Chemical Book India PDF
Chemical Safety Data Sheet MSDS / SDS

Hexachlorobenzene SDS

Revision Date:2024-04-25 Revision Number:1
Section 1 Section 2 Section 3 Section 4 Section 5 Section 6 Section 7 Section 8 Section 9 Section 10 Section 11 Section 12 Section 13 Section 14 Section 15 Section 16

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: Hexachlorobenzene
  • CAS: 118-74-1

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company:Chemicalbook.in
  • Address:5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
  • Telephone:+91 9550333722

SECTION 2: Hazards identification

Classification of the substance or mixture

Carcinogenicity, Category 1B

Specific target organ toxicity – repeated exposure, Category 1

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

GHS label elements, including precautionary statements

  • Pictogram(s)
  • Signal word Danger
Hazard statement(s)

H350 May cause cancer

H372 Causes damage to organs through prolonged or repeated exposure

H410 Very toxic to aquatic life with long lasting effects

Precautionary statement(s)
Prevention

P203 Obtain, read and follow all safety instructions before use.

P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P264 Wash ... thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P273 Avoid release to the environment.

Response

P318 IF exposed or concerned, get medical advice.

P319 Get medical help if you feel unwell.

P391 Collect spillage.

Storage

P405 Store locked up.

Disposal

P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

SECTION 3: Composition/information on ingredients

Substance

  • Chemical name: Hexachlorobenzene
  • Common names and synonyms: Hexachlorobenzene
  • CAS number: 118-74-1
  • EC number: 204-273-9
  • Concentration: 100%

SECTION 4: First aid measures

Description of necessary first-aid measures

If inhaled

Fresh air, rest. Refer for medical attention.

Following skin contact

Rinse and then wash skin with water and soap. Refer for medical attention .

Following eye contact

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Following ingestion

Rinse mouth. Refer for medical attention .

Most important symptoms/effects, acute and delayed

Harmful by dust inhalation or if swallowed. Irritating to eyes, skin and mucous membranes. Prolonged periods of ingestion may cause cutaneous porphyria. (USCG, 1999)

Indication of immediate medical attention and special treatment needed, if necessary

Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Lindane and related compounds

SECTION 5: Firefighting measures

Suitable extinguishing media

Use water spray, foam, powder, carbon dioxide.

Specific hazards arising from the chemical

Special Hazards of Combustion Products: They contain highly toxic chloride fumes. Behavior in Fire: Produces highly toxic chloride fumes. (USCG, 1999)

Special protective actions for fire-fighters

Use water spray, foam, powder, carbon dioxide.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Personal protection: chemical protection suit and particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into sealable containers. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment.

Environmental precautions

Personal protection: chemical protection suit and particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into sealable containers. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment.

Methods and materials for containment and cleaning up

Absorb the spills with paper towels or like materials. Place in hood to evaporate followed by burning the towel. Dissolve in a combustible solvent. Scatter the spray of the solution into the furnace with after burners and alkali scrubber.

SECTION 7: Handling and storage

Precautions for safe handling

NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Separated from food and feedstuffs. Well closed.Separated from food and feedstuffs. Well closed.

SECTION 8: Exposure controls/personal protection

Control parameters

Occupational Exposure limit values

TLV: 0.002 mg/m3, as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans).MAK: skin absorption (H); carcinogen category: 4; pregnancy risk group: D

Biological limit values

no data available

Appropriate engineering controls

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Wear face shield or eye protection in combination with breathing protection.

Skin protection

Protective gloves. Protective clothing.

Respiratory protection

Use local exhaust or breathing protection.

Thermal hazards

no data available

SECTION 9: Physical and chemical properties and safety characteristics

  • Physical state:

    Hexachlorobenzene is a white crystalline substance. Insoluble in water and denser than water. Contact may irritate skin, eyes and mucous membranes. May be toxic by ingestion. Used to make other chemicals.

  • Colour:

    White needles

  • Odour:

    no data available

  • Melting point/freezing point:

    228-231°C

  • Boiling point or initial boiling point and boiling range:

    332°C

  • Flammability:

    Combustible.

  • Lower and upper explosion limit/flammability limit:

    no data available

  • Flash point:

    242°C

  • Auto-ignition temperature:

    no data available

  • Decomposition temperature:

    no data available

  • pH:

    no data available

  • Kinematic viscosity:

    no data available

  • Solubility:

    less than 1 mg/mL at 68° F (NTP, 1992)

  • Partition coefficient n-octanol/water:

    log Kow = 5.73

  • Vapour pressure:

    0.000463mmHg at 25°C

  • Density and/or relative density:

    1.5691

  • Relative vapour density:

    9.8 (NTP, 1992) (Relative to Air)

  • Particle characteristics:

    no data available

SECTION 10: Stability and reactivity

Reactivity

Decomposes on heating. This produces toxic fumes.

Chemical stability

Very stable, even to acids and bases.

Possibility of hazardous reactions

Not flammable or combustible.HEXACHLOROBENZENE reacts violently with dimethylformamide. (NTP, 1992).

Conditions to avoid

no data available

Incompatible materials

Dimethyl formamide and hexachlorobenzene react violently above 65 deg c.

Hazardous decomposition products

Dangerous; When heated to decomposition, emits toxic fumes of /hydrogen chloride/.

SECTION 11: Toxicological information

Acute toxicity

  • Oral: LD50 Rat oral 3500 mg/kg
  • Inhalation: no data available
  • Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

NTP: Reasonably anticipated to be a human carcinogen

Reproductive toxicity

One human study reported abnormal physical development in young children who ingested contaminated bread during a 4-year poisoning incident. Hexachlorobenzene has been found to decrease the survival rates of newborn animals and to cross the placenta and accumulate in fetal tissue in several animal species. Neurological, teratogenic, liver, and immune system effects have been reported in the offspring of animals orally exposed to hexachlorobenzene while they were pregnant.

STOT-single exposure

no data available

STOT-repeated exposure

The substance may have effects on the liver and nervous system. This may result in impaired functions of organs and skin lesions. This substance is possibly carcinogenic to humans. Animal tests show that this substance possibly causes toxic effects upon human reproduction.

Aspiration hazard

Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying.

SECTION 12: Ecological information

Toxicity

  • Toxicity to fish: LC50; Species: Pimephales promelas (fathead minnow) weight 0.7 g; Conditions: static bioassay, 20 deg C; Concentration: 22 mg/L for 96 hr @ 20 deg C (95% confidence limit) /technical 80-96%
  • Toxicity to daphnia and other aquatic invertebrates: no data available
  • Toxicity to algae: no data available
  • Toxicity to microorganisms: no data available

Persistence and degradability

Little to no biodegradation was noted in biodegradation screening tests(1,3,4), in activated sludge(2,5), or in soil(6-8). Measurement of CO2 evolution from suspended soil cultures over a 14-day incubation period were as follows: 0.4% under aerobic conditions, 0.2% under anaerobic conditions(9).

Bioaccumulative potential

BCF values of 2,700 to 4,800 were measured in carp exposed to 10 ug/L of hexachlorobenzene during an 8 week incubation period and BCF values of 1,600 to 3,900 were measured in carp exposed to 1 ug/L of hexachlorobenzene during an 8 week incubation period(1). Log BCF values in rainbow trout (Salmo gairdneri) were given as 3.7-4.3(2-4) and in fathead minnows (Pimephales promelas) and sunfish (Lepomis cyanellus) log BCF values of 4.21 and 4.34, respectively, were reported(3). After an 8-week exposure period of carp (Cyprinus carpio) to concentrations of 0.5 and 0.05 ug/L of hexachlorobenzene, the BCFs were 11,000-27,000 and 6,000-30,000, respectively(5). According to a classification scheme(6), these BCF values suggest that bioconcentration in aquatic organisms is very high, provided the compound is not metabolized by the organism(SRC).

Mobility in soil

A log Koc value of 5.5 (Koc of 3.2X10+5) was reported for hexachlorobenzene in freshwater river sediment(1). A log Koc value of 4.9 (Koc of 7.9X10+4) was reported for hexachlorobenzene in sediment obtained from the Ise Bay, Japan(2). Measured log Koc values of 3.6 (Koc of 4X10+3)(3) and 4.0 (Koc of 1X10+4)(4) were reported in soils. Log Koc values of 6.42 and 5.56 (Koc values of 2.6X10+6 and 3.6X10+5) were determined for two sediment layers from a lake(5). Hexachlorobenzene has measured log Koc value of 3.99 (Koc of 9.8X10+3) reported for soils(6). Hexachlorobenzene was found to desorb very slowly from sediment in water(7). According to a recommended classification scheme(8), these Koc values suggest that hexachlorobenzene is expected to be immobile in soil(SRC).

Other adverse effects

no data available

SECTION 13: Disposal considerations

Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

SECTION 14: Transport information

UN Number

ADR/RID: UN2729 (For reference only, please check.)

IMDG: UN2729 (For reference only, please check.)

IATA: UN2729 (For reference only, please check.)

UN Proper Shipping Name

ADR/RID: HEXACHLOROBENZENE (For reference only, please check.)

IMDG: HEXACHLOROBENZENE (For reference only, please check.)

IATA: HEXACHLOROBENZENE (For reference only, please check.)

Transport hazard class(es)

ADR/RID: 6.1 (For reference only, please check.)

IMDG: 6.1 (For reference only, please check.)

IATA: 6.1 (For reference only, please check.)

Packing group, if applicable

ADR/RID: III (For reference only, please check.)

IMDG: III (For reference only, please check.)

IATA: III (For reference only, please check.)

Environmental hazards

ADR/RID: Yes

IMDG: Yes

IATA: Yes

Special precautions for user

no data available

Transport in bulk according to IMO instruments

no data available

SECTION 15: Regulatory information

Safety, health and environmental regulations specific for the product in question

European Inventory of Existing Commercial Chemical Substances (EINECS)
Listed.
EC Inventory
Listed.
United States Toxic Substances Control Act (TSCA) Inventory
Listed.
China Catalog of Hazardous chemicals 2015
Listed.
New Zealand Inventory of Chemicals (NZIoC)
Not Listed.
(PICCS)
Listed.
Vietnam National Chemical Inventory
Listed.
IECSC)
Listed.
Korea Existing Chemicals List (KECL)
Not Listed.

SECTION 16: Other information

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%

References

  • IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
  • HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
  • IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
  • CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
  • ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
  • Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
  • ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Other Information

Depending on the degree of exposure, periodic medical examination is suggested.Do NOT take working clothes home.

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any