Germ cell mutagenicity, Category 1B
Reproductive toxicity, Category 2
H340 May cause genetic defects
H361 Suspected of damaging fertility or the unborn child
P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P318 IF exposed or concerned, get medical advice.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
no data available
Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
Rinse with pure water for at least 15 minutes. Consult a doctor.
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
SYMPTOMS: Symptoms of exposure to this compound include bone marrow suppression including megaloblastic changes, pulmonary edema and neurological reactions such as headache and dizziness. Other neurological reactions include drowsiness, disorientation, hallucinations and convulsions. Impairment of renal function may occur. Other symptoms include megaloblastic anemia, leukopenia, thrombocytopenia, gastrointestinal disturbances, mild dermatological reactions, stomatitis and alopecia. Exposure may also cause maculopapular rash, facial erythema, dysuria and fever. Symptoms of exposure to this type of compound include anorexia, nausea, vomiting, allergic reactions including skin rashes, erythema and pruritus, hypotension, malaise, weakness, anaphylaxis, vesication or irritation of the skin and mucous membranes and possible thrombophlebitis (when injected). Prolonged exposure to this type of compound may cause bone marrow depression, anemia, bleeding, immunosuppression, mouth ulcers, esophagitis, abdominal pain, hemorrhage, diarrhea, intestinal ulceration and perforation, hyperuricemia, acute renal failure due to uric acid nephropathy, hyperphosphatemia, pigmentation of the skin and nails and jaundice. ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes of NOx. (NTP, 1992)
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Poisons A and B
Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Flash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)
Wear self-contained breathing apparatus for firefighting if necessary.
Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.
Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.
ACCIDENTAL RELEASE MEASURES: Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust; Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains; Methods and materials for containment and cleaning up: Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature 2 - 8 deg C. Moisture sensitive. Keep in a dry place.
no data available
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Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
no data available
PHYSICAL DESCRIPTION: Odorless or almost odorless white to off-white crystalline solid. Tasteless. (NTP, 1992)
Needles from alcohol
no data available
206°C(lit.)
59°C/1mmHg(lit.)
no data available
no data available
102°C(lit.)
no data available
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greater than or equal to 100 mg/mL at 70° F (NTP, 1992)
no data available
2.43X10-3 mm Hg at 25 deg C (est)
1.457g/cm3
no data available
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Stable under recommended storage conditions.
An amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
no data available
Incompatible materials: Strong oxidizing agents
Special hazards arising from the substance or mixture: Carbon oxides, Nitrogen oxides (NOx)
no data available
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Evaluation: There is inadequate evidence in humans for the carcinogenicity of hydroxyurea. There is inadequate evidence in experimental animals for the carcinogenicity of hydroxyurea. Overall evaluation: Hydroxyurea is not classifiable as to its carcinogenicity to humans (Group 3).
no data available
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The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
ADR/RID: No
IMDG: No
IATA: No
no data available
no data available