Propyl nitrate SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Propyl nitrate
- CAS： 627-13-4
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
no data available
GHS label elements, including precautionary statements
- Signal word no data available
no data available
no data available
no data available
no data available
no data available
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Propyl nitrate
- Common names and synonyms: Propyl nitrate
- CAS number: 627-13-4
- EC number: 210-985-0
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Artificial respiration may be needed. Refer for medical attention. See Notes.
Rinse and then wash skin with water and soap.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Refer for medical attention .
Most important symptoms/effects, acute and delayed
Exposure can cause anoxia and cyanosis. Other effects are weakness, dizziness, and severe headaches. (USCG, 1999)
Indication of immediate medical attention and special treatment needed, if necessary
Maintain an open air way and assist ventilations if necessary. Administer supplemental oxygen. Treat hypotension with supine positioning, intravenous crystalloid fluids. and low-dose pressors if needed.Monitor vital signs and ECG for 4 to 6 hours. Symptomatic methemoglobinemia may be treated with methylene blue. Hemodialysis and hemoperfusion are not effective. Sever methemoglobinemia in infants not responsive to methylene blue therapy may require exchange transfusion.
SECTION 5: Firefighting measures
Suitable extinguishing media
Use dry chemical, foam, carbon dioxide, or water spray. Water may be ineffective. Use water spray to keep fire-exposed containers cool. Fight fire from protected location or maximum possible distance.
Specific hazards arising from the chemical
Special Hazards of Combustion Products: Toxic gases and vapors, such as oxides of nitrogen and carbon monoxide, may be released in a fire. (USCG, 1999)
Special protective actions for fire-fighters
Use water spray, powder, alcohol-resistant foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water. Combat fire from a sheltered position.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Remove all ignition sources. Personal protection: self-contained breathing apparatus. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer.
Environmental precautions
Remove all ignition sources. Personal protection: self-contained breathing apparatus. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer.
Methods and materials for containment and cleaning up
Eliminate all ignition sources. Stop or control the leak, if this can be done without undue risk. Use appropriate foam to blanket release and suppress vapors. Absorb in noncombustible material for proper disposal.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames, NO sparks and NO smoking. NO contact with oxidizing agents, combustible substances or reducing agents. Do NOT expose to friction or shock. Closed system, ventilation, explosion-proof electrical equipment and lighting. Use non-sparking handtools. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Well closed. Cool. Fireproof. Separated from strong oxidants, combustible substances and reducing agents.
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 25 ppm as TWA; 40 ppm as STEL; BEI issued
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety goggles.
Protective gloves.
Use ventilation, local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
N-propyl nitrate is a white to straw-colored liquid with an ether-like odor. About the same density as water and insoluble in water. Flash point 70°F. Vapors heavier than air. Used as a fuel. Shock sensitive. The shock sensitivity is removed by addition of 1-2% of propane, butane, chloroform, ethyl ether, or methyl ether.
-
Colour：
Pale yellow liquid
-
Odour：
Sweet sickly odor
-
Melting point/freezing point：
-100°C
-
Boiling point or initial boiling point and boiling range：
110.5°C
-
Flammability：
Class IB Flammable Liquid: Fl.P. below 73°F and BP at or above 100°F.
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
68° F (USCG, 1999)
-
Auto-ignition temperature：
347° F (USCG, 1999)
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
no data available
-
Solubility：
Slight (NIOSH, 2016)
-
Partition coefficient n-octanol/water：
log Kow = 1.74 /Estimated/
-
Vapour pressure：
18 mm Hg (NIOSH, 2016)
-
Density and/or relative density：
1.05
-
Relative vapour density：
(air = 1): 3.6
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Heating may cause violent combustion or explosion. May decompose explosively on shock, friction or concussion. Decomposes on burning. This produces nitrogen oxides. The substance is a strong oxidant. It reacts violently with combustible and reducing materials. Reacts violently with strong oxidants.
Chemical stability
The shock-sensitive nitrate is desensitised by 1-2% of propane, butane, chloroform, dimethyl ether or diethyl ether.
Possibility of hazardous reactions
It is... flammable, and poses a dangerous fire and explosion risk.The vapour is heavier than air and may travel along the ground; distant ignition possible.Organonitrates, such as N-PROPYL NITRATE, range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction that culminates in a detonation. Nitroalkanes are milder oxidizing agents, but still react violently with reducing agents at higher temperature and pressures. Nitroalkanes react with inorganic bases to form explosive salts. The presence of metal oxides increases the thermal sensitivity of nitroalkanes. Nitroalkanes with more than one nitro group are generally explosive. Contact with either strong oxidizers or with combustibles may cause fires and explosions.
Conditions to avoid
no data available
Incompatible materials
It is considered a strong oxidizing agent.
Hazardous decomposition products
Combustion by-products may include oxides of nitrogen.
SECTION 11: Toxicological information
Acute toxicity
- Oral: no data available
- Inhalation: LC50 Rat inhalation 9,000-10,000 ppm/4 hr
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the respiratory tract, eyes and skin. Inhalation of high concentrations may cause effects on the blood. This may result in the formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. See Notes.
STOT-repeated exposure
no data available
Aspiration hazard
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: no data available
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
No data were located regarding the biodegradation of n-propyl nitrate or other low molecular weight alkyl nitrates(SRC). Nitroglycerin (1,2,3-propanetriol, trinitrate) was completely biodegraded in 13 days using river water and river water/sediment microcosms obtained from a river near a munitions facility in Virginia(1). Nitroglycerin was also biodegraded about 53% in five days using an activated sludge inoculum in a shake flask test that was run at 30 deg C(2). These results suggest that alkyl nitrates may undergo biodegradation under acclimated conditions(SRC).
Bioaccumulative potential
An estimated BCF of 5 was calculated for n-propyl nitrate(SRC), using a measured water solubility of 3,290 mg/L(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
The Koc for n-propyl nitrate can be estimated to be 40(SRC)using a measured water solubility of 3,290 mg/L(1) and a regression-derived equation(2) According to a classification scheme(3), this estimated Koc value suggests that n-propyl nitrate is expected to have very high mobility in soil(SRC).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN1865 (For reference only, please check.)
IMDG: UN1865 (For reference only, please check.)
IATA: UN1865 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: n-PROPYL NITRATE (For reference only, please check.)
IMDG: n-PROPYL NITRATE (For reference only, please check.)
IATA: n-PROPYL NITRATE (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 3 (For reference only, please check.)
IMDG: 3 (For reference only, please check.)
IATA: 3 (For reference only, please check.)
Packing group, if applicable
ADR/RID: II (For reference only, please check.)
IMDG: II (For reference only, please check.)
IATA: II (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Combustion in a confined space may turn into detonation.Depending on the degree of exposure, periodic medical examination is suggested.Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.