Chemical Book India PDF
Chemical Safety Data Sheet MSDS / SDS

DL-methionine SDS

Revision Date:2024-04-25 Revision Number:1
Section 1 Section 2 Section 3 Section 4 Section 5 Section 6 Section 7 Section 8 Section 9 Section 10 Section 11 Section 12 Section 13 Section 14 Section 15 Section 16

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: DL-methionine
  • CAS: 59-51-8

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company:Chemicalbook.in
  • Address:5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
  • Telephone:+91 9550333722

SECTION 2: Hazards identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

  • Signal word No signal word
Hazard statement(s)

none

Precautionary statement(s)
Prevention

none

Response

none

Storage

none

Disposal

none

Other hazards which do not result in classification

no data available

SECTION 3: Composition/information on ingredients

Substance

  • Chemical name: DL-methionine
  • Common names and synonyms: DL-methionine
  • CAS number: 59-51-8
  • EC number: 200-432-1
  • Concentration: 100%

SECTION 4: First aid measures

Description of necessary first-aid measures

If inhaled

Fresh air, rest.

Following skin contact

Rinse skin with plenty of water or shower.

Following eye contact

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Following ingestion

Rinse mouth.

Most important symptoms/effects, acute and delayed

no data available

Indication of immediate medical attention and special treatment needed, if necessary

Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Poisons A and B

SECTION 5: Firefighting measures

Suitable extinguishing media

Use water spray, powder, foam, carbon dioxide.

Specific hazards arising from the chemical

Gives off irritating or toxic fumes (or gases) in a fire.

Special protective actions for fire-fighters

Use water spray, powder, foam, carbon dioxide.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Sweep spilled substance into covered containers. Carefully collect remainder. Then store and dispose of according to local regulations.

Environmental precautions

Sweep spilled substance into covered containers. Carefully collect remainder. Then store and dispose of according to local regulations.

Methods and materials for containment and cleaning up

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

SECTION 7: Handling and storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Separated from strong oxidants. Well closed.

SECTION 8: Exposure controls/personal protection

Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

Appropriate engineering controls

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Wear safety spectacles.

Skin protection

Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Use local exhaust.

Thermal hazards

no data available

SECTION 9: Physical and chemical properties and safety characteristics

  • Physical state:

    COLOURLESS CRYSTALS OR WHITE POWDER.

  • Colour:

    Minute hexagonal plates from dilute alcohol

  • Odour:

    Faint

  • Melting point/freezing point:

    112°C(lit.)

  • Boiling point or initial boiling point and boiling range:

    146°C

  • Flammability:

    Gives off irritating or toxic fumes (or gases) in a fire.

  • Lower and upper explosion limit/flammability limit:

    no data available

  • Flash point:

    43°C(lit.)

  • Auto-ignition temperature:

    no data available

  • Decomposition temperature:

    281°C

  • pH:

    pH (1% aqueous solution) = 5.6-6.1

  • Kinematic viscosity:

    no data available

  • Solubility:

    Soluble in water but the crystals are somewhat water-repellant at first

  • Partition coefficient n-octanol/water:

    log Kow = -1.87

  • Vapour pressure:

    8.14X10-8 mm Hg at 25 deg C (est)

  • Density and/or relative density:

    1.34

  • Relative vapour density:

    no data available

  • Particle characteristics:

    no data available

SECTION 10: Stability and reactivity

Reactivity

Decomposes on heating. This produces toxic fumes of sulfur oxides and nitrous oxides.

Chemical stability

no data available

Possibility of hazardous reactions

Decomposes on heating. This produces toxic fumes of sulfur oxides and nitrous oxides.

Conditions to avoid

no data available

Incompatible materials

no data available

Hazardous decomposition products

When heated to decomposition it emits very toxic fumes of /nitric oxide/ and /sulfur oxide/.

SECTION 11: Toxicological information

Acute toxicity

  • Oral: LD50 Rat oral 36,000 mg/kg
  • Inhalation: no data available
  • Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

no data available

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

SECTION 12: Ecological information

Toxicity

  • Toxicity to fish: no data available
  • Toxicity to daphnia and other aquatic invertebrates: no data available
  • Toxicity to algae: no data available
  • Toxicity to microorganisms: no data available

Persistence and degradability

AEROBIC: In a laboratory activated sludge system, (L)-methionine had an 80% theoretical BOD reduction after 16 days of incubation(1). In a Warburg respirometer study using activated sludge, (L)-methionine (at a concn of 500 mg/L) had a theoretical BOD of 2.6% over a 24-hr incubation period(2). In an activated sludge system that had been acclimated to phenol, (L)-methionine had a theoretical oxidation of 16% after 12 hrs of aeration(3).

Bioaccumulative potential

An estimated BCF of 3 was calculated in fish for (L)-methionine(SRC), using a log Kow of -1.87(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

Mobility in soil

The Koc of (L)-methionine is estimated as 8(SRC), using a log Kow of -1.87(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that (L)-methionine is expected to have very mobility in soil. The pKa values of (L)-methionine are 2.28 and 9.21(4), indicate that this compound will exist as a zwitterion which may affect its adsorption to soils and sediments(SRC). One study found that (L)-methionine was one of many amino acids that sorbed to carbonate sediments in seawater(5); a positive correlation between surface area (of the sediment) and the amount of sorbed amino acids indicated that sorption from solution (partitioning from the water column to sediment) was a likely mechanism(5).

Other adverse effects

no data available

SECTION 13: Disposal considerations

Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

SECTION 14: Transport information

UN Number

ADR/RID: Not dangerous goods. (For reference only, please check.)

IMDG: Not dangerous goods. (For reference only, please check.)

IATA: Not dangerous goods. (For reference only, please check.)

UN Proper Shipping Name

ADR/RID: Not dangerous goods. (For reference only, please check.)

IMDG: Not dangerous goods. (For reference only, please check.)

IATA: Not dangerous goods. (For reference only, please check.)

Transport hazard class(es)

ADR/RID: Not dangerous goods. (For reference only, please check.)

IMDG: Not dangerous goods. (For reference only, please check.)

IATA: Not dangerous goods. (For reference only, please check.)

Packing group, if applicable

ADR/RID: Not dangerous goods. (For reference only, please check.)

IMDG: Not dangerous goods. (For reference only, please check.)

IATA: Not dangerous goods. (For reference only, please check.)

Environmental hazards

ADR/RID: No

IMDG: No

IATA: No

Special precautions for user

no data available

Transport in bulk according to IMO instruments

no data available

SECTION 15: Regulatory information

Safety, health and environmental regulations specific for the product in question

European Inventory of Existing Commercial Chemical Substances (EINECS)
Listed.
EC Inventory
Listed.
United States Toxic Substances Control Act (TSCA) Inventory
Listed.
China Catalog of Hazardous chemicals 2015
Not Listed.
New Zealand Inventory of Chemicals (NZIoC)
Listed.
(PICCS)
Listed.
Vietnam National Chemical Inventory
Listed.
IECSC)
Listed.
Korea Existing Chemicals List (KECL)
Listed.

SECTION 16: Other information

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%

References

  • IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
  • HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
  • IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
  • CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
  • ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
  • Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
  • ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any