Calcium arsenate SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Calcium arsenate
- CAS： 7778-44-1
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Not classified.
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Danger
H301 Toxic if swallowed
H331 Toxic if inhaled
H350 May cause cancer
H400 Very toxic to aquatic life
H410 Very toxic to aquatic life with long lasting effects
none
none
none
none
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Calcium arsenate
- Common names and synonyms: Calcium arsenate
- CAS number: 7778-44-1
- EC number: 231-904-5
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Seek medical attention if you feel unwell.
Rinse with plenty of water (remove contact lenses if easily possible). Refer for medical attention.
Rinse mouth. Refer immediately for medical attention.
Most important symptoms/effects, acute and delayed
This material is extremely toxic; the probable oral lethal dose for humans is 5-50 mg/kg, or between 7 drops and 1 teaspoonful for a 150 lb. person. It is an irritant to eyes, respiratory tract, mouth and stomach. Damage to kidneys, liver and the nervous system have been reported. (Non-Specific -- Arsenic) Chronic exposure can cause bone marrow damage, often leading to aplastic anemia. There is epidemiological evidence that chronic ingestion of arsenic compounds causes a predisposition to skin cancers. (EPA, 1998)
Indication of immediate medical attention and special treatment needed, if necessary
Following dietary admin of 215 mg/kg of diet as calcium arsenate ... for up to 52 days in rats, highest arsenic levels (146-537 ug/g dry tissue) ... in kidneys & liver & relatively lower levels in hair, brain, bone, muscle, & skin. liver & kidney levels were greater after admin of calcium arsenate than of arsenic trioxide.
SECTION 5: Firefighting measures
Suitable extinguishing media
Personnel protection: ... Wear positive pressure self contained breathing apparatus when fighting fires involving this material.
Specific hazards arising from the chemical
Fire may produce irritating or poisonous gases. When heated to decomposition, calcium arsenate produces toxic fumes of arsenic. Avoid heat. Hazardous polymerization may not occur. (EPA, 1998)
Special protective actions for fire-fighters
In case of fire in the surroundings, use appropriate extinguishing media.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Vacuum with specialist equipment (See Notes) or carefully sweep into containers. Carefully collect remainder. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Vacuum with specialist equipment (See Notes) or carefully sweep into containers. Carefully collect remainder. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Prompt cleanup and removal are necessary. Control runoff and isolate discharged material for proper disposal.
SECTION 7: Handling and storage
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Separated from acids and food and feedstuffs. Well closed. Store in an area without drain or sewer access.Long-term storage in large, weatherproof, and sift proof storage bins or silos; small amounts may be disposed in a chemical waste landfill.
SECTION 8: Exposure controls/personal protection
Control parameters
MAK: skin absorption (H); carcinogen category: 1; germ cell mutagen group: 3A
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear face shield or eye protection in combination with breathing protection.
Protective gloves. Protective clothing.
Use closed system, ventilation or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Calcium arsenate is a white powder. Slightly soluble in water. Toxic by inhalation and ingestion. Used as an insecticide and germicide.
-
Colour：
White powder
-
Odour：
Odorless
-
Melting point/freezing point：
2651° F (EPA, 1998)
-
Boiling point or initial boiling point and boiling range：
Decomposes (NIOSH, 2016)
-
Flammability：
Noncombustible Solid
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
no data available
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
no data available
-
Solubility：
0.01 % at 77° F (NIOSH, 2016)
-
Partition coefficient n-octanol/water：
no data available
-
Vapour pressure：
0 mm Hg (approx) (NIOSH, 2016)
-
Density and/or relative density：
3.62 g/cm3
-
Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
NIOSH considers calcium arsenate, as As, to be a potential occupational carcinogen.
5 mg/cu m (as AS); NIOSH considers arsenic (inorganic cmpd, as As) to be a potential occupational carcinogen. Arsenic (inorganic cmpd, as As)
Upon heating, toxic fumes are formed. Reacts with acids. This produces toxic and flammable arsine gas (See ICSC 0222).
Chemical stability
Moisture and carbon dioxide cause slow decomp to calcium carbonate and (phytotoxic) dicalcium hydrogen arsenate. In the presence of acids, water sol, strongly phytotoxic arsenic acid is produced.
Possibility of hazardous reactions
Not combustible.Has only weak oxidizing power but redox reactions can still occur. Soluble in dilute acids. [Hawley]. Produces toxic fumes of arsenic when heated to decomposition (NIOSH, 2016). Reacts with acids to produce toxic arsine gas [International Chemical Safety Card 0765].
Conditions to avoid
no data available
Incompatible materials
When water soln of arsenicals are in contact with active metals such as arsenic, iron, aluminum, zinc, ... highly toxic fumes of arsenic /including arsine are released/. arsenic cmpd
Hazardous decomposition products
When heated to decomp it emits toxic fumes of arsenic.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat female oral 298 mg/kg
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Classification of carcinogenicity: 1) evidence in humans: sufficient; 2) evidence in animals: limited. Overall summary evaluation of carcinogenic risk to humans is Group 1: Carcinogenic to humans. NOTE: This evaluation applies to the group of chemicals as a whole and not necessarily to all individual chemicals within the group. Arsenic and arsenic compounds
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes and respiratory tract. The substance may cause effects on the gastrointestinal tract. This may result in severe gastroenteritis, loss of fluids and electrolytes, cardiac disorders and shock. Exposure far above the OEL could cause death. The effects may be delayed. Medical observation is indicated.
STOT-repeated exposure
The substance may have effects on the skin, mucous membranes, peripheral nervous system, bone marrow and liver. This may result in pigmentation disorders, hyperkeratosis, perforation of the nasal septum, neuropathy, anaemia and liver impairment. This substance is carcinogenic to humans. Animal tests show that this substance possibly causes toxicity to human reproduction or development.
Aspiration hazard
A harmful concentration of airborne particles can be reached quickly when dispersed, especially if powdered.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: no data available
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
no data available
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN2759 (For reference only, please check.)
IMDG: UN2759 (For reference only, please check.)
IATA: UN2759 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: ARSENICAL PESTICIDE, SOLID, TOXIC (For reference only, please check.)
IMDG: ARSENICAL PESTICIDE, SOLID, TOXIC (For reference only, please check.)
IATA: ARSENICAL PESTICIDE, SOLID, TOXIC (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
NEVER use a domestic-type vacuum cleaner to vacuum the substance, only use specialist equipment.Depending on the degree of exposure, periodic medical examination is suggested.Do NOT take working clothes home.