and other aquatic invertebrates: LC50; Species: Daphnia magna (Waterflea) age <24 hr; Conditions: freshwater, static, 20 deg C, pH 8.2, hardness 250 mg/L CaCO3, dissolved oxygen >6.5 mg/L; Concentration: 4200 ug/L for 48 hr (95% confidence interval: 3200-5600 ug/L) /formulation
- Toxicity to algae: EC50; Species: Chlorella pyrenoidosa (Green Algae) exponential growth phase, 2 X10+8 cells/mL; Conditions: freshwater, static, 25 deg C, pH 6.6; Concentration: 6300 ug/L for 96 hr (95% confidence interval: 4100-9800 ug/L); Effect: population changes, general /formulation
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: 1,2-Dimethyl-3-nitrobenzene, present at 100 mg/L, reached 0% of its theoretical BOD in 4 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test (OECD TG 301C) that suggests the compound is not readily biodegradable(1). This Japanese MITI test yields similar results for 2-methylnitrobenzene and 4-methylnitrobenzene(1); however, other biodegradation screening tests have shown that biodegradation of these compounds in acclimated media (activated sludge, soil, water) can be relatively fast with 98-100% degradation within a few days to few weeks(2-4).
Bioaccumulative potential
A log BCF of 2.86 (BCF = 724) for 1,2-dimethyl-3-nitrobenzene was measured in guppies (Poecilla reticulata) during a 3-day static-flow test, measurement based on a fat-weight basis(1). According to a classification scheme(2), this log BCF suggests bioconcentration in aquatic organisms is high(SRC).
Mobility in soil
Using a structure estimation method based on molecular connectivity indices(1), the Koc of 1,2-dimethyl-3-nitrobenzene can be estimated to be 606(SRC). According to a classification scheme(2), this estimated Koc value suggests that 1,2-dimethyl-3-nitrobenzene is expected to have low mobility in soil.
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: no data available
IMDG: no data available
IATA: no data available
UN Proper Shipping Name
ADR/RID: no data available
IMDG: no data available
IATA: no data available
Transport hazard class(es)
ADR/RID: no data available
IMDG: no data available
IATA: no data available
Packing group, if applicable
ADR/RID: no data available
IMDG: no data available
IATA: no data available
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/