Carcinogenicity, Category 1B
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2
H350 May cause cancer
H411 Toxic to aquatic life with long lasting effects
P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P273 Avoid release to the environment.
P318 IF exposed or concerned, get medical advice.
P391 Collect spillage.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
no data available
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Refer for medical attention .
Exposure Routes: inhalation, skin absorption, ingestion, skin and/or eye contact Symptoms: Headache, drowsiness, dizziness; dyspnea (breathing difficulty); ataxia, lassitude (weakness, exhaustion); methemoglobinemia; urinary burning; acute hemorrhagic cystitis; [potential occupational carcinogen] Target Organs: Bladder, blood (NIOSH, 2016)
4-nitrodiphenyl ... known to readily penetrate intact skin.
Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: SMALL FIRE: Dry chemical, CO2 or water spray. LARGE FIRE: Dry chemical, CO2, alcohol-resistant foam or water spray. Move containers from fire area if you can do it without risk. Dike fire-control water for later disposal; do not scatter the material. FIRE INVOLVING TANKS OR CAR/TRAILER LOADS: Fight fire from maximum distance or use unmanned hose holders or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks engulfed in fire. (ERG, 2016)
Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. For electric vehicles or equipment, ERG Guide 147 (lithium ion batteries) or ERG Guide 138 (sodium batteries) should also be consulted. (ERG, 2016)
Use water spray.
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. Carefully collect remainder. Then store and dispose of according to local regulations.
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. Carefully collect remainder. Then store and dispose of according to local regulations.
Research program was conducted to determine the capability of biol treatment and activated carbon adsorption to remove chem carcinogens from water and wastewater. cmpd studied incl 4-nitrobiphenyl. all cmpd tested exhibited some deg of biol degradation. carbon adsorption was also effective in removing the cmpd from aq soln.
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Separated from strong reducing agents. Well closed.
TLV: (skin); A2 (suspected human carcinogen).MAK: skin absorption (H); carcinogen category: 2
no data available
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Wear safety spectacles or eye protection in combination with breathing protection if powder.
Protective gloves. Protective clothing.
Use local exhaust or breathing protection.
no data available
4-nitrobiphenyl is a white to yellow needle-like crystalline solid with a sweetish odor. (NIOSH, 2016)
YELLOW NEEDLES FROM ALC
SWEETISH ODOR
114°C
340°C
Combustible Solid
no data available
43°C
no data available
no data available
no data available
no data available
Insoluble (NIOSH, 2016)
log Kow= 3.77 (est)
no data available
1.328
no data available
no data available
NIOSH has recommended that 4-nitrobiphenyl be treated as a potential human carcinogen.
Decomposes on burning. This produces toxic gases. Reacts with strong reducing agents. This generates toxic hazard.
no data available
4-NITROBIPHENYL is incompatible with the following: Strong reducers (NIOSH, 2016).
no data available
Strong reducers.
When heated to decomp it emits toxic fumes of /nitrogen oxides/.
no data available
no data available
no data available
no data available
No data are available in humans. Inadequate evidence of carcinogenicity in animals. OVERALL EVALUATION: Group 3: The agent is not classifiable as to its carcinogenicity to humans.
No information is available on the reproductive or developmental effects of 4-nitrobiphenyl in humans or animals.
The substance is irritating to the eyes.
This substance is probably carcinogenic to humans.
A harmful concentration of airborne particles can be reached quickly when dispersed, especially if powdered.
p-Nitrobiphenyl exhibited fast biodegradation with rapid adaptation using a static-culture screening procedure with a settled domestic wastewater microbial inocula(1); degradation was determined to be 97.5% after 7 days of incubation(1).
Based upon an estimated log Kow of 3.77(1), the BCF for p-nitrobiphenyl can be estimated to be 432 from a recommended regression equation(2,SRC). This estimated BCF value suggests that moderate bioconcentration may occur(SRC).
Based upon an estimated log Kow of 3.77(1), the Koc for p-nitrobiphenyl can be estimated to range from 2680 to 3360 using various regression-derived equations(2,SRC). These Koc estimates indicate very low soil mobility(3).
no data available
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
ADR/RID: UN3077 (For reference only, please check.)
IMDG: UN3077 (For reference only, please check.)
IATA: UN3077 (For reference only, please check.)
ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.)
IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.)
IATA: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.)
ADR/RID: 9 (For reference only, please check.)
IMDG: 9 (For reference only, please check.)
IATA: 9 (For reference only, please check.)
ADR/RID: III (For reference only, please check.)
IMDG: III (For reference only, please check.)
IATA: III (For reference only, please check.)
ADR/RID: Yes
IMDG: Yes
IATA: Yes
no data available
no data available
Similar substances have caused methemoglobinemia, but there are no data available for this substance.Depending on the degree of exposure, periodic medical examination is suggested.Do NOT take working clothes home.TLV Note: Exposure by all routes should be carefully controlled to levels as low as possible.