Acute toxicity - Category 3, Oral
Acute toxicity - Category 3, Dermal
Carcinogenicity, Category 2
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
H301 Toxic if swallowed
H311 Toxic in contact with skin
H351 Suspected of causing cancer
H410 Very toxic to aquatic life with long lasting effects
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P203 Obtain, read and follow all safety instructions before use.
P273 Avoid release to the environment.
P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P316 Get emergency medical help immediately.
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
P318 IF exposed or concerned, get medical advice.
P391 Collect spillage.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
no data available
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Induce vomiting (ONLY IN CONSCIOUS PERSONS!). See Notes. Give a slurry of activated charcoal in water to drink. Refer for medical attention .
INHALATION AND INGESTION: These symptoms present in all affected patients - Neurologic Impairment - anxiety, irritability, memory disturbance, headache, tremors, opsiclonus, stuttering, slurred speech, and abnormal tandem gait. (USCG, 1999)
Emergency and supportive measures; 1. Maintain an open airway and assist ventilation if necessary. Administer supplemental oxygen. As most liquid products are formulated in organic solvents, observe for evidence of pulmonary aspiration. 2. Treat seizures, coma, and respiratory depression if they occur. Ventricular arrhythmias may respond to beta-adrenergic blockers such as propranolol or esmolol. 3. Attach an electrocardiographic monitor, and observe the patient for at least 6-8 hours /Chlorinated hydrocarbon pesticides/.
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
Flash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)
In case of fire in the surroundings, use appropriate extinguishing media.
Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment. Personal protection: P3 filter respirator for toxic particles.
Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment. Personal protection: P3 filter respirator for toxic particles.
Survey reports six case histories employing EPA's hazardous materials spills treatment trailer are reviewed. The trailer's ... treatment system has three mixed-media filters and three activated carbon columns to remove suspended, precipitated, and organic soluble materials. Spills of PCB, pentachlorophenol, kepone, termide (chlordane), heptachlor, aldrin, and dieldrin, toxaphene, and dinitrobutylphenol were treated by the EPA trailer, which was generally successful in mitigating environmental effects by filtering and carbon-adsorption. 90% removal was achieved for 21 of 23 compounds.
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Provision to contain effluent from fire extinguishing. Separated from acids.PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practicable to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. Chemical Carcinogens
MAK: skin absorption (H); carcinogen category: 2
no data available
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Wear face shield.
Protective clothing. Protective gloves.
Use local exhaust or breathing protection.
no data available
Kepone is an odorless colorless crystalline solid. (USCG, 1999)
Crystals
Odorless
350°C (decomp)
459.7°C at 760 mmHg
Noncombustible Solid
no data available
>100°C
no data available
no data available
no data available
no data available
less than 1 mg/mL at 73° F (NTP, 1992)
log Kow = 5.41
1.24E-08mmHg at 25°C
2.27g/cm3
16.94 (NTP, 1992) (Relative to Air)
no data available
NIOSH considers kepone to be a potential occupational carcinogen.
On combustion, forms chlorine fumes and hydrogen chloride. Decomposes on contact with acids. This produces toxic fumes.
Stable to about 350 deg C; readily hydrates on exposure to room temp & humidity
NON-FLAMMABLEA halogenated ketone. Ketones are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.
no data available
Acids, acid fumes.
Decomposes at 350 deg C.
no data available
no data available
no data available
no data available
NTP: Reasonably anticipated to be a human carcinogen
no data available
The substance may cause effects on the central nervous system and liver. This may result in impaired functions and liver impairment. The effects may be delayed.
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the endocrine system. This substance is possibly carcinogenic to humans. Causes toxicity to human reproduction or development.
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed.
AEROBIC: Kepone is not expected to be susceptible to biodegradation under aerobic conditions. An experiment using activated sludge found that <0.1% of the applied kepone was metabolised after three days(1). A similar study employed a freshwater laboratory microcosm and the results showed a half-life in estuarine sediments for kepone to be >312 days(2). In a study conducted on James River sediments with added autoclaved silty loam soil, kepone showed no degradation after 52 days at pH=7(3). Hydrosoils from a reservoir with no prior exposure to kepone and that were subsequently exposed to kepone and hydrosoils from a kepone-contaminated creek both showed no biodegradation under aerobic conditions after 56 days(4). The amount of kepone recovered from sea water under aerobic conditions for 1 year was 95%(5).
A BCF range from 900-13,500 was measured for kepone(1) using sheepshead minnows, spot fish, and oysters(1). Other reported BCFs of kepone: fathead minnow, 1,100-2,200(2); Cyprinodon variegatus, 1,548, Leiostomus xanthrus, 1,221; Palaemonetes pugio, 698, Callinectes sapidus, 8.1(4); no species reported, 8,400(3); Brevoortia tyrannus (Atlantic menhaden), 2,300-9,750; Menidia menidia (Atlantic silversides), 217,00-602,00(5). According to a classification scheme(6), these BCFs suggest that bioconcentration in aquatic organisms is high to very high(SRC).
The Koc of kepone is estimated as 21,000(SRC), using a log Kow of 5.41(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that kepone is expected to be immobile. Percent kepone leached through soil cylinders 80 cm deep: clay loam, 1.2%; clay, 17.2%; sandy clay loam, 36.8%; sandy loam, 28.1%(4).
no data available
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
ADR/RID: UN2996 (For reference only, please check.)
IMDG: UN2996 (For reference only, please check.)
IATA: UN2996 (For reference only, please check.)
ADR/RID: ORGANOCHLORINE PESTICIDE, LIQUID, TOXIC (For reference only, please check.)
IMDG: ORGANOCHLORINE PESTICIDE, LIQUID, TOXIC (For reference only, please check.)
IATA: ORGANOCHLORINE PESTICIDE, LIQUID, TOXIC (For reference only, please check.)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
ADR/RID: Yes
IMDG: Yes
IATA: Yes
no data available
no data available
Carrier solvents used in commercial formulations may change physical and toxicological properties.Do NOT take working clothes home.Consult national legislation.