Chemical Book India PDF
Chemical Safety Data Sheet MSDS / SDS

Ametryn SDS

Revision Date:2024-04-25 Revision Number:1
Section 1 Section 2 Section 3 Section 4 Section 5 Section 6 Section 7 Section 8 Section 9 Section 10 Section 11 Section 12 Section 13 Section 14 Section 15 Section 16

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: Ametryn
  • CAS: 834-12-8

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company:Chemicalbook.in
  • Address:5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
  • Telephone:+91 9550333722

SECTION 2: Hazards identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

GHS label elements, including precautionary statements

  • Pictogram(s)
  • Signal word Warning
Hazard statement(s)

H302 Harmful if swallowed

H410 Very toxic to aquatic life with long lasting effects

Precautionary statement(s)
Prevention

P264 Wash ... thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P273 Avoid release to the environment.

Response

P301+P317 IF SWALLOWED: Get medical help.

P330 Rinse mouth.

P391 Collect spillage.

Storage

none

Disposal

P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

SECTION 3: Composition/information on ingredients

Substance

  • Chemical name: Ametryn
  • Common names and synonyms: Ametryn
  • CAS number: 834-12-8
  • EC number: 212-634-7
  • Concentration: 100%

SECTION 4: First aid measures

Description of necessary first-aid measures

If inhaled

Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.

Following skin contact

Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.

Following eye contact

Rinse with pure water for at least 15 minutes. Consult a doctor.

Following ingestion

Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.

Most important symptoms/effects, acute and delayed

Excerpt from ERG Guide 151 [Substances - Toxic (Non-combustible)]: Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. (ERG, 2016)

Indication of immediate medical attention and special treatment needed, if necessary

Skin decontamination. Skin contamination should be treated promptly by washing with soap and water. Contamination of the eyes should be treated immediately by prolonged flushing of the eyes with large amounts of clean water. If dermal or ocular irritation persists, medical attention should be obtained without delay. Other herbicides

SECTION 5: Firefighting measures

Suitable extinguishing media

If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped or safely confined. Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use "alcohol" foam, carbon dioxide or dry chemical. Triazine pesticides, liquid, NOS

Specific hazards arising from the chemical

Excerpt from ERG Guide 151 [Substances - Toxic (Non-combustible)]: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Containers may explode when heated. Runoff may pollute waterways. (ERG, 2016)

Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.

Environmental precautions

Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up

For minor spills, follow all precautions indicated on this label and clean up immediately. Take special care to avoid contamination of equipment and facilities during cleanup procedures and disposal of wastes. ... Ametryn Technical

SECTION 7: Handling and storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store in cool, dry place.

SECTION 8: Exposure controls/personal protection

Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

Appropriate engineering controls

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).

Skin protection

Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.

Thermal hazards

no data available

SECTION 9: Physical and chemical properties and safety characteristics

  • Physical state:

    Solid. Powder.

  • Colour:

    White.

  • Odour:

    no data available

  • Melting point/freezing point:

    83 - 87 °C. Atm. press.:1 atm.

  • Boiling point or initial boiling point and boiling range:

    346 °C. Atm. press.:101.325 kPa.

  • Flammability:

    no data available

  • Lower and upper explosion limit/flammability limit:

    no data available

  • Flash point:

    193.5°C

  • Auto-ignition temperature:

    > 450 °C. Remarks:At atm. press. of 1.0 atm.

  • Decomposition temperature:

    no data available

  • pH:

    no data available

  • Kinematic viscosity:

    no data available

  • Solubility:

    Readily soluble in organic solvents

  • Partition coefficient n-octanol/water:

    log Pow = 3. Temperature:20 °C.

  • Vapour pressure:

    0 Pa. Temperature:20 °C.

  • Density and/or relative density:

    1 180 kg/m3. Temperature:22 °C.

  • Relative vapour density:

    no data available

  • Particle characteristics:

    no data available

SECTION 10: Stability and reactivity

Reactivity

No rapid reaction with air. No rapid reaction with water.

Chemical stability

Very stable over several yr of shelf life & only slight sensitivity to natural light & extreme temperatures.

Possibility of hazardous reactions

Nonflammable.An amine, organosulfide. Organosulfides are incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas. Many of these compounds may liberate hydrogen sulfide upon decomposition or reaction with an acid. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Conditions to avoid

no data available

Incompatible materials

no data available

Hazardous decomposition products

When heated to decomposition it emits very toxic fumes of /nitrogen and sulfur oxides/.

SECTION 11: Toxicological information

Acute toxicity

  • Oral: LD50 Rat oral 1100 mg/kg Technical
  • Inhalation: LC50 Rat (albino) inhalation >27 mg/L/4 hr
  • Dermal: LD50 Rat percutaneous > 3100 mg/kg

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

Cancer Classification: Data are Inadequate for an Assessment of Human Carcinogenic Potential

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

SECTION 12: Ecological information

Toxicity

  • Toxicity to fish: LC50 - Oncorhynchus mykiss (previous name: Salmo gairdneri) - 5.9 mg/L - 96 h.
  • Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - > 15 mg/L - 48 h.
  • Toxicity to algae: EC50 - Desmodesmus subspicatus (previous name: Scenedesmus subspicatus) - 0.003 mg/L - 72 h.
  • Toxicity to microorganisms: EC50 - activated sludge of a predominantly domestic sewage - > 1 000 mg/L - 3 h.

Persistence and degradability

AEROBIC: Several soil bacteria and fungi are reported to attack ametryne(1). The methylthio group is known to undergo sulfoxidation by microsomal enzymes in plant and animal systems and the same reactions usually hold true for soil microorganisms(1). Methylthio-s-triazine herbicides are generally more resistant to biodegradation than the corresponding chloro-s-triazines(1). No biodegradation was observed when 200 ppm of ametryne was incubated for a month using a soil suspension inoculum at 30 deg C(2). When the concn equivalent of 3 kg/ha of ametryne was incubated in a clay-lime soil, 2.8% and 8.6% of the herbicide degraded to CO2 in 51 and 110 days, respectively(2). In another experiment, 10-50% degradation in 10 days occurred in one of four soils, while degradation was either absent or uncertain in the other three soils(3). In a 25-day experiment, CO2 evolution occurred from ametryne-treated sterile soil that had been inoculated with an extract from ametryne enriched soil, but not from uninoculated controls(1). After 60 days incubation, 8.7% and 63.7% of the applied ametryne remained in inoculated Hilo silty clay loam and Molakai silty clay, two Hawaiian soils that are typically used in the cultivation of sugarcane(4). The inoculum was prepared by leaching Molakai soil with ametryne solutions(4). Biodegradation initially involved N-dealkylation. Less than 0.2% of the ametryne degraded to CO2 in this period(4). No significant degradation occurred in autoclaved controls(4). Ametryne has been shown to be susceptible to degradation by Nocardiodes sp.(5).

Bioaccumulative potential

An estimated BCF of 19 was calculated in fish for ametryne(SRC), using a log Kow of 2.98(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

Mobility in soil

The average Koc reported for ametryne in 32 soils was 388.4(1). Ametryne has a Koc value of 300(2). Mean overall Koc values measured in four Hawaiian soils were 257 for surface soil (0 to 20 cm) and 170 for subsoil (60 to 80 cm); Kocs of 530, 170, 156, and 171 were measured in the surface soil of Torrox (mean % OC 1.30, pH 6.7), Eustrustox (mean OC 1.63%, pH 6.4), Tropohumult (mean OC% 2.88, pH 5.3), and Hydrandept (mean OC% 6.22, pH 5.3); Kocs of 235, 254, 87, and 107 were measured in subsoil of Torrox (mean OC% 0.55, pH 6.8), Eustrustox (mean OC% 0.76, pH 5.7), Tropohumult (mean OC% 1.51, pH 5.3), and Hydrandept (mean OC% 3.19, pH 5.6)(3). Koc values were measured for two Kishon River sediments; Kfar Yehushua was 69.33 (7.1 pH, 30% sand, 30% silt 40% clay 1.63% TOC) and Haifa industrial area was 170.40 (6.8 pH, 30 % sand, 20% silt, 50% clay, 1.25% TOC)(4). Koc values ranged from 102-123 in fresh soils amended with activated sludge, anaerobic digested sludge and compost, and 69-129 in incubated soils with the same amendments(5). According to a classification scheme(6), these Koc values suggest that ametryne is expected to have moderate to high mobility in soil(SRC). Of 38 values sited in literature the mean Kd is 5.69(7).

Other adverse effects

no data available

SECTION 13: Disposal considerations

Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

SECTION 14: Transport information

UN Number

ADR/RID: Not dangerous goods. (For reference only, please check.)

IMDG: Not dangerous goods. (For reference only, please check.)

IATA: Not dangerous goods. (For reference only, please check.)

UN Proper Shipping Name

ADR/RID: Not dangerous goods. (For reference only, please check.)

IMDG: Not dangerous goods. (For reference only, please check.)

IATA: Not dangerous goods. (For reference only, please check.)

Transport hazard class(es)

ADR/RID: Not dangerous goods. (For reference only, please check.)

IMDG: Not dangerous goods. (For reference only, please check.)

IATA: Not dangerous goods. (For reference only, please check.)

Packing group, if applicable

ADR/RID: Not dangerous goods. (For reference only, please check.)

IMDG: Not dangerous goods. (For reference only, please check.)

IATA: Not dangerous goods. (For reference only, please check.)

Environmental hazards

ADR/RID: Yes

IMDG: Yes

IATA: Yes

Special precautions for user

no data available

Transport in bulk according to IMO instruments

no data available

SECTION 15: Regulatory information

Safety, health and environmental regulations specific for the product in question

European Inventory of Existing Commercial Chemical Substances (EINECS)
Listed.
EC Inventory
Listed.
United States Toxic Substances Control Act (TSCA) Inventory
Not Listed.
China Catalog of Hazardous chemicals 2015
Not Listed.
New Zealand Inventory of Chemicals (NZIoC)
Listed.
(PICCS)
Listed.
Vietnam National Chemical Inventory
Listed.
IECSC)
Not Listed.
Korea Existing Chemicals List (KECL)
Not Listed.

SECTION 16: Other information

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%

References

  • IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
  • HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
  • IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
  • CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
  • ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
  • Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
  • ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any