Prometryn SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Prometryn
- CAS： 7287-19-6
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Warning
H410 Very toxic to aquatic life with long lasting effects
P273 Avoid release to the environment.
P391 Collect spillage.
none
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Prometryn
- Common names and synonyms: Prometryn
- CAS number: 7287-19-6
- EC number: 230-711-3
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
Rinse with pure water for at least 15 minutes. Consult a doctor.
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Most important symptoms/effects, acute and delayed
Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: Inhalation of material may be harmful. Contact may cause burns to skin and eyes. Inhalation of Asbestos dust may have a damaging effect on the lungs. Fire may produce irritating, corrosive and/or toxic gases. Some liquids produce vapors that may cause dizziness or suffocation. Runoff from fire control may cause pollution. (ERG, 2016)
Indication of immediate medical attention and special treatment needed, if necessary
Skin decontamination. Skin contamination should be treated promptly by washing with soap and water. Contamination of the eyes should be treated immediately by prolonged flushing of the eyes with large amounts of clean water. If dermal or ocular irritation persists, medical attention should be obtained without delay. Other herbicides
SECTION 5: Firefighting measures
Suitable extinguishing media
If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped or safely confined. Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use "alcohol" foam, carbon dioxide or dry chemical. Triazine pesticides, liquid, NOS
Specific hazards arising from the chemical
Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: Some may burn but none ignite readily. Containers may explode when heated. Some may be transported hot. For UN3508, be aware of possible short circuiting as this product is transported in a charged state. (ERG, 2016)
Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.
Environmental precautions
Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up
Environmental considerations- land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner./ Dike surface flow using soil, sand bags, foamed polyurethane, or foamed concrete. Absorb bulk liquid with fly ash, cement powder, or commercial sorbents. Triazine pesticides, liquid, NOS
SECTION 7: Handling and storage
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
SECTION 8: Exposure controls/personal protection
Control parameters
no data available
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
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Physical state：
Prometryn is a colorless crystals. Used as an herbicide.
-
Colour：
Crystals
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Odour：
Odorless.
-
Melting point/freezing point：
118-120°C
-
Boiling point or initial boiling point and boiling range：
634.5°C at 760 mmHg
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Flammability：
no data available
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
2°C
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Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
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pH：
no data available
-
Kinematic viscosity：
no data available
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Solubility：
Solubilities in organic solvents at 25 deg C. Solvent g/L Acetone 330 Ethanol 140 Hexane 6.3 Toluene 200 n-Octanol 110
-
Partition coefficient n-octanol/water：
log Kow = 3.51
-
Vapour pressure：
1.24X10-6 mm Hg at 25 deg C
-
Density and/or relative density：
1.157
-
Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
No rapid reaction with air. No rapid reaction with water.
Chemical stability
Very stable over several yr of shelf life, with only slight sensitivity to natural light & extreme temp which would occur normally.
Possibility of hazardous reactions
A triazine derivative. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Conditions to avoid
no data available
Incompatible materials
no data available
Hazardous decomposition products
When heated to decomposition it emits very toxic fumes of /nitrous and sulfoxides/.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 5233 mg/kg Technical
- Inhalation: LC50 Rat inhalation 5.17 mg/L/4 hr
- Dermal: LD50 Rat percutaneous >3100 mg/kg
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Cancer Classification: Group E Evidence of Non-carcinogenicity for Humans
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 /Oncorhynchus mykiss/ (Rainbow trout) 2.5 mg/L/96 hr /Conditions of bioassay not specified in source examined
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: It has been reported that the methylthio group of prometryne is oxidized by soil microorganisms to the sulfoxide and sulfone; the sulfone is hydrolyzed to 2,4-bis(isopropylamino)-6-hydroxy-1,3,5-triazine(1). Adaptation and enrichment of viable microbial populations may be necessary for the degradation of methylthio-s-triazines such as prometryne(2). The half-life for degradation of prometryne incorporated into soil under field conditions has been observed to range from nearly 120 days to 145 days(3). Prometryne was shown to degrade, type of degradation not specified, in the field with a half-life of 58 days and in the laboratory experiments with half-lives of 64 days for surface soil (0-25 cm, pH 5.3, 0.53% organic carbon, 98% sand) and 141 days for subsurface soil (25-50 cm, pH 5.5, 0.15% organic carbon, 98% sand)(4). The time required for decomposition of prometryne in soil has been reported as 1 to 6 months; however, whether this refers to total degradation of parent as well as active metabolites is unknown(5). Residual activity of prometryne incorporated into soil at selective rates for specific soil types is from 1-3 months under most normal conditions(6). Half-life for the biodegradation of prometryne in aerobic soil has been reported as 150 days(7). Prometryne was applied at 2 kg a.i./ha along with diazinon, and measurements were made to determine the extent of dissipation in orchard soils(8). Concns dropped from 967 ng/g to 400 ng/g in the 67 day study period(8). Soils received an initial application of prometryne followed by a 4 year aging period. Several more treatments were then given to this soil over a 6 month period(9). After the initial 4 year period, 53.5% of the initial radiolabel was present as bound residues; after the 6 month period of multiple treatments, bound residues decreased to 33.2% while extractable residues increased to 50.9% of the total radiolabel(9). Prometryne has been shown to be susceptible to degradation by Nocardiodes sp.(10).
Bioaccumulative potential
An estimated BCF of 48 was calculated in fish for prometryne(SRC), using a log Kow of 3.51(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is moderate(SRC).
Mobility in soil
Koc values of 300 and 600 were measured for prometryne in soil at a pH of 7 and 5, respectively(1). Koc values of 200, 320, 808, and 1000 were measured in batch adsorption experiments at 10 deg C using river sediment from 4 different locations on the same river(2). According to a classification scheme(3), these Koc values suggest that prometryne is expected to have slight to very high mobility in soil(SRC).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN1648 (For reference only, please check.)
IMDG: UN1648 (For reference only, please check.)
IATA: UN1648 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: ACETONITRILE (For reference only, please check.)
IMDG: ACETONITRILE (For reference only, please check.)
IATA: ACETONITRILE (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 3 (For reference only, please check.)
IMDG: 3 (For reference only, please check.)
IATA: 3 (For reference only, please check.)
Packing group, if applicable
ADR/RID: II (For reference only, please check.)
IMDG: II (For reference only, please check.)
IATA: II (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/