Acute toxicity - Category 4, Oral
Acute toxicity - Category 4, Dermal
Eye irritation, Category 2
Specific target organ toxicity – single exposure, Category 3
Carcinogenicity, Category 2
H302 Harmful if swallowed
H312 Harmful in contact with skin
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H351 Suspected of causing cancer
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P203 Obtain, read and follow all safety instructions before use.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P317 Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
P318 IF exposed or concerned, get medical advice.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
no data available
Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Give a slurry of activated charcoal in water to drink. Do NOT induce vomiting.
LIQUID: Irritating to skin and eyes. Harmful if swallowed. (USCG, 1999)
Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary . For contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal . Ketones and related compounds
Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use "alcohol" foam, dry chemical or carbon dioxide.
Combustible. (USCG, 1999)
Use water spray, powder, foam, carbon dioxide.
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
If leak or spill has not ignited, use water spray to disperse vapors & to protect men attempting to stop leak.
NO open flames. Above 84°C use a closed system and ventilation. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Separated from strong oxidants, strong bases and amines.store in a cool, dry, well-ventilated location. Outside or detached storage is preferred. Separate from oxidizing materials.
TLV: 5 ppm as STEL; A3 (confirmed animal carcinogen with unknown relevance to humans).MAK: 11 mg/m3, 2 ppm; peak limitation category: I(2); carcinogen category: 3B; pregnancy risk group: C
no data available
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Wear safety spectacles.
Protective gloves.
Use ventilation, local exhaust or breathing protection.
no data available
Liquid.
None.
Peppermint-like odor
-8.1 °C.
215.3 °C. Atm. press.:1 013 hPa.
Class IIIA Combustible Liquid: Fl.P. at or above 140°F and below 200°F.
Lower 0.8% by vol; upper 3.8%
85 °C. Atm. press.:Ca. 1 013 hPa.
470 °C. Atm. press.:Ca. 1 013 hPa.
no data available
no data available
kinematic viscosity (in mm2/s) = 2.83. Temperature:20°C.
0.1 to 1 mg/mL at 64° F (NTP, 1992)
log Pow = 1.67. Temperature:20 °C. Remarks:PH not reported (not relevant for non-dissociating substance).
0.4 hPa. Temperature:20 °C. Remarks:For values at other temperatures see below.
921.5 kg/m3. Temperature:20 °C.
4.77 (vs air)
no data available
Reacts with strong oxidants, strong bases and amines.
no data available
Flammable & explosive when exposed to heat or flame.Ketones, such as ISOPHORONE, are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4. Forms explosive peroxides
no data available
Incompatible with strong oxidizers
no data available
no data available
no data available
no data available
no data available
Cancer Classification: Group C Possible Human Carcinogen
No studies were located regarding developmental or reproductive effects in humans. (-) Limited evidence in animal studies suggests that isophorone may cause birth defects such as fetal malformations and growth retardation from inhalation exposure to isophorone during pregnancy.
The substance and the vapour are irritating to the eyes and respiratory tract. The substance may cause effects on the central nervous system.
no data available
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C.
AEROBIC: Isophorone, present at 100 mg/l, reached 3% of its theoretical BOD in 2 weeks using an activated sludge inoculum at 30 mg/l and the Japanese MITI test(1). Removal of isophorone from unacclimated fresh and salt water seeded with settled domestic wastewater was 42 and 9%, respectively, after 20 days(3). Removal of isophorone from wastewater treated by various different biological treatment processes: trickling filter, activated sludge, aerated lagoon, and facultative lagoon was 19, 98, 24, and 30%, respectively(4); therefore this compound is not expected to biodegrade rapidly(SRC). A 100% loss was observed when 5 and 10 mg/l isophorone underwent a 7-day static incubation in the dark at 25 deg C under aerobic conditions using settled domestic wastewater as inoculum(2). Using a multi-level respirometric test protocol employing a sludge microbiota, a half-life of 25 days for 100 mg test compound was determined(5).
A BCF of 7 was measured for isophorone in bluegill sunfish(1). The half-life of isophorone in fish tissue was found to be 1 day(1). According to a classification scheme(2), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
The Koc of isophorone is estimated as 200(SRC), using a log Kow of 1.7(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that isophorone is expected to have moderate mobility in soil.
no data available
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
ADR/RID: No
IMDG: No
IATA: No
no data available
no data available
The occupational exposure limit value should not be exceeded during any part of the working exposure.