Chloroacetaldehyde SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Chloroacetaldehyde
- CAS： 107-20-0
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 3, Oral
Acute toxicity - Category 3, Dermal
Skin corrosion, Sub-category 1B
Acute toxicity - Category 2, Inhalation
Carcinogenicity, Category 2
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Danger
H301 Toxic if swallowed
H311 Toxic in contact with skin
H314 Causes severe skin burns and eye damage
H330 Fatal if inhaled
H351 Suspected of causing cancer
H400 Very toxic to aquatic life
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P284 [In case of inadequate ventilation] wear respiratory protection.
P203 Obtain, read and follow all safety instructions before use.
P273 Avoid release to the environment.
P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P316 Get emergency medical help immediately.
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P363 Wash contaminated clothing before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P320 Specific treatment is urgent (see ... on this label).
P318 IF exposed or concerned, get medical advice.
P391 Collect spillage.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Chloroacetaldehyde
- Common names and synonyms: Chloroacetaldehyde
- CAS number: 107-20-0
- EC number: 203-472-8
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Do NOT induce vomiting. Refer for medical attention .
Most important symptoms/effects, acute and delayed
Poisonous; may be fatal if inhaled, swallowed or absorbed through the skin. Overexposure causes intense irritation and edema of the eyes, mucous membranes, respiratory tract, and skin. Prolonged exposure causes tissue destruction, chemical burns and residual scarring. The eyes may experience permanent damage. (USCG, 1999)
Indication of immediate medical attention and special treatment needed, if necessary
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Aldehydes and Related Compounds
SECTION 5: Firefighting measures
Suitable extinguishing media
Use water spray, powder, alcohol-resistant foam, carbon dioxide. Chloroacetaldehyde (40% Solution)
Specific hazards arising from the chemical
Special Hazards of Combustion Products: Contain poisonous and irritating chloride gases. Behavior in Fire: May yield highly toxic chloride fumes when heated to decomposition. (USCG, 1999)
Special protective actions for fire-fighters
Use water spray, powder, alcohol-resistant foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Ventilation. Collect leaking liquid in sealable containers. Wash away remainder with plenty of water.
Environmental precautions
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Ventilation. Collect leaking liquid in sealable containers. Wash away remainder with plenty of water.
Methods and materials for containment and cleaning up
Personal protection: complete protective clothing including self-contained breathing apparatus. Ventilation. Collect leaking liquid in sealable containers. Wash away remainder with plenty of water. Chloroacetaldehyde (40% Solution)
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames. NO contact with oxidizing agents or acids. Above 88°C use a closed system, ventilation and explosion-proof electrical equipment. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Separated from strong oxidants, acids, metals and food and feedstuffs.Safe Storage: Separated from strong oxidants, acids, metals and food and feedstuffs. Chloroacetaldehyde (40% Solution)
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 1 ppm as STEL.MAK: skin absorption (H); carcinogen category: 3B
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear face shield or eye protection in combination with breathing protection.
Protective gloves. Protective clothing.
Use ventilation, local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
2-chloroethanal is a clear colorless liquid with a pungent odor. Flash point about 190°F. Corrosive to skin and mucous membranes. It is very toxic by inhalation.
-
Colour：
Colorless liquid [Note: Typically found as a 40% aqueous solution]
-
Odour：
Acrid, penetrating odor
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Melting point/freezing point：
-5°C
-
Boiling point or initial boiling point and boiling range：
80-100°C(lit.)
-
Flammability：
Class IIIA Combustible Liquid: Fl.P. at or above 140°F and below 200°F.
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
62°C
-
Auto-ignition temperature：
88 deg C
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
no data available
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Solubility：
greater than or equal to 100 mg/mL at 66° F (NTP, 1992)
-
Partition coefficient n-octanol/water：
log Kow = 0.09 (est)
-
Vapour pressure：
70.6mmHg at 25°C
-
Density and/or relative density：
1.236
-
Relative vapour density：
2.7 (40% aqueous solution) (NTP, 1992) (Relative to Air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes on heating. This produces toxic fumes of chlorine. Reacts with oxidants and acids. This generates explosion hazard.
Chemical stability
The anhydrous substance polymerizes on standing, but reverts to the monomer on distillation.
Possibility of hazardous reactions
MODERATE, WHEN EXPOSED TO HEAT OR FLAMEThe vapour is heavier than air.2-CHLOROETHANAL polymerizes on standing. At greater than 50% concentration in water, it forms an insoluble hemihydrate. Sensitive to heat. Reacts with oxidizing agents. Incompatible with acids and water (NTP, 1992). Burns to give poisonous and irritating gases.
Conditions to avoid
no data available
Incompatible materials
Oxidizers, acids.
Hazardous decomposition products
When heated to decomposition it emits toxic fumes of /hydrogen chloride/.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Mouse oral 21.0 mg/kg
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
Corrosive. The vapour is corrosive to the eyes, skin and respiratory tract. Inhalation of high concentrations of the vapour may cause lung oedema. The effects may be delayed. Medical observation is indicated. See Notes.
STOT-repeated exposure
no data available
Aspiration hazard
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: no data available
- Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water Flea) age < or =24 hr; Conditions: freshwater, static, 25 deg C, pH > or = 7.0, dissolved oxygen > or =58%; Concentration: 15000 ug/L for 24 hr; Effect: intoxication, immobilization /50% purity formulation
- Toxicity to algae: EC50; Species: Scenedesmus subspicatus (Green Algae) exponential growth phase; Conditions: freshwater, static, 24 deg C, pH 8.0-9.3; Concentration: 550 ug/L for 48 hr; Effect: decreased population biomass /50% purity formulation
- Toxicity to microorganisms: no data available
Persistence and degradability
PURE CULTURE: Pseudomonas CE1r, isolated from soil, degraded 2-chloroethanol via 2-chloroacetaldehyde and 2-chloroacetate to glycollic acid(1).
Bioaccumulative potential
An estimated BCF of 3 was calculated in fish for chloroacetaldehyde(SRC), using an estimated log Kow of 0.09(1) and a regression-derived equation(1). According to a classification scheme(2), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
Using a structure estimation method based on molecular connectivity indices(1), the Koc of chloroacetaldehyde can be estimated to be 1(SRC). According to a classification scheme(2), this estimated Koc value suggests that chloroacetaldehyde is expected to have very high mobility in soil.
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN2232 (For reference only, please check.)
IMDG: UN2232 (For reference only, please check.)
IATA: UN2232 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: 2-CHLOROETHANAL (For reference only, please check.)
IMDG: 2-CHLOROETHANAL (For reference only, please check.)
IATA: 2-CHLOROETHANAL (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
This card refers to the 40% solution.The occupational exposure limit value should not be exceeded during any part of the working exposure.The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential.Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered.