Butanone SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Butanone
- CAS： 78-93-3
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Flammable liquids, Category 2
Eye irritation, Category 2
Specific target organ toxicity – single exposure, Category 3
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Danger
H225 Highly flammable liquid and vapour
H319 Causes serious eye irritation
H336 May cause drowsiness or dizziness
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment.
P242 Use non-sparking tools.
P243 Take action to prevent static discharges.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P264 Wash ... thoroughly after handling.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse affected areas with water [or shower].
P370+P378 In case of fire: Use ... to extinguish.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
P403+P235 Store in a well-ventilated place. Keep cool.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Butanone
- Common names and synonyms: Butanone
- CAS number: 78-93-3
- EC number: 201-159-0
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse skin with plenty of water or shower.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention .
Most important symptoms/effects, acute and delayed
Liquid causes eye burn. Vapor irritates eyes, nose, and throat; can cause headache, dizziness, nausea, weakness, and loss of consciousness. (USCG, 1999)
Indication of immediate medical attention and special treatment needed, if necessary
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Ketones and related compounds
SECTION 5: Firefighting measures
Suitable extinguishing media
In case of fire: keep drums, etc., cool by spraying with water. Powder, AFFF, foam, carbon dioxide.
Specific hazards arising from the chemical
Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water. (ERG, 2016)
Special protective actions for fire-fighters
Use alcohol-resistant foam, water, powder, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: self-contained breathing apparatus. Do NOT wash away into sewer. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: self-contained breathing apparatus. Do NOT wash away into sewer. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Evacuate and restrict persons not wearing protective equipment from area of spill or leak until cleanup is complete. Remove all ignition sources. Establish forced ventilation to keep levels below explosive limit. Absorb liquids in vermiculite, dry sand, earth, peat, carbon, or similar material and deposit in sealed containers. Oil-skimming equipment and sorbent foams can be applied to slick if done immediately. Keep this chemical out of a confined space ... because of the possibility of an explosion ... It may be necessary to contain and dispose of this chemical as a hazardous waste. If material or contaminated runoff enters waterways, notify downstream users of potentially contaminated waters. Contact your Department of Environmental Protection or your regional office of the federal EPA for specific recommendations. If employees are required to clean up spills, they must be properly trained and equipped. OSHA 1910.120(q) may be applicable.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames, NO sparks and NO smoking. Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling. Use non-sparking handtools. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Fireproof. Separated from strong oxidants and strong acids. Cool. Well closed.Methyl ethyl ketone must be stored to avoid contact with strong oxidizers (such as chlorine, bromine, and fluorine) since violent reactions may occur. Store in tightly closed containers in a cool, well ventilated area away from sources of heat, sparks, or flame. Sources of ignition such as smoking and open flames are prohibited where methyl ethyl ketone is handled, used or stored in a manner that could create a potential fire or explosion hazard. Metal containers involving the transfer of 5 gallons or more of diethyl ketone should be grounded and bonded. Drums must be equipped with self-closing valves, pressure vacuum bungs, and flame arresters. Use only non-sparking tools and equipment, especially when opening and closing containers of methyl ethyl ketone.
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 200 ppm as TWA; 300 ppm as STEL; BEI issued.MAK: 600 mg/m3, 200 ppm; peak limitation category: I(1); skin absorption (H); pregnancy risk group: C.EU-OEL: 600 mg/m3, 200 ppm as TWA; 900 mg/m3, 300 ppm as STEL
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety goggles.
Protective gloves. Protective clothing.
Use ventilation, local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Methyl ethyl ketone is a colorless fairly volatile liquid with a pleasant pungent odor. Flash point 20°F. Vapors heavier than air. Does not react with water or many common materials. Stable in normal transportation. Irritates the nose, eyes, and throat. Combustion may produce toxic materials. Density 6.7 lb / gal. Used as a solvent, for making other chemicals, and for production of wax from petroleum.
-
Colour：
Colorless liquid
-
Odour：
Acetone-like odor
-
Melting point/freezing point：
-87 °C
-
Boiling point or initial boiling point and boiling range：
80°C(lit.)
-
Flammability：
Class IB Flammable Liquid: Fl.P. below 73°F and BP at or above 100°F.
-
Lower and upper explosion limit/flammability limit：
Lower flammable limit: 1.4% by volume @ 200 deg F (93 deg C); Upper flammable limit: 11.4% by volume @ 200 deg F (93 deg C)
-
Flash point：
-3°C
-
Auto-ignition temperature：
960°F
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
0.40 cP at 25 deg C
-
Solubility：
greater than or equal to 100 mg/mL at 66° F (NTP, 1992)
-
Partition coefficient n-octanol/water：
log Kow = 0.29
-
Vapour pressure：
71 mm Hg ( 20 °C)
-
Density and/or relative density：
0.805g/mLat 25°C(lit.)
-
Relative vapour density：
2.49 (vs air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Reacts violently with strong oxidants and inorganic acids. This generates fire and explosion hazard. Attacks some plastics.
Chemical stability
Stability during transport: stable
Possibility of hazardous reactions
Highly flammable liquid.The vapour is heavier than air and may travel along the ground; distant ignition possible.METHYL ETHYL KETONE is explosive in the form of vapor when exposed to heat, flame or sparks. Ignition on contact with potassium tert-butoxide. Reactive with strong oxidizing materials, and will dissolve or soften some plastics. Mixture with 2-propanol will form explosive peroxides during storage. Vigorous reaction with chloroform in the presence of alkali (sodium hydroxide, potassium hydroxide), chlorosulfonic acid, fuming sulfuric acid (oleum) [Lewis, 3rd ed., 1993, p. 855]. Reaction with hydrogen peroxide in the presence of nitric acid forms heat- and shock-sensitive explosive acetone peroxides. [Bjorklund, G. H. et al., Trans. R. Soc. Can, 1950, 44, p. 25].
Conditions to avoid
no data available
Incompatible materials
Reacts violently with strong oxidants and inorganic acids causing fire and explosion hazard. Attacks some plastic.
Hazardous decomposition products
MEK in air is rapidly decomposed by photochemical processes, mainly through oxidation by hydroxyl free radicals as well as some decomposition by direct photolysis ... /with a/ half-life of 5.4 hr for photochemical decomposition in urban atmospheres.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 3400 mg/kg bw
- Inhalation: LC50 Rat inhalation >5000 ppm/6 hr
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Cancer Classification: Group D Not Classifiable as to Human Carcinogenicity
Reproductive toxicity
No information on the reproductive or developmental effects of methyl ethyl ketone in humans was located. An inhalation study in mice exposed to methyl ethyl ketone reported decreased fetal weight and fetal malformations. Developmental effects have also been reported in rats following oral and inhalation exposures.
STOT-single exposure
The substance is irritating to the eyes and respiratory tract. The substance may cause effects on the central nervous system. Exposure could cause unconsciousness. If swallowed the substance easily enters the airways and could result in aspiration pneumonitis.
STOT-repeated exposure
The substance defats the skin, which may cause dryness or cracking. Animal tests show that this substance possibly causes toxicity to human reproduction or development.
Aspiration hazard
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50; Species: Lepomis macrochirus (bluegill); Concentration: 5,640-1,690 mg/L for 24 to 96 hr /Conditions of bioassay not specified
- Toxicity to daphnia and other aquatic invertebrates: LC50; Species: Daphnia magna (water flea); Concentration: <520 mg/L for 48 hr /From table; pH 8 and hardness 173; temp not specified
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: Methyl ethyl ketone (MEK) is readily oxidized by microorganisms in activated sludge following selection and/or adaptation, with over 80% being removed in 24 hr. Metabolism in unacclimated sludges is slow.
Bioaccumulative potential
An estimated BCF of 3 was calculated in fish for methyl ethyl ketone(SRC), using a log Kow of 0.29(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
Measured Koc values of 29 and 34 were obtained for methyl ethyl ketone in a silt loam and sandy loam soil respectively(1). A measured Koc value of 3.55 has also been reported(2). According to a classification scheme(3), these Koc values suggest that methyl ethyl ketone is expected to have very high mobility in soil(SRC).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN1193 (For reference only, please check.)
IMDG: UN1193 (For reference only, please check.)
IATA: UN1193 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: ETHYL METHYL KETONE (METHYL ETHYL KETONE) (For reference only, please check.)
IMDG: ETHYL METHYL KETONE (METHYL ETHYL KETONE) (For reference only, please check.)
IATA: ETHYL METHYL KETONE (METHYL ETHYL KETONE) (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 3 (For reference only, please check.)
IMDG: 3 (For reference only, please check.)
IATA: 3 (For reference only, please check.)
Packing group, if applicable
ADR/RID: II (For reference only, please check.)
IMDG: II (For reference only, please check.)
IATA: II (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
The odour warning when the exposure limit value is exceeded is insufficient.