Acute toxicity - Category 4, Oral
Acute toxicity - Category 4, Dermal
Skin corrosion, Sub-category 1B
Specific target organ toxicity – single exposure, Category 3
H302 Harmful if swallowed
H312 Harmful in contact with skin
H314 Causes severe skin burns and eye damage
H335 May cause respiratory irritation
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P317 Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P363 Wash contaminated clothing before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316 Get emergency medical help immediately.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P319 Get medical help if you feel unwell.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
no data available
Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.
Rinse skin with plenty of water or shower. Refer for medical attention .
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rest. Refer for medical attention . See Notes.
Vapors cause irritation of eyes and respiratory tract. Liquid irritates eyes and skin, may cause dermatitis. (USCG, 1999)
Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]: TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. (ERG, 2016)
For immediate first aid: Ensure that adequate decontamination has been carried out. If victim is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep victim quiet and maintain normal body temperature. Obtain medical attention. Organic bases\amines and related compounds
Extinguish with water, foam, dry chemical, or carbon dioxide.
Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]: Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form. (ERG, 2016)
Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]: Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form. (ERG, 2016)
Use water in large amounts, powder, alcohol-resistant foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.
Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Carefully collect remainder. Then store and dispose of according to local regulations.
Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Carefully collect remainder. Then store and dispose of according to local regulations.
Treatment of waste water containing hexamethylenediamine from polyamide mfg in reverse osmosis apparatus with cellulose acetate membranes was studied to determine the effect of hcl addition on transport of components of the soln through a membrane & to assess the possibility of changing the ph of the concn formed in the apparatus.
NO open flames. NO contact with hot surfaces. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Separated from strong oxidants and strong acids. Well closed.
TLV: 0.5 ppm as TWA
no data available
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Wear safety spectacles, face shield or eye protection in combination with breathing protection.
Protective gloves. Protective clothing.
Use ventilation (not if powder), local exhaust or breathing protection.
no data available
Solid. Crystalline.
Colourless to white.
ODOR OF PIPERIDINE
41 °C.
201 °C. Atm. press.:1 000 mBar.
Combustible.
0.7-6.3% in air
85 °C. Atm. press.:1 024 hPa.
315 °C. Atm. press.:1 027 hPa.
no data available
no data available
dynamic viscosity (in mPa s) = 1.06. Temperature:80.0°C. Remarks:Use temperature.
Miscible with water
log Pow = 0.02. Remarks:No T given, assumed to be ambient T.;Pow = 1.047 - 1.049. Remarks:No T given, assumed to be ambient T.
10 mBar. Temperature:78.47 °C. Remarks:Use temperature.
0.978. Temperature:19.5 °C.
4 (vs air)
no data available
On combustion, forms toxic and corrosive gases. Upon heating, toxic fumes are formed. This produces toxic fumes. The solution in water is a strong base. It reacts violently with acid and is corrosive. Reacts with oxidants. Attacks many metals in the presence of water.
Vaporizes readily
COMBUSTIBLE WHEN EXPOSED TO HEAT OR FLAME...HEXAMETHYLENEDIAMINE is hygroscopic. This compound can react with strong oxidizing materials. It is incompatible with acids, acid chlorides and acid anhydrides. It is also incompatible with ketones, aldehydes, nitrates, phenols, isocyanates, monomers and chlorinated compounds. (NTP, 1992).
no data available
can react with oxidizing materials.
no data available
no data available
no data available
no data available
no data available
no data available
no data available
The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation may cause lung oedema. See Notes. The effects may be delayed. Medical observation is indicated.
Repeated or prolonged contact with skin may cause dermatitis.
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.
Biodegradation is expected to be an important environmental fate for this compound(SRC). Using a standard BOD dilution technique and an activated sludge inoculum, a theoretical BOD of 56% was observed during a 14 day incubation period(1). Using standard BOD dilution techniques and activated sludge inocula, theoretical BOD values of 41% to 56% were observed during a 14 day incubation period following a 6 day acclimation period(2). Based on 14 day BOD data, hexamethylene diamine is considered biodegradable(3). Following a 3 day acclimation period, 90% biodegradation of hexamethylene diamine in an activated sludge inoculum was observed during a 6 day incubation period, with an average COD of 26% per day(4). Degradation rates of 4% and 10% were observed for hexamethylene diamine (50 ppm) incubated in water from the Mino River, Japan and seawater off the coast of Japan over a 3 day incubation period(5). A theoretical oxygen demand between 20 and 60% was observed for hexamethylene diamine in a Warburg apparatus during a 5 day incubation period(6).
An estimated BCF value of 1 was calculated for hexamethylene diamine(SRC), using an estimated log Kow of 0.35(1,SRC) and a recommended regression-derived equation(2). According to a classification scheme(3), this BCF value suggests that bioconcentration in aquatic organisms is low(SRC).
Based on a recommended classification scheme(1), an estimated Koc value of 286(SRC), determined from a structure estimation method(2), indicates that hexamethylene diamine is expected to have moderate mobility in soil(SRC).
no data available
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
ADR/RID: UN2280 (For reference only, please check.)
IMDG: UN2280 (For reference only, please check.)
IATA: UN2280 (For reference only, please check.)
ADR/RID: HEXAMETHYLENEDIAMINE, SOLID (For reference only, please check.)
IMDG: HEXAMETHYLENEDIAMINE, SOLID (For reference only, please check.)
IATA: HEXAMETHYLENEDIAMINE, SOLID (For reference only, please check.)
ADR/RID: 8 (For reference only, please check.)
IMDG: 8 (For reference only, please check.)
IATA: 8 (For reference only, please check.)
ADR/RID: III (For reference only, please check.)
IMDG: III (For reference only, please check.)
IATA: III (For reference only, please check.)
ADR/RID: No
IMDG: No
IATA: No
no data available
no data available
The substance may exist as solid or liquid depending on ambient temperature.The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort.Rest and medical observation is therefore essential.Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered.The recommendations on this Card also apply to Hexamethylenediamine solution, 70-80 %, UN No. 1783.