Chemical Book India PDF
Chemical Safety Data Sheet MSDS / SDS

Ascorbic acid SDS

Revision Date:2024-04-25 Revision Number:1
Section 1 Section 2 Section 3 Section 4 Section 5 Section 6 Section 7 Section 8 Section 9 Section 10 Section 11 Section 12 Section 13 Section 14 Section 15 Section 16

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: Ascorbic acid
  • CAS: 50-81-7

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company:Chemicalbook.in
  • Address:5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
  • Telephone:+91 9550333722

SECTION 2: Hazards identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

  • Signal word No signal word
Hazard statement(s)

none

Precautionary statement(s)
Prevention

none

Response

none

Storage

none

Disposal

none

Other hazards which do not result in classification

no data available

SECTION 3: Composition/information on ingredients

Substance

  • Chemical name: Ascorbic acid
  • Common names and synonyms: Ascorbic acid
  • CAS number: 50-81-7
  • EC number: 200-066-2
  • Concentration: 100%

SECTION 4: First aid measures

Description of necessary first-aid measures

If inhaled

Fresh air, rest.

Following skin contact

Remove contaminated clothes. Rinse skin with plenty of water or shower.

Following eye contact

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Following ingestion

Rinse mouth.

Most important symptoms/effects, acute and delayed

SYMPTOMS: Symptoms of exposure to this compound may include irritation of the skin, eyes and respiratory tract. Ingestion of large amounts may cause gastrointestinal distress and diarrhea. Exposure may also cause the formation of renal calcium oxalate calculi. There have been cases of allergic reaction with eczema, urticaria and asthma. The mucolytic effect of this compound might render the cervical mucus less permeable to spermatozoa. ACUTE/CHRONIC HAZARDS: This compound may cause irritation of the skin, eyes and respiratory tract. When heated to decomposition it emits acrid smoke and irritating fumes. (NTP, 1992)

Indication of immediate medical attention and special treatment needed, if necessary

All sources of vitamin C should be withdrawn and treatment for gastrointestinal symptoms provided, including antiemetics. If significant hemolysis occurs, intravenous hydration to maintain urine output should be administered. Monitoring renal function should be performed, and rarely, transfusion of packed red blood cells is required.

SECTION 5: Firefighting measures

Suitable extinguishing media

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used. (NTP, 1992)

Specific hazards arising from the chemical

Flash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)

Special protective actions for fire-fighters

Use water spray, powder.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water.

Environmental precautions

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water.

Methods and materials for containment and cleaning up

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

SECTION 7: Handling and storage

Precautions for safe handling

NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Separated from strong oxidants and strong bases.Solutions of ascorbic acid are rapidly oxidized in air and in alkaline media; the drug should be protected from air and light.

SECTION 8: Exposure controls/personal protection

Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

Appropriate engineering controls

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Wear safety spectacles.

Skin protection

Protective gloves.

Respiratory protection

Use local exhaust or breathing protection.

Thermal hazards

no data available

SECTION 9: Physical and chemical properties and safety characteristics

  • Physical state:

    PHYSICAL DESCRIPTION: White to very pale yellow crystalline powder with a pleasant sharp acidic taste. Almost odorless. (NTP, 1992)

  • Colour:

    Crystals (usually plates, sometimes needles, monoclinic system)

  • Odour:

    Odorless

  • Melting point/freezing point:

    192°C(lit.)

  • Boiling point or initial boiling point and boiling range:

    83°C/44mmHg(lit.)

  • Flammability:

    Combustible.

  • Lower and upper explosion limit/flammability limit:

    no data available

  • Flash point:

    15°C(lit.)

  • Auto-ignition temperature:

    1220° F (NTP, 1992)

  • Decomposition temperature:

    190-192°C

  • pH:

    Between 2,4 and 2,8 (2?% aqueous solution)

  • Kinematic viscosity:

    no data available

  • Solubility:

    greater than or equal to 100 mg/mL at 73° F (NTP, 1992)

  • Partition coefficient n-octanol/water:

    -2.15

  • Vapour pressure:

    9.28X10-11 mm Hg at 25 deg C (est)

  • Density and/or relative density:

    1.7

  • Relative vapour density:

    no data available

  • Particle characteristics:

    no data available

SECTION 10: Stability and reactivity

Reactivity

The substance is a strong reducing agent. It reacts violently with oxidants. The solution in water is a medium strong acid.

Chemical stability

Stable to air when dry; impure preparation and in many natural products vitamin oxidizes on exposure to air and light. Aqueous solutions are rapidly oxidized by air, accelerated by alkalies, iron, copper

Possibility of hazardous reactions

L-ASCORBIC ACID is a lactone. Reacts as a relatively strong reducing agent and decolorizes many dyes. Forms stable metal salts. Incompatible with oxidizers, dyes, alkalis, iron and copper. Also incompatible with ferric salts and salts of heavy metals, particularly copper, zinc and manganese (NTP, 1992).

Conditions to avoid

no data available

Incompatible materials

no data available

Hazardous decomposition products

When heated to decomposition it emits acrid smoke and irritating fumes.

SECTION 11: Toxicological information

Acute toxicity

  • Oral: LD50 Rat oral 11,900 mg/kg
  • Inhalation: no data available
  • Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

no data available

Reproductive toxicity

no data available

STOT-single exposure

The substance is irritating to the eyes, skin and respiratory tract.

STOT-repeated exposure

no data available

Aspiration hazard

No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20°C.

SECTION 12: Ecological information

Toxicity

  • Toxicity to fish: LC50 Species: /Oncorhynchus mykiss/ (Rainbow trout); Concentration: 1,020 mg/L for 96 hr /Conditions of bioassay not specified in source examined
  • Toxicity to daphnia and other aquatic invertebrates: no data available
  • Toxicity to algae: no data available
  • Toxicity to microorganisms: no data available

Persistence and degradability

AEROBIC: Using a mixed microbial consortia enriched from untreated sewage samples collected in the vicinity of a primary treatment plant in Delhi, India, L-ascorbic acid exhibited 36.7 mg/L BOD, suggesting moderate susceptibility to biodegradation(1).

Bioaccumulative potential

An estimated BCF of 3 was calculated in fish for L-ascorbic acid(SRC), using a log Kow of -1.85(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

Mobility in soil

The Koc of L-ascorbic acid is estimated as 10(SRC), using a log Kow of -1.85(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that L-ascorbic acid is expected to have very high mobility in soil. The pKa of L-ascorbic acid is 4.70(4), indicating that this compound will exist almost entirely in the anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(5).

Other adverse effects

no data available

SECTION 13: Disposal considerations

Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

SECTION 14: Transport information

UN Number

ADR/RID: Not dangerous goods. (For reference only, please check.)

IMDG: Not dangerous goods. (For reference only, please check.)

IATA: Not dangerous goods. (For reference only, please check.)

UN Proper Shipping Name

ADR/RID: Not dangerous goods. (For reference only, please check.)

IMDG: Not dangerous goods. (For reference only, please check.)

IATA: Not dangerous goods. (For reference only, please check.)

Transport hazard class(es)

ADR/RID: Not dangerous goods. (For reference only, please check.)

IMDG: Not dangerous goods. (For reference only, please check.)

IATA: Not dangerous goods. (For reference only, please check.)

Packing group, if applicable

ADR/RID: Not dangerous goods. (For reference only, please check.)

IMDG: Not dangerous goods. (For reference only, please check.)

IATA: Not dangerous goods. (For reference only, please check.)

Environmental hazards

ADR/RID: No

IMDG: No

IATA: No

Special precautions for user

no data available

Transport in bulk according to IMO instruments

no data available

SECTION 15: Regulatory information

Safety, health and environmental regulations specific for the product in question

European Inventory of Existing Commercial Chemical Substances (EINECS)
Listed.
EC Inventory
Listed.
United States Toxic Substances Control Act (TSCA) Inventory
Listed.
China Catalog of Hazardous chemicals 2015
Not Listed.
New Zealand Inventory of Chemicals (NZIoC)
Listed.
(PICCS)
Listed.
Vietnam National Chemical Inventory
Listed.
IECSC)
Listed.
Korea Existing Chemicals List (KECL)
Listed.

SECTION 16: Other information

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%

References

  • IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
  • HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
  • IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
  • CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
  • ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
  • Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
  • ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any