Acute toxicity - Category 4, Oral
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2
H302 Harmful if swallowed
H411 Toxic to aquatic life with long lasting effects
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P391 Collect spillage.
none
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
no data available
Fresh air, rest. Refer for medical attention. See Notes.
Rinse skin with plenty of water or shower.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rest. Refer for medical attention . See Notes.
Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]: TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. (ERG, 2016)
IN ALL CASES CONSULT A DOCTOR. INHALATION: Symptoms: Blue skin. Blue lips or finger nails. Dizziness. Headache. Nausea. Shortness of breath. Confusion. Convulsions. Unconsciousness. Symptoms may be delayed. First aid: Fresh air, rest. Refer for medical attention. SKIN: Symptoms: Redness. First aid: Remove contaminated clothes. Rinse skin with plenty of water or shower. EYES: Symptoms: Redness. Pain. First aid: First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. INGESTION: Symptoms: Blue skin. Blue lips or finger nails. Dizziness. Headache. Nausea. Shortness of breath. Confusion. Convulsions. Unconsciousness. Symptoms may be delayed. First aid: Rest. Refer for medical attention.
Powder, alcohol-resistant foam, water spray, carbon dioxide.
Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]: Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form. (ERG, 2016)
Use water spray, powder, alcohol-resistant foam, carbon dioxide.
Personal protection: P2 filter respirator for harmful particles. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Personal protection: P2 filter respirator for harmful particles. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. (Extra personal protection: P2 filter respirator for harmful particles). Do NOT let this chemical enter the environment.
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Separated from food and feedstuffs.
no data available
no data available
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Wear safety spectacles.
Protective gloves.
Use local exhaust or breathing protection.
no data available
Solid. Crystalline.
Yellow.
no data available
>= 108 - <= 112 °C. Atm. press.:101.3 kPa.
>= 297.62 - <= 320 °C. Atm. press.:101.3 kPa.
Combustible.
no data available
205 °C. Atm. press.:101.3 kPa.
522°C
no data available
no data available
no data available
Very soluble in ether, ethanol, acetic acid
log Pow = >= 2.14 - <= 2.17. Temperature:25 °C.
0 mm Hg. Temperature:25 °C. Remarks:US EPA; Estimation Program Interface (EPI) Suite. Ver.3.12. Nov 30, 2004. Available from, as of Oct 10, 2007:, HSDB Database.;>= 0.001 - <= 0.007 Torr. Temperature:> 62.53 °C. Remarks:Journal of Chemical Thermodynamics; vol. 35; nb. 8; (2003); p. 1343 – 1359 (REAXYS Database).
<= 1 g/cm3. Temperature:20 °C.
no data available
no data available
Decomposes on burning. This produces toxic and corrosive gases including nitrogen oxides.
no data available
2-CHLORO-4-NITROANILINE can react with oxidizing materials. (NTP, 1992)
no data available
The substance decomposes on burning producing toxic and corrosive gases, including nitrogen oxides.
no data available
no data available
no data available
no data available
no data available
no data available
no data available
The substance is mildly irritating to the skin. The substance may cause effects on the blood. This may result in the formation of methaemoglobin. Medical observation is indicated. The effects may be delayed.
no data available
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20°C.
AEROBIC: The biodegradability of 2-chloro-4-nitroaniline was measured using both the semistatic OECD test and the dynamic system, Pitter test. 2-Chloro-4-nitroaniline is considered non-biodegradable (half-life of much greater than 4 weeks) using both non-adapted and adapted inoculum for both tests(1). Using a modification of the Pitter test where the first step is an acclimation of a mixed microbial population to 2-chloro-4-nitroaniline (at 25 mg/L) in a semi-continuous activated sludge system followed by a die-away test in closed flasks, only a slight amount of degradation occurred. The initial inoculum was a 1:1 mixture of activated sludge from a domestic sewage plant and a solution containing organic material extracted from river mud. In the semi-continuous activated sludge system, 80% of the added 2-chloro-4-nitroaniline was still present after 17 days using both the mixed inoculum and an activated sewage sludge(2). 2-Chloro-4-nitroaniline is regarded as non-biodegradable in the aquatic environment as well as in communal and industrial sewage treatment plants(2).
An estimated BCF of 9 was calculated in fish for 2-chloro-4-nitroaniline(SRC), using a log Kow of 2.14(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
The Koc of 2-chloro-4-nitroaniline is estimated as 350(SRC), using a log Kow of 2.14(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that 2-chloro-4-nitroaniline is expected to moderate mobility in soil. However, anilines are expected to bind strongly to humus or organic matter in soils due to the high reactivity of the aromatic amino group(4,5), suggesting that mobility may be much lower in some soils(SRC). The log Koc of 2-chloro-4-nitroaniline was measured as 2.36 in Yangtze river sediment (37.1% sand, 49.3% silt, 13.6% clay, 1.28% organic carbon, pH 7.44)(1). The log Koc was also measured as 3.63 in modified clay(6). These values correspond to Koc values of 230 and 4300, respectively(SRC).
no data available
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
ADR/RID: UN2237 (For reference only, please check.)
IMDG: UN2237 (For reference only, please check.)
IATA: UN2237 (For reference only, please check.)
ADR/RID: CHLORONITROANILINES (For reference only, please check.)
IMDG: CHLORONITROANILINES (For reference only, please check.)
IATA: CHLORONITROANILINES (For reference only, please check.)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
ADR/RID: III (For reference only, please check.)
IMDG: III (For reference only, please check.)
IATA: III (For reference only, please check.)
ADR/RID: Yes
IMDG: Yes
IATA: Yes
no data available
no data available
Depending on the degree of exposure, periodic medical examination is indicated.Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.