Acute toxicity - Category 4, Oral
Skin irritation, Category 2
Skin sensitization, Category 1
Eye irritation, Category 2
Germ cell mutagenicity, Category 2
Specific target organ toxicity – repeated exposure, Category 2
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
H302 Harmful if swallowed
H315 Causes skin irritation
H317 May cause an allergic skin reaction
H319 Causes serious eye irritation
H341 Suspected of causing genetic defects
H373 May cause damage to organs through prolonged or repeated exposure
H410 Very toxic to aquatic life with long lasting effects
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P203 Obtain, read and follow all safety instructions before use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P273 Avoid release to the environment.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P333+P317 If skin irritation or rash occurs: Get medical help.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P318 IF exposed or concerned, get medical advice.
P319 Get medical help if you feel unwell.
P391 Collect spillage.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
no data available
Fresh air, rest.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Give one or two glasses of water to drink.
Excerpt from ERG Guide 149 [Substances (Self-Reactive)]: Inhalation or contact with vapors, substance or decomposition products may cause severe injury or death. May produce irritating, toxic and/or corrosive gases. Runoff from fire control may cause pollution. (ERG, 2016)
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Organic acids and related compounds
In case of fire in the surroundings: use appropriate extinguishing media.
Excerpt from ERG Guide 149 [Substances (Self-Reactive)]: Self-decomposition, self-polymerization, or self-ignition may be triggered by heat, chemical reaction, friction or impact. May be ignited by heat, sparks or flames. Some may decompose explosively when heated or involved in a fire. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. May burn violently. Decomposition or polymerization may be self-accelerating and produce large amounts of gases. Vapors or dust may form explosive mixtures with air. (ERG, 2016)
In case of fire in the surroundings, use appropriate extinguishing media.
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Personal protection: particulate filter respirator adapted to the airborne concentration of the substance.
Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place.
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
TLV: (inhalable fraction): 0.1 mg/m3, as TWA
no data available
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Wear safety spectacles.
Protective gloves.
Use local exhaust.
no data available
Diphenyloxide-4,4'-disulfonyl hydrazide is a colorless, crystalline solid with a geranium-like odor. Insoluble in water and denser than water. Contact may irritate skin, eyes and mucous membranes. Moderately toxic by ingestion, inhalation and skin absorption. Readily ignited by sparks or flames and burns intensely and persistently.
Fine white crystalline powder
Odorless
155 °C. Remarks:Data from handbook or collection of data.
140°C (Decomposes)
Not combustible.
no data available
159°C
no data available
140-160°C
no data available
no data available
Soluble in acetone; moderately soluble in ethanol and polyethylene glycols; insoluble in water and gasoline
log Pow = 0.08. Remarks:Based on smiles code.
<= 0 hPa. Temperature:Ca. 80 °C. Remarks:Limit value calculated based on the detection limit of HPLC.
>= 1.52 g/cm3. Temperature:20 °C.
no data available
no data available
no data available
no data available
Not combustible.DIPHENYLOXIDE-4,4'-DISULFOHYDRAZIDE is an azide. Azo, diazo, azido compounds can detonate. This applies in particular to organic azides that have been sensitized by the addition of metal salts or strong acids. Toxic gases are formed by mixing materials of this class with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. Flammable gases are formed by mixing materials in this group with alkali metals. Explosive combination can occur with strong oxidizing agents, metal salts, peroxides, and sulfides.
no data available
no data available
When heated to decomposition it emits very toxic fumes of /nitroxides/ and /sulfoxides/.
no data available
no data available
no data available
no data available
no data available
no data available
See Notes.
no data available
Evaporation at 20°C is negligible; a nuisance-causing concentration of airborne particles can, however, be reached quickly when dispersed.
AEROBIC: p,p'-Oxybis(benzenesulfonyl hydrazide), present at 100 ppm, reached 2% of its theoretical BOD in 2 weeks using an activated sludge inoculum at 30 ppm in the Japanese MITI test(1,2), indicating that biodegradation is not expected to be an important environmental fate process(SRC).
BCF values of <0.3 and <3.0 were calculated in carp (Cyprinus carpio) for p,p'-oxybis(benzenesulfonyl hydrazide), exposed over a 6 week test period to 1 mg/L and 0.1 mg/L, respectively(1). According to a classification scheme(2), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Using a structure estimation method based on molecular connectivity indices(1), the Koc of p,p'-oxybis(benzenesulfonyl hydrazide) can be estimated to be 880(SRC). According to a classification scheme(2), this estimated Koc value suggests that p,p'-oxybis(benzenesulfonyl hydrazide) is expected to have low mobility in soil.
no data available
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
ADR/RID: UN3226 (For reference only, please check.)
IMDG: UN3226 (For reference only, please check.)
IATA: UN3226 (For reference only, please check.)
ADR/RID: SELF-REACTIVE SOLID TYPE D (For reference only, please check.)
IMDG: SELF-REACTIVE SOLID TYPE D (For reference only, please check.)
IATA: SELF-REACTIVE SOLID TYPE D (For reference only, please check.)
ADR/RID: 4.1 (For reference only, please check.)
IMDG: 4.1 (For reference only, please check.)
IATA: 4.1 (For reference only, please check.)
ADR/RID: (For reference only, please check.)
IMDG: (For reference only, please check.)
IATA: (For reference only, please check.)
ADR/RID: Yes
IMDG: Yes
IATA: Yes
no data available
no data available
Health effects of exposure to the substance have not been investigated adequately.