Glycerol trinitrate SDS

Explosives, Division 1.1

Acute toxicity - Category 2, Oral

Acute toxicity - Category 1, Dermal

Acute toxicity - Category 2, Inhalation

Specific target organ toxicity – repeated exposure, Category 2

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

H201 Explosive; mass explosion hazard

H300 Fatal if swallowed

H310 Fatal in contact with skin

H330 Fatal if inhaled

H373 May cause damage to organs through prolonged or repeated exposure

H411 Toxic to aquatic life with long lasting effects

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.

P230 Keep wetted with ...

P234 Keep only in original packaging.

P240 Ground and bond container and receiving equipment.

P250 Do not subject to grinding/shock/friction/….

P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

P264 Wash ... thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P262 Do not get in eyes, on skin, or on clothing.

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P271 Use only outdoors or in a well-ventilated area.

P284 [In case of inadequate ventilation] wear respiratory protection.

P273 Avoid release to the environment.

P370+P372+P380+P373 In case of fire: Explosion risk. Evacuate area. DO NOT fight fire when fire reaches explosives.

P301+P316 IF SWALLOWED: Get emergency medical help immediately.

P321 Specific treatment (see ... on this label).

P330 Rinse mouth.

P302+P352 IF ON SKIN: Wash with plenty of water/...

P316 Get emergency medical help immediately.

P361+P364 Take off immediately all contaminated clothing and wash it before reuse.

P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P320 Specific treatment is urgent (see ... on this label).

P319 Get medical help if you feel unwell.

P391 Collect spillage.

P401 Store in accordance with…

P405 Store locked up.

P403+P233 Store in a well-ventilated place. Keep container tightly closed.

P503 Refer to manufacturer/supplier… for information on disposal/recovery/recycling.

P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

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Fresh air, rest. Refer for medical attention.

Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer immediately for medical attention.

Exposure Routes: inhalation, skin absorption, ingestion, skin and/or eye contact Symptoms: Throbbing headache; dizziness; nausea, vomiting, abdominal pain; hypotension; flush; palpitations; methemoglobinemia; delirium, central nervous system depression; angina; skin irritation Target Organs: cardiovascular system, blood, skin, central nervous system (NIOSH, 2016)

Exposure Routes: inhalation, skin absorption, ingestion, skin and/or eye contact Symptoms: Throbbing headache; dizziness; nausea, vomiting, abdominal pain; hypotension; flush; palpitations; methemoglobinemia; delirium, central nervous system depression; angina; skin irritation Target Organs: cardiovascular system, blood, skin, central nervous system (NIOSH, 2016)

Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]: Inhalation or contact with material may irritate or burn skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control may cause pollution. (ERG, 2016)

Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]: Inhalation or contact with material may irritate or burn skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control may cause pollution. (ERG, 2016)

Excerpt from ERG Guide 112 [Explosives* - Division 1.1, 1.2, 1.3 or 1.5]: Fire may produce irritating, corrosive and/or toxic gases. (ERG, 2016)

Maintain an open airway and assist ventilation if necessary. Administer supplemental oxygen. Treat hypotension with supine positioning, intravenous crystalloid fluids, and low-dose pressors if needed. Administer activated charcoal.

If material on fire or involved in fire: Dangerously explosive. Do not fight fires in a cargo of explosives. Evacuate area and let burn. If the material is on fire or involved in fire consider evacuation of one mile radius.

Excerpt from ERG Guide 113 [Flammable Solids - Toxic (Wet/Desensitized Explosive)]: Flammable/combustible material. May be ignited by heat, sparks or flames. DRIED OUT material may explode if exposed to heat, flame, friction or shock; treat as an explosive, refer to ERG Guide 112. Keep material wet with water or treat as an explosive, refer to ERG Guide 112. Runoff to sewer may create fire or explosion hazard. (ERG, 2016)

Excerpt from ERG Guide 112 [Explosives* - Division 1.1, 1.2, 1.3 or 1.5]: MAY EXPLODE AND THROW FRAGMENTS 1600 METERS (1 MILE) OR MORE IF FIRE REACHES CARGO. For information on "Compatibility Group" letters, refer to Glossary section. (ERG, 2016)

Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water. (ERG, 2016)

Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water. (ERG, 2016)

Excerpt from ERG Guide 112 [Explosives* - Division 1.1, 1.2, 1.3 or 1.5]: MAY EXPLODE AND THROW FRAGMENTS 1600 METERS (1 MILE) OR MORE IF FIRE REACHES CARGO. For information on "Compatibility Group" letters, refer to Glossary section. (ERG, 2016)

Use water spray, powder, foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water. Combat fire from a sheltered position.

Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Remove all ignition sources. Do NOT wash away into sewer. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Remove all ignition sources. Do NOT wash away into sewer. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

Nitro-compounds and nitrate ester are cathodically reduced from industrial wastewaters.

NO open flames, NO sparks and NO smoking. NO contact with hot surfaces. Closed system, ventilation, explosion-proof electrical equipment and lighting. Use non-sparking handtools. Do NOT expose to friction or shock. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Store only if stabilized. Store in an area without drain or sewer access. Fireproof. Well closed. Separated from food and feedstuffs.Nitroglycerin injections are practically colorless and stable in their intact containers. The solutions are not explosive. Storage should be at room temperature; the containers should be protected from freezing. Exposure to light, even high intensity light, does not adversely affect nitroglycerin stability. nitroglycerin injections

TLV: 0.05 ppm as TWA; (skin).MAK: 0.094 mg/m3, 0.01 ppm; peak limitation category: II(1); skin absorption (H); carcinogen category: 3B; pregnancy risk group: C.EU-OEL: 0.095 mg/m3, 0.01 ppm as TWA; 0.19 mg/m3, 0.02 ppm as STEL; (skin)

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Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

Wear face shield or eye protection in combination with breathing protection.

Protective gloves. Protective clothing.

Use ventilation, local exhaust or breathing protection.

no data available

Heating may cause violent combustion or explosion. May decompose explosively on shock, friction or concussion. On combustion, forms toxic fumes including nitrogen oxides. Reacts with ozone. This generates explosion hazard.

Tablets of nitorglycerin are stable but should be dispensed in glass containers and protected from moisture, light and extremes of temperature.

GLYCERYL TRINITRATE SOLUTION is incompatible with the following: Heat, ozone, shock, acids. Note: An OSHA Class A Explosive (1910.109). (NIOSH, 2016). It may react vigorously with reducing agents, including hydrides, sulfides and nitrides. Incompatible with ozone, acids.

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Heat, ozone, shock acids.

Begins to decompose at 50-60 deg C, appreciable volatile at 100 deg C evolves nitrous yellow vapors at 135 deg C.

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The substance is irritating to the eyes. The substance may cause effects on the cardiovascular system. This may result in lowering of blood pressure. Medical observation is indicated.

Repeated or prolonged contact with skin may cause dermatitis. Repeated exposure leads to marked tolerance and short absence from exposure may lead to sudden death.

A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster.

Nitroglycerin and other aliphatic nitric acid esters undergo aerobic biodegradation readily via successive removal of nitrate groups to isomeric derivatives(1). Contrary to some earlier reports that it was recalcitrant to biodegradation, nitroglycerin proved to be readily biodegradable in batch and continuous tests(2). Results of the shake flask test that was run at 30 deg C with an activated sludge inoculum showed a 53.6% loss of nitroglycerin in 5 days(2). In a continuous bench-scale activated sludge apparatus, a mean reduction of 92.2% was obtained(2). The apparatus was run at room temperature and the residence time was 84 hr. 1,3-Dinitroglycerol and 1,2-dinitroglycerol were identified at intermediate stages of the process, but they were also essentially absent from the effluent(2). The third experiment employing a chemostat, a continuous culture, aerobic system with no solids recycling, was designed to simulate a plant where propellant wastes would be treated. After a 8-15 hr detention period, no nitrate esters were detectable in the effluent(2). It was found that nitroglycerin is not suitable as a source of carbon and nitrogen so nutrients are essential(2). It was speculated that the earlier experiments which showed nitroglycerin to be recalcitrant were conducted using concns of nitroglycerin that were toxic to the microorganisms(2).

An estimated BCF of 4 was calculated for nitroglycerin(SRC), using a log Kow of 1.62(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

The Koc of nitroglycerin is estimated as 180(SRC), using a log Kow of 1.62(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that nitroglycerin is expected to have moderate mobility in soil(SRC).

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The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

ADR/RID: UN0143 (For reference only, please check.)

IMDG: UN0143 (For reference only, please check.)

IATA: UN0143 (For reference only, please check.)

ADR/RID: NITROGLYCERIN, DESENSITIZED with not less than 40% non-volatile water-insoluble phlegmatizer, by mass? (For reference only, please check.)

IMDG: NITROGLYCERIN, DESENSITIZED with not less than 40% non-volatile water-insoluble phlegmatizer, by mass? (For reference only, please check.)

IATA: NITROGLYCERIN, DESENSITIZED with not less than 40% non-volatile water-insoluble phlegmatizer, by mass? (For reference only, please check.)

ADR/RID: 1.1D (For reference only, please check.)

IMDG: 1.1D (For reference only, please check.)

IATA: 1.1D (For reference only, please check.)

ADR/RID: (For reference only, please check.)

IMDG: (For reference only, please check.)

IATA: (For reference only, please check.)

ADR/RID: Yes

IMDG: Yes

IATA: Yes

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Combustion in a confined space may turn into detonation.Use of alcoholic beverages enhances the harmful effect.Other UN numbers are: UN 0144 Nitroglycerin, solution in alcohol with more than 1% but not more than 10% nitroglycerin; UN Haz Class 1.1D.UN 1204 Nitroglycerin, solution in alcohol with not more than 1% of nitroglycerin; UN Haz Class 3, Pack Group II.UN 3064 Nitroglycerin, solution in alcohol with more than 1% but not more than 5% of nitroglycerin, UN Haz Class 3, Pack Group II.An added stabilizer or inhibitor can influence the toxicological properties of this substance; consult an expert.