Acute toxicity - Category 3, Oral
Acute toxicity - Category 2, Dermal
Acute toxicity - Category 3, Inhalation
H301 Toxic if swallowed
H310 Fatal in contact with skin
H331 Toxic if inhaled
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P262 Do not get in eyes, on skin, or on clothing.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P316 Get emergency medical help immediately.
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
no data available
Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
Rinse with pure water for at least 15 minutes. Consult a doctor.
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Extremely toxic by oral, skin, or eye contact. (EPA, 1998)
Rapid support of respiration and circulation is essential to successful treatment of cyanide intoxication. Massive cyanide overdoses have survived with only good supportive care. Immediate attention should be directed toward assisted ventilation, administration of 100% oxygen, insertion of intravenous lines, and institution of cardiac monitoring. Obtain an arterial blood gas immediately and correct any severe metabolic acidosis (pH below 7.15). Oxygen (100%) should be used routinely in moderate or severely symptomatic patients even in the presence of a normal pO2, since 100% O2 increases O2 delivery, may reactivate cyanide-inhibited mitochondrial enzymes, and potentiates the effect of thiosulfate. Avoid mouth to mouth resuscitation during CPR in order to prevent self poisoning. Cyanides
Foam, carbon dioxide, dry chemical. (EPA, 1998)
Cyanide fumes released when heated to decomposition. Avoid alkali, oxidizing material. (EPA, 1998)
Wear self-contained breathing apparatus for firefighting if necessary.
Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.
Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
no data available
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Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
no data available
Straw colored liquid. Used as a solvent /intermediate in production of ethyl lactate and lactic acid. (EPA, 1998)
YELLOW LIQUID
no data available
-40°C
90°C17 mm Hg(lit.)
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64.7°C
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greater than or equal to 100 mg/mL at 73° F (NTP, 1992)
log Kow= -0.94
10 mm Hg at 165.2° F (EPA, 1998)
0.991 g/mL at 20°C(lit.)
2.45 (EPA, 1998) (Relative to Air)
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IT HAS MODERATE FIRE HAZARD WHEN EXPOSED TO HEAT OR FLAME ...LACTONITRILE is incompatible with strong acids, strong bases and strong reducing agents. It is also incompatible with strong oxidizers. In the presence of alkali, it evolves toxic compounds. (NTP, 1992).
no data available
Evolves hydrocyanic acid in presence of alkali.
When heated to decomp, it releases highly toxic cyanide fumes.
no data available
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AEROBIC: The relatively low molecular weight hydrocarbon structure of 2-hydroxypropanenitrile suggests that biodegradation in soil and water is expected to be an important fate process(1). One screening study has demonstrated that 2-hydroxypropanenitrile was readily degraded in Ohio River water in the US(2), although this process could have been hydrolysis. Using Ohio River water as inoculum (with no special acclimation) and an aerobic test system, theoretical BODs of 50% and 70% were measured for 2-hydroxypropanenitrile after 2 and 5 day inoculation periods, respectively, at concns of 0.4-15 mg/l(2); re-dosing the system resulted in a 60% theoretical BOD(2). An activated sludge system that was acclimated to 2-hydroxypropanenitrile experienced a 87-98% BOD removal over a 4 week operation period while receiving influent 2-hydroxypropanenitrile levels that averaged 88 mg/l(3).
An estimated BCF of 3 was calculated for 2-hydroxypropanenitrile(SRC), using a log Kow of -0.94(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low. 2-Hydroxypropanenitrile hydrolyzes in water(4) which suggests that bioconcentration in aquatic organisms should not be environmentally important(SRC).
Using a structure estimation method based on molecular connectivity indices(1), the Koc for 2-hydroxypropanenitrile can be estimated to be about 1(SRC). According to a classification scheme(2), this estimated Koc value suggests that 2-hydroxypropanenitrile is expected to have very high mobility in soil. 2-Hydroxypropanenitrile hydrolyzes in water(3) which suggests that leaching in soil is likely to occur(SRC).
no data available
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
ADR/RID: UN3276 (For reference only, please check.)
IMDG: UN3276 (For reference only, please check.)
IATA: UN3276 (For reference only, please check.)
ADR/RID: NITRILES, LIQUID, TOXIC, N.O.S. (For reference only, please check.)
IMDG: NITRILES, LIQUID, TOXIC, N.O.S. (For reference only, please check.)
IATA: NITRILES, LIQUID, TOXIC, N.O.S. (For reference only, please check.)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
ADR/RID: No
IMDG: No
IATA: No
no data available
no data available