Chemical Book India PDF
Chemical Safety Data Sheet MSDS / SDS

2,3,6-trichlorophenol SDS

Revision Date:2024-04-25 Revision Number:1
Section 1 Section 2 Section 3 Section 4 Section 5 Section 6 Section 7 Section 8 Section 9 Section 10 Section 11 Section 12 Section 13 Section 14 Section 15 Section 16

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: 2,3,6-trichlorophenol
  • CAS: 933-75-5

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company:Chemicalbook.in
  • Address:5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
  • Telephone:+91 9550333722

SECTION 2: Hazards identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Skin irritation, Category 2

Eye irritation, Category 2

GHS label elements, including precautionary statements

  • Pictogram(s)
  • Signal word Warning
Hazard statement(s)

H302 Harmful if swallowed

H315 Causes skin irritation

H319 Causes serious eye irritation

Precautionary statement(s)
Prevention

P264 Wash ... thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

Response

P301+P317 IF SWALLOWED: Get medical help.

P330 Rinse mouth.

P302+P352 IF ON SKIN: Wash with plenty of water/...

P321 Specific treatment (see ... on this label).

P332+P317 If skin irritation occurs: Get medical help.

P362+P364 Take off contaminated clothing and wash it before reuse.

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Storage

none

Disposal

P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

SECTION 3: Composition/information on ingredients

Substance

  • Chemical name: 2,3,6-trichlorophenol
  • Common names and synonyms: 2,3,6-trichlorophenol
  • CAS number: 933-75-5
  • EC number: 213-271-7
  • Concentration: 100%

SECTION 4: First aid measures

Description of necessary first-aid measures

If inhaled

Fresh air, rest. Refer for medical attention.

Following skin contact

Remove contaminated clothes. Rinse and then wash skin with water and soap.

Following eye contact

Rinse with plenty of water (remove contact lenses if easily possible).

Following ingestion

Rinse mouth. Refer for medical attention .

Most important symptoms/effects, acute and delayed

SYMPTOMS: Symptoms of exposure to this compound include painless blanching or erythema, vomiting, collapse, coma, profuse sweating, intense thirst, nausea, diarrhea, cyanosis, hyperactivity, stupor, blood pressure fall, hyperpnea, abdominal pain, hemolysis, convulsions and pulmonary edema followed by pneumonia. Other symptoms include irritation of the skin with redness and edema, eye irritation, corneal injury and iritis. The dusts cause irritation of the nose and pharynx. Exposure can cause irritation of the mucous membranes and respiratory tract, severe destruction of tissue (due to intensity and duration of exposure) and burns. Symptoms of exposure to a related compound include softening and whitening of the skin followed by development of painful burns, headache, dizziness, rapid and difficult breathing and weakness. Ingestion of a related compound causes severe burns and internal damage. Chronic exposure causes digestive disturbances, nervous disorders, skin eruptions, dermatitis, liver damage and kidney damage. ACUTE/CHRONIC HAZARDS: This compound may be harmful by inhalation or ingestion. It is an irritant of the skin, eyes, mucous membranes and upper respiratory tract. Prolonged contact may result in severe burns and destruction of tissue. When heated to decomposition it emits toxic fumes of carbon monoxide, carbon dioxide and hydrogen chloride gas. (NTP, 1992)

Indication of immediate medical attention and special treatment needed, if necessary

For advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious or in respiratory arrest. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias if necessary . Start an IV with D5W TKO /SRP: To keep open, "minimal flow rate"/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema . For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors for hypotension with a normal fluid volume. Watch for signs of fluid overload . Administer 1% solution methylene blue if patient is symptomatic with severe hypoxia, cyanosis, and cardiac compromise not responding to oxygen. . Treat seizures with diazepam (Valium). ... Use proparacaine hydrochloride to assist eye irrigation . Phenols and related compounds

SECTION 5: Firefighting measures

Suitable extinguishing media

Extinguish fire using agent suitable for type of surrounding fire. Material itself does not burn or burns with difficulty. Trichlorophenol

Specific hazards arising from the chemical

This chemical is combustible. (NTP, 1992)

Special protective actions for fire-fighters

Use foam, dry powder, carbon dioxide.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

Environmental precautions

Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

Methods and materials for containment and cleaning up

Land Spill: Dig a pit, pond, lagoon, or holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner./ Cover solids with plastic sheet to prevent dissolving in rain or fire fighting water. Trichlorophenol

SECTION 7: Handling and storage

Precautions for safe handling

NO open flames. Above 79°C use a closed system and ventilation. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing. Separated from strong oxidants and food and feedstuffs.

SECTION 8: Exposure controls/personal protection

Control parameters

Occupational Exposure limit values
Component 2,3,6-trichlorophenol
CAS No. 933-75-5
Limit value - Eight hours Limit value - Short term
ppm mg/m3 ppm mg/m3
Denmark ? 0,5 ? 1
Sweden ? 0,5 ? 1,5 (1)
Remarks
Sweden (1) 15 minutes average value
Biological limit values

no data available

Appropriate engineering controls

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Wear safety goggles or eye protection in combination with breathing protection if powder.

Skin protection

Protective gloves.

Respiratory protection

Use local exhaust or breathing protection.

Thermal hazards

no data available

SECTION 9: Physical and chemical properties and safety characteristics

  • Physical state:

    PHYSICAL DESCRIPTION: Colorless needles or purple crystalline solid. Taste threshold concentration: 0.0005 mg/L. Odor threshold concentration (detection): 0.3 mg. (NTP, 1992)

  • Colour:

    NEEDLES FROM DILUTE ALCOHOL, PETROLEUM ETHER

  • Odour:

    no data available

  • Melting point/freezing point:

    9°C(lit.)

  • Boiling point or initial boiling point and boiling range:

    250°C(lit.)

  • Flammability:

    Combustible. Gives off irritating or toxic fumes (or gases) in a fire.

  • Lower and upper explosion limit/flammability limit:

    no data available

  • Flash point:

    52°C(lit.)

  • Auto-ignition temperature:

    no data available

  • Decomposition temperature:

    no data available

  • pH:

    no data available

  • Kinematic viscosity:

    no data available

  • Solubility:

    less than 1 mg/mL at 70° F (NTP, 1992)

  • Partition coefficient n-octanol/water:

    log Kow= 3.77

  • Vapour pressure:

    no data available

  • Density and/or relative density:

    1.596 g/cm3

  • Relative vapour density:

    (air = 1): 6.8

  • Particle characteristics:

    no data available

SECTION 10: Stability and reactivity

Reactivity

Decomposes on heating and on contact with strong oxidants. This produces toxic and corrosive fumes including hydrogen chloride. Decomposes on burning. This produces toxic and corrosive fumes including hydrogen chloride. The substance is a weak acid.

Chemical stability

no data available

Possibility of hazardous reactions

Non-combustible. /Trichlorophenol/2,3,6-TRICHLOROPHENOL is incompatible with acid chlorides, acid anhydrides and oxidizing agents. (NTP, 1992).

Conditions to avoid

no data available

Incompatible materials

no data available

Hazardous decomposition products

When heated to decomp it emits toxic fumes of /hydrogen chloride/.

SECTION 11: Toxicological information

Acute toxicity

  • Oral: no data available
  • Inhalation: no data available
  • Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

no data available

Reproductive toxicity

no data available

STOT-single exposure

See Notes.

STOT-repeated exposure

See Notes.

Aspiration hazard

Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed.

SECTION 12: Ecological information

Toxicity

  • Toxicity to fish: no data available
  • Toxicity to daphnia and other aquatic invertebrates: no data available
  • Toxicity to algae: no data available
  • Toxicity to microorganisms: no data available

Persistence and degradability

Pure cultures of the bacteria KC3 degraded 2,3,6-trichlorophenol under aerobic conditions(1). An actinomycete, Rhodococcus chlorophenolious has been shown to metabolize 2,3,6-trichlorophenol(2). The aerobic biodegradation half-life of 2,3,6-trichlorophenol in a mixed bacterial culture was 25 days, with a lag time of about 23 days(3). 2,3,6-Trichlorophenol (8 uM) was completely degraded in an anaerobic batch reactor over a 6 day incubation period(4).

Bioaccumulative potential

A BCF value of 400 was calculated for 2,3,6-trichlorophenol(SRC), using a log Kow of 3.77(1) and a recommended regression-derived equation(2). According to a classification scheme(3), this BCF value suggests that bioconcentration in aquatic organisms is high(SRC).

Mobility in soil

Based on a pKa of 5.8(1), 2,3,6-trichlorophenol is expected to dissociate significantly in moist soil surfaces. Based on a recommended classification scheme(2), a Koc value of 2,700(SRC), determined from a log Kow of 3.77(3) and a recommended regression-derived equation(4), indicates that 2,3,6-trichlorophenol is expected to have slight mobility in soil, but the mobility of the anion is expected to be greater than that of the neutral species(5).

Other adverse effects

no data available

SECTION 13: Disposal considerations

Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

SECTION 14: Transport information

UN Number

ADR/RID: UN2020 (For reference only, please check.)

IMDG: UN2020 (For reference only, please check.)

IATA: UN2020 (For reference only, please check.)

UN Proper Shipping Name

ADR/RID: CHLOROPHENOLS, SOLID (For reference only, please check.)

IMDG: CHLOROPHENOLS, SOLID (For reference only, please check.)

IATA: CHLOROPHENOLS, SOLID (For reference only, please check.)

Transport hazard class(es)

ADR/RID: 6.1 (For reference only, please check.)

IMDG: 6.1 (For reference only, please check.)

IATA: 6.1 (For reference only, please check.)

Packing group, if applicable

ADR/RID: III (For reference only, please check.)

IMDG: III (For reference only, please check.)

IATA: III (For reference only, please check.)

Environmental hazards

ADR/RID: No

IMDG: No

IATA: No

Special precautions for user

no data available

Transport in bulk according to IMO instruments

no data available

SECTION 15: Regulatory information

Safety, health and environmental regulations specific for the product in question

European Inventory of Existing Commercial Chemical Substances (EINECS)
Listed.
EC Inventory
Listed.
United States Toxic Substances Control Act (TSCA) Inventory
Listed.
China Catalog of Hazardous chemicals 2015
Not Listed.
New Zealand Inventory of Chemicals (NZIoC)
Listed.
(PICCS)
Not Listed.
Vietnam National Chemical Inventory
Listed.
IECSC)
Not Listed.
Korea Existing Chemicals List (KECL)
Not Listed.

SECTION 16: Other information

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%

References

  • IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
  • HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
  • IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
  • CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
  • ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
  • Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
  • ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Other Information

Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken.No data are available on this isomer but a mixture of trichlorophenols may cause irritation of the skin, eyes and respiratory tract.These substances may cause acute metabolic effects resulting in damage in several organs notably CNS.Some technical products may contain highly toxic impurities including polychlorinated dibenzo-p-dioxins and furans.Depending on the degree of exposure, periodic medical examination is suggested.

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any