Acute toxicity - Category 4, Oral
H302 Harmful if swallowed
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
none
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
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Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
Rinse with pure water for at least 15 minutes. Consult a doctor.
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
SYMPTOMS: Symptoms of exposure to this compound may include nervousness, headache, sweating, nausea and vomiting. Contact dermatitis may occur. Other symptoms include an increase in pulse rate and an increase in blood pressure. Exposure may cause irritation of the skin, eyes and respiratory tract, central nervous system effects, peripheral nervous system effects, loss of appetite, tremors and, in severe cases, convulsions, coma and death. Sleeplessness, restlessness and urinary retention may occur. This compound may cause excitation, insomnia, palpitation, tachycardia, precordial pain, cardiac arrhythmias, vertigo, dryness of the nose and throat, warmth, vesical sphincter spasm and urinary hesitation. It may also cause anxiety, extrasystoles, confusion and delirium. Other symptoms include chills, cyanosis, irritability, fever, suicidal behavior, mania, dilated pupils, blurred vision, opisthotonos, spasms, pulmonary edema, gasping respiration, respiratory failure and anuria. Exposure can lead to giddiness, thirst, difficulty in micturition, muscular weakness, hypertension and ventricular arrhythmias. Overexposure can cause paranoid psychoses, delusions and hallucinations. Mydriasis may occur. ACUTE/CHRONIC HAZARDS: This compound may cause irritation of the skin, eyes and respiratory tract. It may be harmful if swallowed. When heated to decomposition it emits toxic fumes of sulfuric acid, nitrogen oxides and sulfur oxides. (NTP, 1992)
Emergency and Supportive Measures: Maintain an open airway and assist ventilation if necessary. Administer supplemental oxygen. Treat hypertension aggressively. Treat seizures and ventricular tachyarrhythmias if they occur. Do not treat reflex bradycardia except indirectly by lowering blood pressure. Monitor the vital signs and ECG for a minimum of 4-6 hours after exposure and longer if a sustained-release preparation has been ingested. Pseudoephedrine, phenylephrine, and other decongestants
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used. (NTP, 1992)
Flash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)
Wear self-contained breathing apparatus for firefighting if necessary.
Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.
Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
must be stored in light-resistant containers. Ephedrine base should be stored at or below 8 deg C.
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Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
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PHYSICAL DESCRIPTION: White microcrystalline powder. Odorless. Central nervous system stimulant.
Waxy solid, crystals or granules
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37-39 °C(lit.)
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10.8 aqueous solution (1 in 200)
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greater than or equal to 100 mg/mL at 68° F (NTP, 1992)
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0.0012 mm Hg at 25 deg C (est)
1.0085 g/cu cm at 22 deg C
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Gradually decomp on exposure to light
Aqueous solution are slightly acidic. This chemical is incompatible with strong oxidizers. (NTP, 1992)
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When heated to decomposition it emits toxic fumes of nitrogen oxides
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AEROBIC: (L)-Ephedrine has been identified as a compound which is readily biodegradable by sewage sludge following acclimation(1,2).
An estimated BCF of 1.4 was calculated in fish for (L)-ephedrine(SRC), using a log Kow of 1.13(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Using a structure estimation method based on molecular connectivity indices(1), the Koc of (L)-ephedrine can be estimated to be 72(SRC). According to a classification scheme(2), this estimated Koc value suggests that (L)-ephedrine is expected to have high mobility in soil. The pKa of (L)-ephedrine is 9.65(3), indicating that this compound will exist predominantly in the cation form in the environment and cations generally adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(4).
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The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
ADR/RID: No
IMDG: No
IATA: No
no data available
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