Chemical Book India PDF
Chemical Safety Data Sheet MSDS / SDS

4-methylpentan-2-ol SDS

Revision Date:2024-04-25 Revision Number:1
Section 1 Section 2 Section 3 Section 4 Section 5 Section 6 Section 7 Section 8 Section 9 Section 10 Section 11 Section 12 Section 13 Section 14 Section 15 Section 16

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: 4-methylpentan-2-ol
  • CAS: 108-11-2

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company:Chemicalbook.in
  • Address:5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
  • Telephone:+91 9550333722

SECTION 2: Hazards identification

Classification of the substance or mixture

Flammable liquids, Category 3

Specific target organ toxicity – single exposure, Category 3

GHS label elements, including precautionary statements

  • Pictogram(s)
  • Signal word Warning
Hazard statement(s)

H226 Flammable liquid and vapour

H335 May cause respiratory irritation

Precautionary statement(s)
Prevention

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.

P233 Keep container tightly closed.

P240 Ground and bond container and receiving equipment.

P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment.

P242 Use non-sparking tools.

P243 Take action to prevent static discharges.

P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

P271 Use only outdoors or in a well-ventilated area.

Response

P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse affected areas with water [or shower].

P370+P378 In case of fire: Use ... to extinguish.

P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P319 Get medical help if you feel unwell.

Storage

P403+P235 Store in a well-ventilated place. Keep cool.

P403+P233 Store in a well-ventilated place. Keep container tightly closed.

P405 Store locked up.

Disposal

P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

SECTION 3: Composition/information on ingredients

Substance

  • Chemical name: 4-methylpentan-2-ol
  • Common names and synonyms: 4-methylpentan-2-ol
  • CAS number: 108-11-2
  • EC number: 203-551-7
  • Concentration: 100%

SECTION 4: First aid measures

Description of necessary first-aid measures

If inhaled

Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.

Following skin contact

Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .

Following eye contact

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Following ingestion

Rinse mouth. Rest. Refer for medical attention .

Most important symptoms/effects, acute and delayed

Vapor irritates eyes and nose; may cause anesthesia. Prolonged contact with liquid causes irritation and cracking of skin; also irritates eyes. (USCG, 1999)

Indication of immediate medical attention and special treatment needed, if necessary

no data available

SECTION 5: Firefighting measures

Suitable extinguishing media

Alcohol foam.

Specific hazards arising from the chemical

Excerpt from ERG Guide 129 [Flammable Liquids (Water-Miscible / Noxious)]: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water. (ERG, 2016)

Special protective actions for fire-fighters

Use water spray, powder, alcohol-resistant foam, carbon dioxide.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer.

Environmental precautions

Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer.

Methods and materials for containment and cleaning up

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

SECTION 7: Handling and storage

Precautions for safe handling

NO open flames, NO sparks and NO smoking. Above 41°C use a closed system, ventilation and explosion-proof electrical equipment. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Fireproof if in building. Separated from strong oxidants. Cool.

SECTION 8: Exposure controls/personal protection

Control parameters

Occupational Exposure limit values

TLV: 25 ppm as TWA; 40 ppm as STEL; (skin).MAK: 85 mg/m3, 20 ppm; peak limitation category: I(1); pregnancy risk group: D

Biological limit values

no data available

Appropriate engineering controls

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Wear safety goggles.

Skin protection

Protective gloves. Protective clothing.

Respiratory protection

Use ventilation, local exhaust or breathing protection.

Thermal hazards

no data available

SECTION 9: Physical and chemical properties and safety characteristics

  • Physical state:

    Liquid.

  • Colour:

    COLORLESS LIQ

  • Odour:

    Mild odor.

  • Melting point/freezing point:

    -90 °C.

  • Boiling point or initial boiling point and boiling range:

    132 °C. Atm. press.:1 013 hPa.

  • Flammability:

    Class II Combustible Liquid: Fl.P. at or above 100°F and below 140°F.

  • Lower and upper explosion limit/flammability limit:

    no data available

  • Flash point:

    41 °C. Atm. press.:Not reported.

  • Auto-ignition temperature:

    335°C. Atm. press.:Not reported.

  • Decomposition temperature:

    no data available

  • pH:

    no data available

  • Kinematic viscosity:

    dynamic viscosity (in mPa s) = 4.074. Temperature:25.0°C.

  • Solubility:

    2 % (NIOSH, 2016)

  • Partition coefficient n-octanol/water:

    log Pow = 1.9.;Pow = 79.

  • Vapour pressure:

    1 Pa. Temperature:-43 °C.;10 Pa. Temperature:-24 °C.;100 Pa. Temperature:0 °C.

  • Density and/or relative density:

    0.81 g/cm3. Temperature:20 °C.

  • Relative vapour density:

    3.5 (vs air)

  • Particle characteristics:

    no data available

SECTION 10: Stability and reactivity

Reactivity

Reacts with strong oxidants.

Chemical stability

Stable liq

Possibility of hazardous reactions

MODERATE FIRE RISK.The vapour is heavier than air and may travel along the ground; distant ignition possible.METHYL ISOBUTYL CARBINOL is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides. This compound is incompatible with strong oxidizers (NIOSH, 2016).

Conditions to avoid

no data available

Incompatible materials

Strong oxidizers.

Hazardous decomposition products

no data available

SECTION 11: Toxicological information

Acute toxicity

  • Oral: LD50 Rat oral 2.6 g/kg
  • Inhalation: LC50 - rat (male/female) - > 16 000 mg/m3 air (nominal).
  • Dermal: LD50 - rabbit - 3.56 mL/kg body weight.

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

no data available

Reproductive toxicity

no data available

STOT-single exposure

The substance is irritating to the eyes, skin and respiratory tract. Exposure could cause lowering of consciousness.

STOT-repeated exposure

The substance defats the skin, which may cause dryness or cracking.

Aspiration hazard

A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C.

SECTION 12: Ecological information

Toxicity

  • Toxicity to fish: LC50 - Pimephales promelas - > 92.4 mg/L - 96 h.
  • Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - 337 mg/L - 48 h.
  • Toxicity to algae: EC50 - Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum) - 147 mg/L - 72 h.
  • Toxicity to microorganisms: EC50 - activated sludge of a predominantly domestic sewage - > 100 mg/L - 3 h. Remarks:Respiration rate.

Persistence and degradability

A percent theoretical BOD of 84% was observed after 5 days in screening tests using the standard dilution technique and effluent from a biological sanitary waste treatment plant as inoculum(1). A percent theoretical BOD of 43% was observed after 5 days in screening tests using the standard dilution technique and acclimated sewage as inoculum(2). Tests using acclimated mixed microbial cultures as inoculum gave a percent theoretical BOD of 56% after 5 days(3). In screening tests using filtered, settled domestic wastewater as inoculum, the observed percent theoretical BOD of 50%, 72%, 90% and 94% were observed after 5, 10, 15, 20 days, respectively(4). In screening tests using activated sludge in a medium containing 100 ppm urea and approximately 16,000 ppm ethyl alcohol, the observed rate constant of disappearance of 4-methyl-2-pentanol was 0.432/hr which corresponds to a half-life of 17 hr(5). The results of these laboratory screening tests indicate that 4-methyl-2-pentanol is readily biodegradable under the conditions used in the experiments(SRC). No information regarding biodegradation in natural media was found(SRC).

Bioaccumulative potential

Based upon an experimental log Kow of 1.43(1), a BCF of 7.2 has been estimated using a recommended regression equation(2). Based upon an experimental water solubility of 1.64X10+4 mg/kg(3), a BCF of 2.6 has been estimated using a recommended regression equation(2). Based upon these estimated BCF, 4-methyl-2-pentanol will not be expected to bioconcentrate in aquatic organisms(SRC).

Mobility in soil

Based upon an experimental log Kow of 1.43(1), a Koc of 143 has been estimated using a recommended regression equation(2). Based upon an experimental water solubility of 1.64X10+4 mg/kg(3), a Koc of 21 has been estimated using a recommended regression equation(2). Based upon these estimated Koc, 4-methyl-2-pentanol will be expected to exhibit high to very high mobility in soil(4). 4-Methyl-2-pentanol, therefore, may leach through soil to groundwater if it does not volatilize or biodegrade first(SRC).

Other adverse effects

no data available

SECTION 13: Disposal considerations

Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

SECTION 14: Transport information

UN Number

ADR/RID: UN2053 (For reference only, please check.)

IMDG: UN2053 (For reference only, please check.)

IATA: UN2053 (For reference only, please check.)

UN Proper Shipping Name

ADR/RID: METHYL ISOBUTYL CARBINOL (For reference only, please check.)

IMDG: METHYL ISOBUTYL CARBINOL (For reference only, please check.)

IATA: METHYL ISOBUTYL CARBINOL (For reference only, please check.)

Transport hazard class(es)

ADR/RID: 3 (For reference only, please check.)

IMDG: 3 (For reference only, please check.)

IATA: 3 (For reference only, please check.)

Packing group, if applicable

ADR/RID: III (For reference only, please check.)

IMDG: III (For reference only, please check.)

IATA: III (For reference only, please check.)

Environmental hazards

ADR/RID: No

IMDG: No

IATA: No

Special precautions for user

no data available

Transport in bulk according to IMO instruments

no data available

SECTION 15: Regulatory information

Safety, health and environmental regulations specific for the product in question

European Inventory of Existing Commercial Chemical Substances (EINECS)
Listed.
EC Inventory
Listed.
United States Toxic Substances Control Act (TSCA) Inventory
Listed.
China Catalog of Hazardous chemicals 2015
Listed.
New Zealand Inventory of Chemicals (NZIoC)
Listed.
(PICCS)
Listed.
Vietnam National Chemical Inventory
Listed.
IECSC)
Listed.
Korea Existing Chemicals List (KECL)
Listed.

SECTION 16: Other information

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%

References

  • IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
  • HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
  • IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
  • CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
  • ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
  • Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
  • ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any