Acute toxicity - Category 4, Oral
Skin irritation, Category 2
Eye irritation, Category 2
H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
none
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
no data available
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
Rinse with plenty of water (remove contact lenses if easily possible).
Rinse mouth. Refer for medical attention .
SYMPTOMS: Symptoms of exposure to this compound include painless blanching or erythema, vomiting, collapse, coma, profuse sweating, intense thirst, nausea, diarrhea, cyanosis, hyperactivity, stupor, blood pressure fall, hyperpnea, abdominal pain, hemolysis, convulsions and pulmonary edema followed by pneumonia. Other symptoms include irritation of the skin with redness and edema, eye irritation, corneal injury and iritis. The dusts cause irritation of the nose and pharynx. Exposure can cause irritation of the mucous membranes and respiratory tract, severe destruction of tissue (due to intensity and duration of exposure) and burns. Symptoms of exposure to a related compound include softening and whitening of the skin followed by development of painful burns, headache, dizziness, rapid and difficult breathing and weakness. Ingestion of a related compound causes severe burns and internal damage. Chronic exposure causes digestive disturbances, nervous disorders, skin eruptions, dermatitis, liver damage and kidney damage. ACUTE/CHRONIC HAZARDS: This compound may be harmful by inhalation or ingestion. It is an irritant of the skin, eyes, mucous membranes and upper respiratory tract. Prolonged contact may result in severe burns and destruction of tissue. When heated to decomposition it emits toxic fumes of carbon monoxide, carbon dioxide and hydrogen chloride gas. (NTP, 1992)
For advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious or in respiratory arrest. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias if necessary . Start an IV with D5W TKO /SRP: To keep open, "minimal flow rate"/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema . For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors for hypotension with a normal fluid volume. Watch for signs of fluid overload . Administer 1% solution methylene blue if patient is symptomatic with severe hypoxia, cyanosis, and cardiac compromise not responding to oxygen. . Treat seizures with diazepam (Valium). ... Use proparacaine hydrochloride to assist eye irrigation . Phenols and related compounds
Extinguish fire using agent suitable for type of surrounding fire. Material itself does not burn or burns with difficulty. Trichlorophenol
This chemical is combustible. (NTP, 1992)
Use foam, dry powder, carbon dioxide.
Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Land Spill: Dig a pit, pond, lagoon, or holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner./ Cover solids with plastic sheet to prevent dissolving in rain or fire fighting water. Trichlorophenol
NO open flames. Above 79°C use a closed system and ventilation. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing. Separated from strong oxidants and food and feedstuffs.
Component | 2,3,6-trichlorophenol | |||
---|---|---|---|---|
CAS No. | 933-75-5 | |||
Limit value - Eight hours | Limit value - Short term | |||
ppm | mg/m3 | ppm | mg/m3 | |
Denmark | ? | 0,5 | ? | 1 |
Sweden | ? | 0,5 | ? | 1,5 (1) |
Remarks | ||||
Sweden | (1) 15 minutes average value |
no data available
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Wear safety goggles or eye protection in combination with breathing protection if powder.
Protective gloves.
Use local exhaust or breathing protection.
no data available
PHYSICAL DESCRIPTION: Colorless needles or purple crystalline solid. Taste threshold concentration: 0.0005 mg/L. Odor threshold concentration (detection): 0.3 mg. (NTP, 1992)
NEEDLES FROM DILUTE ALCOHOL, PETROLEUM ETHER
no data available
9°C(lit.)
250°C(lit.)
Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
no data available
52°C(lit.)
no data available
no data available
no data available
no data available
less than 1 mg/mL at 70° F (NTP, 1992)
log Kow= 3.77
no data available
1.596 g/cm3
(air = 1): 6.8
no data available
Decomposes on heating and on contact with strong oxidants. This produces toxic and corrosive fumes including hydrogen chloride. Decomposes on burning. This produces toxic and corrosive fumes including hydrogen chloride. The substance is a weak acid.
no data available
Non-combustible. /Trichlorophenol/2,3,6-TRICHLOROPHENOL is incompatible with acid chlorides, acid anhydrides and oxidizing agents. (NTP, 1992).
no data available
no data available
When heated to decomp it emits toxic fumes of /hydrogen chloride/.
no data available
no data available
no data available
no data available
no data available
no data available
See Notes.
See Notes.
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed.
Pure cultures of the bacteria KC3 degraded 2,3,6-trichlorophenol under aerobic conditions(1). An actinomycete, Rhodococcus chlorophenolious has been shown to metabolize 2,3,6-trichlorophenol(2). The aerobic biodegradation half-life of 2,3,6-trichlorophenol in a mixed bacterial culture was 25 days, with a lag time of about 23 days(3). 2,3,6-Trichlorophenol (8 uM) was completely degraded in an anaerobic batch reactor over a 6 day incubation period(4).
A BCF value of 400 was calculated for 2,3,6-trichlorophenol(SRC), using a log Kow of 3.77(1) and a recommended regression-derived equation(2). According to a classification scheme(3), this BCF value suggests that bioconcentration in aquatic organisms is high(SRC).
Based on a pKa of 5.8(1), 2,3,6-trichlorophenol is expected to dissociate significantly in moist soil surfaces. Based on a recommended classification scheme(2), a Koc value of 2,700(SRC), determined from a log Kow of 3.77(3) and a recommended regression-derived equation(4), indicates that 2,3,6-trichlorophenol is expected to have slight mobility in soil, but the mobility of the anion is expected to be greater than that of the neutral species(5).
no data available
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
ADR/RID: UN2020 (For reference only, please check.)
IMDG: UN2020 (For reference only, please check.)
IATA: UN2020 (For reference only, please check.)
ADR/RID: CHLOROPHENOLS, SOLID (For reference only, please check.)
IMDG: CHLOROPHENOLS, SOLID (For reference only, please check.)
IATA: CHLOROPHENOLS, SOLID (For reference only, please check.)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
ADR/RID: III (For reference only, please check.)
IMDG: III (For reference only, please check.)
IATA: III (For reference only, please check.)
ADR/RID: No
IMDG: No
IATA: No
no data available
no data available
Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken.No data are available on this isomer but a mixture of trichlorophenols may cause irritation of the skin, eyes and respiratory tract.These substances may cause acute metabolic effects resulting in damage in several organs notably CNS.Some technical products may contain highly toxic impurities including polychlorinated dibenzo-p-dioxins and furans.Depending on the degree of exposure, periodic medical examination is suggested.