Dichlorobenzene SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Dichlorobenzene
- CAS： 25321-22-6
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 4, Oral
Skin irritation, Category 2
Skin sensitization, Category 1
Eye irritation, Category 2
Acute toxicity - Category 4, Inhalation
Specific target organ toxicity – single exposure, Category 3
Carcinogenicity, Category 2
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Warning
H302 Harmful if swallowed
H315 Causes skin irritation
H317 May cause an allergic skin reaction
H319 Causes serious eye irritation
H332 Harmful if inhaled
H335 May cause respiratory irritation
H351 Suspected of causing cancer
H400 Very toxic to aquatic life
H410 Very toxic to aquatic life with long lasting effects
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P271 Use only outdoors or in a well-ventilated area.
P203 Obtain, read and follow all safety instructions before use.
P273 Avoid release to the environment.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P333+P317 If skin irritation or rash occurs: Get medical help.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317 Get medical help.
P319 Get medical help if you feel unwell.
P318 IF exposed or concerned, get medical advice.
P391 Collect spillage.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Dichlorobenzene
- Common names and synonyms: Dichlorobenzene
- CAS number: 25321-22-6
- EC number: 246-837-7
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Give one or two glasses of water to drink. Do NOT induce vomiting. Refer for medical attention .
Most important symptoms/effects, acute and delayed
Chronic inhalation of mist or vapors may result in damage to lungs, liver, and kidneys. Acute vapor exposure can cause symptoms ranging from coughing to central nervous system depression and transient anesthesia. Irritating to skin, eyes, and mucous membranes. May cause dermatitis. (USCG, 1999)
Indication of immediate medical attention and special treatment needed, if necessary
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Lindane and related compounds
SECTION 5: Firefighting measures
Suitable extinguishing media
Approach fire from upwind to avoid hazardous vapors and toxic decomposition products. Use water spray, dry chemical, foam, or carbon dioxide. Use water spray to keep fire-exposed containers cool. Extinguish fire using agent suitable for surrounding fire.
Specific hazards arising from the chemical
Special Hazards of Combustion Products: Poisonous vapors including hydrogen chloride gas, chlorocarbons, chlorine (USCG, 1999)
Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.
Environmental precautions
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Land spill: Dig a pit, pond, lagoon, or holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes or holding areas should be sealed with an impermeable flexible membrane liner./ Dike surface flow using soil, sand bags, foamed polyurethane, or concrete. Absorb bulk liquid with fly ash, or cement power. Apply "universal" gelling agent to immobilize spill.
SECTION 7: Handling and storage
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Separated from aluminium, oxidants and food and feedstuffs.Store in cool, dry, well-ventilated location. Separate from oxidizing materials.
SECTION 8: Exposure controls/personal protection
Control parameters
| Component | Dichlorobenzene |
|---|---|
| CAS No. | 25321-22-6 |
|
Recommended Exposure Limit: 15-Min Ceiling Value: 50 ppm (300 mg/cu m). |
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
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Physical state：
O-dichlorobenzene is a clear colorless liquid with a pleasant odor. Denser than water and insoluble in water. Flash point 150°F. Toxic by inhalation and ingestion. Used to make other chemicals, solvents, fumigants and insecticides and for many other uses.
-
Colour：
Colorless liquid
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Odour：
Pleasant odor
-
Melting point/freezing point：
1° F (NTP, 1992)
-
Boiling point or initial boiling point and boiling range：
180.5°C at 760mmHg
-
Flammability：
Class IIIA Combustible Liquid: Fl.P. at or above 140°F and below 200°F.
-
Lower and upper explosion limit/flammability limit：
2 TO 9% BY VOL IN AIR
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Flash point：
65.6°C
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Auto-ignition temperature：
1198° F (USCG, 1999)
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Decomposition temperature：
no data available
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pH：
no data available
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Kinematic viscosity：
1.324 mPa.s at 25 deg C
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Solubility：
less than 1 mg/mL at 76.1° F (NTP, 1992)
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Partition coefficient n-octanol/water：
log Kow = 3.43
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Vapour pressure：
1 mm Hg at 68° F ; 1.5 mm Hg at 77° F (NTP, 1992)
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Density and/or relative density：
1.297g/cm3
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Relative vapour density：
5.05 (NTP, 1992) (Relative to Air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes on burning. This produces toxic and corrosive gases including hydrogen chloride. Reacts with aluminium and oxidants. Attacks plastics and rubber.
Chemical stability
no data available
Possibility of hazardous reactions
Combustible liquid.O-DICHLOROBENZENE is sensitive to prolonged exposure to light. This chemical can react vigorously with oxidizers. It is incompatible with aluminum and aluminum alloys. It attacks some forms of plastics, rubber and coatings. (NTP, 1992).
Conditions to avoid
no data available
Incompatible materials
Strong oxidizers, aluminum, chlorides, acids, acid fumes.
Hazardous decomposition products
When heated to decomposition it emits toxic /hydrogen/ chloride fumes.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Guinea pig oral 0.8-2.0 ug/kg.
- Inhalation: LC50 Mouse inhalation 6,825 mg/cu m/6 hr
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Evaluation: There is inadequate evidence in humans for the carcinogenicity of dichlorobenzenes. There is evidence suggesting a lack of carcinogenicity in experimental animals of ortho-dichlorobenzene. ... Overall evaluation: ortho-Dichlorobenzene is not classifiable as to its carcinogenicity to humans (Group 3). Dichlorobenzenes
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50; Species: Danio rerio (Zebra danio, age ~9 months, adult, weight 0.8 g, length 4.3 cm); Conditions: freshwater, static, 24 deg C, pH 7.8, hardness 350 mg/L CaCO3; Concentration: 180 mg/L for 96 hr /99% purity
- Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water flea); Conditions: renewal, 25 deg C, pH >7; Concentration: 1700 ug/L for 24 hr; Effect: behavior, equilibrium
- Toxicity to algae: EC50; Species: Pseudokirchneriella subcapitata (Green algae, initial concentration 500,000 cells/L); Conditions: static, 20 deg C; Concentration: 2200 ug/L for 96 hr; Effect: general growth
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: 1,2-Dichlorobenzene at 100 mg/L achieved 0% of its theoretical BOD using an activated sludge inoculum at 30 mg/L over a 4 week incubation period in the Japanese MITI test(1). 1,2-Dichlorobenzene was resistant to biodegradation in another Japanese MITI test study(2). Dichlorobenzene isomers were slowly biodegraded (6.3% of theoretical CO2 evolution in 10 weeks) in an alkaline soil sample(3). The rate constant for 1,2-dichlorobenzene in a heterogeneous aquifer at the Columbus Air Force Base, Mississippi was 0.0059 days-1, corresponding to a biodegradation half-life of about 117 days(4). 1,2-Dichlorobenzene is resistant to biodegradation in soils, with half-lives expected to be greater than 9 months(5).
Bioaccumulative potential
The sorption of 8 organic compounds by a representative green alga, Selenastrum capricornutum, was determined by GLC by a series of linear model experiments. The log10 bioconcentration factors (BCF), defined as the ratio of the concentration on/in the algae to the concentration in the aqueous medium, were as follows: benzene 3.32, toluene 3.18, chlorobenzene 3.69, 1,2-dichlorobenzene 4.17. The relation of log10 BCF correlation with log10 octanol-water partition coefficient (P) was determined to be log10 BCF= 0.46 log10 P + 2.36.
Mobility in soil
Experimental Koc values of 280(1) and 320(2) were determined for 1,2-dichlorobenzene in silt loam soils. A log Koc value of 3.7 was reported for 1,2-dichlorobenzene in sediment obtained from the Ise Bay, Japan(3) and a log Koc value of 4.3 was measured from sediment of Lake Ketelmeer, Netherlands(4). According to a recommended classification scheme(5), these soil Koc values suggest that 1,2-dichlorobenzene has moderate mobility in soil(SRC).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: no data available
IMDG: no data available
IATA: no data available
UN Proper Shipping Name
ADR/RID: no data available
IMDG: no data available
IATA: no data available
Transport hazard class(es)
ADR/RID: no data available
IMDG: no data available
IATA: no data available
Packing group, if applicable
ADR/RID: no data available
IMDG: no data available
IATA: no data available
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/