Trifluoroacetic acid SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Trifluoroacetic acid
- CAS： 76-05-1
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Skin corrosion, Sub-category 1A
Acute toxicity - Category 4, Inhalation
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Danger
H314 Causes severe skin burns and eye damage
H332 Harmful if inhaled
H412 Harmful to aquatic life with long lasting effects
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P363 Wash contaminated clothing before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316 Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P317 Get medical help.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Trifluoroacetic acid
- Common names and synonyms: Trifluoroacetic acid
- CAS number: 76-05-1
- EC number: 200-929-3
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Half-upright position. Refer immediately for medical attention.
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer immediately for medical attention.
Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Refer immediately for medical attention.
Rinse mouth. Do NOT induce vomiting. Refer immediately for medical attention.
Most important symptoms/effects, acute and delayed
no data available
Indication of immediate medical attention and special treatment needed, if necessary
no data available
SECTION 5: Firefighting measures
Suitable extinguishing media
Use dry chemical, carbon dioxide or alcohol-resistant foam.
Specific hazards arising from the chemical
Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.
Special protective actions for fire-fighters
In case of fire in the surroundings, use appropriate extinguishing media. In case of fire: keep drums, etc., cool by spraying with water.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: gas-tight chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable plastic containers. Absorb remaining liquid in sand or inert absorbent. Carefully collect remainder. Then store and dispose of according to local regulations.
Environmental precautions
Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
SECTION 7: Handling and storage
Precautions for safe handling
NO contact with bases, oxidizing agents or reducing agents. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Separated from strong bases, metals, oxidants and food and feedstuffs. Keep in a well-ventilated room. Store in an area without drain or sewer access.
SECTION 8: Exposure controls/personal protection
Control parameters
| Component | Trifluoroacetic acid | |||
|---|---|---|---|---|
| CAS No. | 76-05-1 | |||
| Limit value - Eight hours | Limit value - Short term | |||
| ppm | mg/m3 | ppm | mg/m3 | |
| Latvia | ? | 2 | ? | ? |
| Remarks | ||||
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear face shield or eye protection in combination with breathing protection.
Protective gloves. Protective clothing.
Use ventilation, local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Liquid.
-
Colour：
Colourless to pale yellow.
-
Odour：
no data available
-
Melting point/freezing point：
-15.2 °C.
-
Boiling point or initial boiling point and boiling range：
71.78 °C. Atm. press.:1 013 hPa. Remarks:Extrapolated value.
-
Flammability：
no data available
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
> 100 °C.
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
-
pH：
0.45. Remarks:Aqueous solution.
-
Kinematic viscosity：
dynamic viscosity (in mPa s) = 0.9 - 9. Temperature:20°C. Remarks:Shear rate from 20 to 100 s-1.;dynamic viscosity (in mPa s) = 1.8. Temperature:20°C. Remarks:Mean of n=10 x 3 measurements; SD=0.10; constant shear rate 2000 s-1.;dynamic viscosity (in mPa s) = 1.6. Temperature:40°C. Remarks:Mean of n=10 x 3 measurements; SD=0.01; constant shear rate 2000 s-1.
-
Solubility：
Miscible with water
-
Partition coefficient n-octanol/water：
log Pow = -2.1. Remarks:Thus, 1997.;log Pow = -0.2. Remarks:Calculated according to Rekker.;log Pow = 0.325. Remarks:ClogP for Windows V 1.0.0.
-
Vapour pressure：
12.4 kPa. Temperature:20 °C. Remarks:Value calculated from the Antoine equation.;15.8 kPa. Temperature:25 °C. Remarks:Value calculated from the Antoine equation.;139 kPa. Temperature:80 °C. Remarks:Value extrapolated from the Antoine equation.
-
Density and/or relative density：
1.479 g/cm3. Temperature:24.77 °C.;1.455 g/cm3. Temperature:34.93 °C.;1.431 g/cm3. Temperature:44.86 °C.
-
Relative vapour density：
3.9 (vs air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
no data available
Chemical stability
no data available
Possibility of hazardous reactions
The vapour is heavier than air.Decomposes on contact with hot surfaces or flames. This produces toxic fumes. The substance is a medium strong acid. Reacts violently with strong bases, reducing agents and oxidants. This produces toxic and corrosive fumes including hydrogen fluoride. Attacks many metals. This produces flammable/explosive gas (hydrogen - see ICSC 0001). Attacks some forms of rubber.
Conditions to avoid
no data available
Incompatible materials
no data available
Hazardous decomposition products
no data available
SECTION 11: Toxicological information
Acute toxicity
- Oral: no data available
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation of fumes may cause lung oedema. See Notes.
STOT-repeated exposure
no data available
Aspiration hazard
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 - Danio rerio (previous name: Brachydanio rerio) - > 1 200 mg/L - 96 h. Remarks:Na-TFA.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - > 1 200 mg/L - 48 h. Remarks:NaTFA.
- Toxicity to algae: EC50 - Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum) - 5.4 μmol/L - 72 h.
- Toxicity to microorganisms: EC50 - activated sludge, domestic - > 1 000 mg/L - 3 h. Remarks:NaTFA.
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
no data available
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN2699 (For reference only, please check.)
IMDG: UN2699 (For reference only, please check.)
IATA: UN2699 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: TRIFLUOROACETIC ACID (For reference only, please check.)
IMDG: TRIFLUOROACETIC ACID (For reference only, please check.)
IATA: TRIFLUOROACETIC ACID (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 8 (For reference only, please check.)
IMDG: 8 (For reference only, please check.)
IATA: 8 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential.