Phosphine SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Phosphine
- CAS： 7803-51-2
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Gases under pressure: Compressed gas
Flammable gases, Category 1A, Flammable gas
Skin corrosion, Sub-category 1B
Acute toxicity - Category 2, Inhalation
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
GHS label elements, including precautionary statements
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Pictogram(s)
- Signal word Danger
H220 Extremely flammable gas
H314 Causes severe skin burns and eye damage
H330 Fatal if inhaled
H400 Very toxic to aquatic life
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P271 Use only outdoors or in a well-ventilated area.
P284 [In case of inadequate ventilation] wear respiratory protection.
P273 Avoid release to the environment.
P377 Leaking gas fire: Do not extinguish, unless leak can be stopped safely.
P381 In case of leakage, eliminate all ignition sources.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P363 Wash contaminated clothing before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316 Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P320 Specific treatment is urgent (see ... on this label).
P391 Collect spillage.
P410+P403 Protect from sunlight. Store in a well-ventilated place.
P403 Store in a well-ventilated place.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Phosphine
- Common names and synonyms: Phosphine
- CAS number: 7803-51-2
- EC number: 232-260-8
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Half-upright position. Administration of oxygen may be needed. Artificial respiration may be needed. Refer immediately for medical attention.
ON FROSTBITE: rinse with plenty of water, do NOT remove clothes. Refer for medical attention .
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Most important symptoms/effects, acute and delayed
Phosphine is a super- toxic gas with a probable oral lethal dose of 5 mg/kg or 7 drops for a 150 pound person. An air concentration of 3 ppm is safe for long term exposure, 500 ppm is lethal in 30 minutes, and a concentration of 1,000 ppm is lethal after a few breaths. (EPA, 1998)
Indication of immediate medical attention and special treatment needed, if necessary
Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary . Monitor for shock and treat if necessary . Anticipate seizures and treat if necessary . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport . Phosphine and Related Compounds
SECTION 5: Firefighting measures
Suitable extinguishing media
Evacuation: If fire becomes uncontrollable or container is exposed to direct flame - consider evacuation of one-third (1/3) mile radius.
Specific hazards arising from the chemical
Phosphine can explode with powerful oxidizers. The gas is heavier than air and may travel along the ground to an ignition source. Container may explode in heat of fire. When heated to decomposition, it emits highly toxic fumes of phosphorus oxides. Reacts violently with: air; boron trichloride; bromine; chlorine; chlorine monoxide; nitric acid; nitric oxide; nitrous oxide; nitrogen trioxide; silver nitrate; nitrous acid; mercuric nitrate; nitrogen trichloride; oxygen; and (potassium plus ammonia). Stable up to 131F. May become unstable at high temperatures. (EPA, 1998)
Special protective actions for fire-fighters
Shut off supply; if not possible and no risk to surroundings, let the fire burn itself out. In other cases extinguish with powder, carbon dioxide. In case of fire: keep cylinder cool by spraying with water. Combat fire from a sheltered position.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Evacuate danger area! Consult an expert! Ventilation. Personal protection: chemical protection suit including self-contained breathing apparatus.
Environmental precautions
Evacuate danger area! Consult an expert! Ventilation. Personal protection: chemical protection suit including self-contained breathing apparatus.
Methods and materials for containment and cleaning up
Arsine and phosphine were removed from waste gases of semiconductor manufacture by ozone oxidation and carbon adsorption.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames, NO sparks and NO smoking. NO contact with hot surfaces. Closed system, ventilation, explosion-proof electrical equipment and lighting. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Fireproof. Keep in a well-ventilated room.STORAGE INSTRUCTIONS. INDOOR STORAGE The storage of poison gases in occupied spaces is not recommended. Indoor storage in a separate building with no other occupancy is suitable. The building should be adequately ventilated and equipped with a continuous phosphine monitoring and alarm system that is activated at the TLV of 0.3 ppm. In some jurisdictions, the indoor storage of toxic gases is prohibited. OUTDOOR STORAGE. It is recommended that both full and used VAPORPH3OS Phosphine Fumigant cylinders be stored outdoors in a dedicated and properly designed and labeled storage area. The following are recommended for outdoor storage: A firm and level surface, preferably reinforced concrete, well drained. A secured and locked area. Cylinders should never be stored where the temperature will exceed 125 deg F (51.7 deg C). A means of securing all cylinders. Away from building ventilation intakes. SECURING CYLINDERS. Cylinders must be stored in an upright position and protected from falling. Protection against falls can include the use of cylinder pallets with straps, walls and securing chains, or pens constructed from steel handrail or like construction. VAPORPH3OS Phosphine Fumigant
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 0.1 ppm as TWA; (ceiling value): 0.15 ppm as STEL; A4 (not classifiable as a human carcinogen).MAK: 0.14 mg/m3, 0.1 ppm; peak limitation category: II(2); pregnancy risk group: C.EU-OEL: 0.14 mg/m3, 0.1 ppm as TWA; 0.28 mg/m3, 0.2 ppm as STEL
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear face shield or eye protection in combination with breathing protection.
Cold-insulating gloves. Protective clothing.
Use closed system or ventilation.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
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Physical state：
Phosphine is a colorless gas with a disagreeable odor of fish or garlic. Boiling point -126°F; freezing point -209°F. Very toxic by inhalation at extremely low concentrations. Prolonged heating may cause containers to rupture violently and rocket. Rate of onset: Immediate & Delayed (Lungs) Persistence: Minutes - hours Odor threshold: 0.9 ppm Source/use/other hazard: Insecticide; used in manufacture of flame retardants and incendiaries.
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Colour：
Colorless gas [Note: Shipped as a liquefied compressed gas].
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Odour：
Disagreeable, garlic-like odor.
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Melting point/freezing point：
-133.78°C
-
Boiling point or initial boiling point and boiling range：
?87.5°C(lit.)
-
Flammability：
Extremely flammable. May ignite spontaneously on contact with air. Gives off irritating or toxic fumes (or gases) in a fire.
-
Lower and upper explosion limit/flammability limit：
Lower flammable limit: 1.6% by volume; Upper flammable limit: 98 (est) % by volume
-
Flash point：
Flammable gas
-
Auto-ignition temperature：
212 deg F (100 deg C)
-
Decomposition temperature：
no data available
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pH：
SOLN ARE NEUTRAL
-
Kinematic viscosity：
1.69 cP at 50 deg C (liquid)
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Solubility：
Slight (NIOSH, 2016)
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Partition coefficient n-octanol/water：
no data available
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Vapour pressure：
760 mm Hg at -125.5° F (EPA, 1998)
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Density and/or relative density：
1.15 (vs air)
-
Relative vapour density：
1.15 (vs air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes on heating and on burning. This produces toxic fumes including phosphorus oxides. Reacts violently with air, oxygen, oxidants such as chlorine oxides, nitrogen oxides, metal nitrates, halogens and many other substances. This generates fire and explosion hazard. Attacks many metals.
Phosphine decomposes on heating or on burning, producing toxic fumes.Phosphine reacts with acids, air, copper, moisture, and oxidants.
Chemical stability
Stable up to 55 deg c
Possibility of hazardous reactions
Pure phosphine does not spontaneously ignite in air below 150 deg C unless it is thoroughly dried, when it ignites in cold air. The presence of traces (0.2%) of diphosphane in phosphine as normally prepared causes it to ignite spontaneously in air, even at below -15 deg C ... Traces of oxidants promote pyrophoricity.The gas is heavier than air and may travel along the ground; distant ignition possible.,Vapors are heavier than air. They will spread along the ground and collect and stay in poorly-ventilated, low-lying, or confined areas (e.g., sewers, basements, and tanks).Hazardous concentrations may develop quickly in enclosed, poorly-ventilated, or low-lying areas. Keep out of these areas. Stay upwind.PHOSPHINE is a reducing agent. Ignites spontaneously in air when pure [Sidgwick, 1950, p. 729]. Liquefied phosphine can be detonated [Rust, 1948, p. 301]. Ignites or reacts violently with boron trichloride, dichlorine oxide, halogens (bromine, chlorine, iodine), metal nitrates, nitrogen oxides, nitric acid, nitrous acid, nitrogen trichloride [Bretherick, 5th ed., 1995, p. 1562]. Forms explosive mixtures with even small amounts of oxygen. Autoignites at low pressures [Fisher, E. O. et al., Angew. Chem., 1968, 7, p. 136].
Conditions to avoid
no data available
Incompatible materials
Combines violently with oxygen & halogens.
Hazardous decomposition products
When heated to decomp ... emits toxic fumes of /phosphorus oxides/.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat (Charles-River, female) oral 3.03 mg/kg
- Inhalation: LC50 Rat (male) inhalation 11 ppm/4 hr
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Cancer Classification: Group D Not Classifiable as to Human Carcinogenicity
Reproductive toxicity
No information is available on the reproductive or developmental effects of phosphine in humans. No reproductive or developmental effects were observed in female rats or male mice exposed to phosphine via inhalation. No impairment in reproductive function was observed in a study of rats exposed to phosphine in their diet.
STOT-single exposure
The substance is severely irritating to the respiratory tract. Inhalation of this gas may cause lung oedema. See Notes. Rapid evaporation of the liquid may cause frostbite. The substance may cause effects on the central nervous system, cardiovascular system, heart, gastrointestinal tract, liver and kidneys. This may result in impaired functions. Exposure above the OEL could cause unconsciousness and death. Medical observation is indicated.
STOT-repeated exposure
Non-specific complaints like gastrointestinal disorders, headache, nausea etc. may occur.
Aspiration hazard
A harmful concentration of this gas in the air will be reached very quickly on loss of containment.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: no data available
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
Phosphine is a gas(1) and expected to volatilize rapidly from water and both moist and dry soil(SRC) however studies have shown that phosphine may bind to soil(2). Laboratory studies do suggest that phospine present below the soil surface is quicikly adsorbed and degraded(3). A 50% degradation rate after 11 days in water saturated soil was observed using gaseous phosphine added to soil headspace at 1000 mg/kg dry soil in closed containers(3). Phosphine interaction with soil is soil-type dependent(3).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN3525 (For reference only, please check.)
IMDG: UN3525 (For reference only, please check.)
IATA: UN3525 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: PHOSPHINE, ADSORBED (For reference only, please check.)
IMDG: PHOSPHINE, ADSORBED (For reference only, please check.)
IATA: PHOSPHINE, ADSORBED (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 2.3 (For reference only, please check.)
IMDG: 2.3 (For reference only, please check.)
IATA: 2.3 (For reference only, please check.)
Packing group, if applicable
ADR/RID: (For reference only, please check.)
IMDG: (For reference only, please check.)
IATA: (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Turn leaking cylinder with the leak up to prevent escape of gas in liquid state.The technical product often ignites spontaneously at room temperature because of the presence of other phosphorus hydrides, especially diphosphine (CAS:13445-5-6) as impurities.Odourless when pure at concentrations up to 200 ppm (278 mg/m3) (a highly toxic level).Technical product has odour of garlic or decaying fish due to impurities.The odour warning when the exposure limit value is exceeded is insufficient.The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential.Immediate administration of an appropriate inhalation therapy by a doctor, or by an authorized person, should be considered.