Methylhydrazine SDS

Carcinogenicity, Category 1B

H350 May cause cancer

P203 Obtain, read and follow all safety instructions before use.

P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

P318 IF exposed or concerned, get medical advice.

P405 Store locked up.

P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

no data available

Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.

First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. Refer for medical attention .

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention .

Methyl hydrazine vapors are extremely toxic and the liquid is corrosive to skin. Methyl hydrazine is the strongest convulsant and the most toxic of methyl-substituted hydrazine derivatives. It is more toxic than hydrazine. At high doses, it is a strong central nervous system poison that can lead to convulsions and death. Skin rash may be aggravated by skin exposure. (EPA, 1998)

Specific treatment for exposure consists of thorough washing of all exposed skin areas with soap and water, copious irrigation of the eyes, and prompt removal of the patient from the source of exposure. Hydrazines

Use flooding quantities of water. Use water spray to keep fire-exposed containers cool. Fight fire from protected location or maximum possible distance. Approach fire from upwind to avoid hazardous vapors and toxic decomposition products.

Extremely flammable; ignites spontaneously under almost all normal temperature conditions. Water used to extinguish a fire may cause pollution and should be diked for later disposal. Water may be ineffective in extinguishing fires due to the chemical's low flash point. Because of the wide flammability limits, low flash point, and reignition hazard, dry chemicals, carbon dioxide, water spray, and foam may not be as effective as water dilution of fire area. The vapor is heavier than air; thus it may accumulate sufficiently to flash back. Methylhydrazine fires produce irritating nitrogen oxides. Ignites spontaneously in air when in contact with porous materials (e.g., earth, asbestos, wood, or cloth). Also ignites spontaneously on contact with strong oxidizing agents (e.g., fluorine, chlorine trifluoride, fuming nitric acid, and nitrogen tetroxide). Heat or flame should be avoided because chemical is extremely flammable and explosive. (EPA, 1998)

Use water in large amounts, powder, alcohol-resistant foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water. Combat fire from a sheltered position.

Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment.

Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment.

Wear butyl rubber gloves, self-contained breathing apparatus, eye protection and impervious clothing. Body shield should be available. Eliminate all sources of ignition and flammables. On skin or clothing. Wash skin immediately. Remove contaminated clothing at once. Spills: Cover spill with a 1:1:1 mixture by weight of sodium carbonate or calcium carbonate, clay cat litter (bentonite) and sand. Scoop the solid into a container, transport to the fume hood and slowly add to water allowing 20 ml water for each 1 g of methylhydrazine. Filter off the clay and sand. For each 1 g of methylhydrazine, place 41 ml (about 25% excess) of commercial laundry bleach (containing about 5.25% sodium hypochlorite) into a 3-necked round-bottom flask equipped with a stirrer, thermometer and dropping funnel. Add the aqueous methylhydrazine dropwise to the stirred hypochlorite solution, monitoring the rate of addition by rise in temperature. The temperature is maintained at 45-50 deg C and addition takes about 1 hour. Stirring is continued for 2 hours until the temperature gradually falls to room temperature.

NO open flames, NO sparks and NO smoking. NO contact with strong oxidizing agents. NO contact with hot surfaces. Closed system, ventilation, explosion-proof electrical equipment and lighting. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Fireproof. Separated from strong oxidants, strong acids, metal oxides, porous materials and food and feedstuffs. Dry. Well closed. Keep under inert gas.Store in a cool, dry, well-ventilated location. Separate from acids, oxidizing materials, halogens, & air. Outside or detached storage is preferred.

TLV: 0.01 ppm as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans).MAK skin absorption (H); MAK sensitization of skin (SH)

no data available

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

Wear face shield or eye protection in combination with breathing protection.

Protective gloves. Protective clothing.

Use ventilation, local exhaust or breathing protection.

no data available

20 ppm; NIOSH considers methyl hydrazine to be a potential occupational carcinogen.

May explode on heating or on contact with metal oxides. The substance may ignite spontaneously on contact with air and porous materials such as earth, asbestos, wood and cloth. Decomposes on burning. This produces toxic and corrosive gases including nitrogen oxides. The substance is a strong reducing agent. It reacts violently with oxidants. This generates fire hazard. The substance is a medium strong base. Reacts violently with strong acids.

no data available

Very dangerous fire hazard when exposed to heat or flame.The vapour mixes well with air, explosive mixtures are easily formed.METHYLHYDRAZINE is a powerful reducing agent. Ignites upon contact with oxidizing agents i.e. dinitrogen tetraoxide, hydrogen peroxide [Hawley]. Water used to extinguish a fire may cause pollution and should be diked for later disposal. Gives basic solutions with water that generate heat when water is added.

no data available

Reacts violently with oxidizing materials, oxygen, & peroxides; sometimes resulting in autoignition.

When heated to decomposition it emits toxic fumes of /nitrogen oxide/.

no data available

no data available

no data available

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A3; Confirmed animal carcinogen with unknown relevance to humans.

No information is available on the reproductive or developmental effects of methylhydrazine in humans. Malformations have not been observed in the offspring of rats orally exposed to methylhydrazine, while malformations were reported in the toad. The morphology of sperm has been reported to be affected in mice orally exposed to methylhydrazine.

The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. The substance may cause effects on the central nervous system, liver and blood. This may result in liver impairment and the formation of methaemoglobin. Exposure far above the OEL could cause death. The effects may be delayed. Medical observation is indicated.

The substance may have effects on the liver and blood. This may result in liver impairment and the formation of methaemoglobin. This substance is possibly carcinogenic to humans.

A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C.

The toxicity of methylhydrazine to microbial species was found to be sufficiently high to prevent its degradation by biological waste treatment(1). Large amounts of methylhydrazine, such as might be released from a spill, are not expected to biodegrade. However, biodegradation of lower methylhydrazine concn may occur(SRC). Methylhydrazine at 500 mg/l, present in a wastewater mixture of hydrazine compounds, was incubated with an inoculum prepared from a trickling filter plant; following a 24 hour lag period, this mixture of compounds was biodegraded as measured by oxygen uptake(2). Contaminated wastewater from the NASA Kennedy Space station was studied in batch cultures and trickle bed reactors to monitor the degradation rates of hydrazine containing rocket fuels(3,4). The half-life of methylhydrazine in batch cultures (Rhodococcus B30 or Achromobacter sp.) and trickle bed reactors was about 2.5 and 12 days, respectively(3). Biodegradation may be a significant removal process at low concentrations in soils or ambient waters, but at higher concentrations hydrazines are toxic to microorganisms(4). Concentrations of hydrazine and 1,1-dimethylhydrazine that reduced bacterial metabolism by 50% ranged from 14.6 to 145 mg/L and from 19.2 to 9,060 mg/L, respectively(5).

An estimated BCF value of 3 was calculated for methylhydrazine(SRC), using a measured log Kow of -1.05(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF value suggests that bioconcentration in aquatic organisms is low(SRC).

Using a structure estimation method based on molecular connectivity indices(1), the Koc for methylhydrazine can be estimated to be 18(SRC). According to a classification scheme(2), this estimated Koc value suggests that methylhydrazine is expected to have very high mobility in soil. The pKa of methylhydrazine is 7.87(3). This pKa value indicates that this compound will partially exist as a cation in moist soils and cations generally adsorb more strongly to organic carbon and clay than the corresponding free base(4).

no data available

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

ADR/RID: UN1244 (For reference only, please check.)

IMDG: UN1244 (For reference only, please check.)

IATA: UN1244 (For reference only, please check.)

ADR/RID: METHYLHYDRAZINE (For reference only, please check.)

IMDG: METHYLHYDRAZINE (For reference only, please check.)

IATA: METHYLHYDRAZINE (For reference only, please check.)

ADR/RID: 6.1 (For reference only, please check.)

IMDG: 6.1 (For reference only, please check.)

IATA: 6.1 (For reference only, please check.)

ADR/RID: I (For reference only, please check.)

IMDG: I (For reference only, please check.)

IATA: I (For reference only, please check.)

ADR/RID: No

IMDG: No

IATA: No

no data available

no data available

Depending on the degree of exposure, periodic medical examination is suggested.Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.Do NOT take working clothes home.Rinse contaminated clothing with plenty of water because of fire hazard.