Butan-2-ol SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Butan-2-ol
- CAS： 78-92-2
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Flammable liquids, Category 3
Eye irritation, Category 2
Specific target organ toxicity – single exposure, Category 3
Specific target organ toxicity – single exposure, Category 3
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Warning
H226 Flammable liquid and vapour
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H336 May cause drowsiness or dizziness
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment.
P242 Use non-sparking tools.
P243 Take action to prevent static discharges.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P264 Wash ... thoroughly after handling.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse affected areas with water [or shower].
P370+P378 In case of fire: Use ... to extinguish.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
P403+P235 Store in a well-ventilated place. Keep cool.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Butan-2-ol
- Common names and synonyms: Butan-2-ol
- CAS number: 78-92-2
- EC number: 201-158-5
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse skin with plenty of water or shower.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Give one or two glasses of water to drink. Do NOT induce vomiting. Refer for medical attention .
Most important symptoms/effects, acute and delayed
Exposure Routes: inhalation, ingestion, skin and/or eye contact Symptoms: Irritation eyes, skin, nose, throat; narcosis Target Organs: Eyes, skin, respiratory system, central nervous system (NIOSH, 2016)
Indication of immediate medical attention and special treatment needed, if necessary
Basic Treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for shock and treat if necessary . Monitor for pulmonary edema and treat if necessary . Anticipate seizures and treat if necessary . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal . Higher alcohols (>3 carbons) and related compounds
SECTION 5: Firefighting measures
Suitable extinguishing media
Water spray, alcohol foam, carbon dioxide, dry chemical
Specific hazards arising from the chemical
Excerpt from ERG Guide 129 [Flammable Liquids (Water-Miscible / Noxious)]: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water. (ERG, 2016)
Special protective actions for fire-fighters
Use water spray, powder, foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Wash away remainder with plenty of water.
Environmental precautions
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Wash away remainder with plenty of water.
Methods and materials for containment and cleaning up
1. remove all ignition sources. 2. ventilate area of spill or leak. 3. for small quantities absorb on paper towels. evaporate in safe place (such as fume hood). allow sufficient time for evaporating vapors to ... clear hood ductwork. burn paper in suitable location away from combustible materials. large quantities can be collected and atomized in a suitable combustion chamber.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames, NO sparks and NO smoking. Above 24°C use a closed system, ventilation and explosion-proof electrical equipment. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Fireproof. Separated from strong oxidants and aluminium.... STORE IN PLACES THAT ARE COOL ... PROVIDE ADEQUATE VENTILATION ... LOCATE ... STORAGE AREA WELL AWAY FROM AREAS OF FIRE HAZARD ... KEEP ... FROM POWERFUL OXIDIZING AGENTS ... EXPLOSIVES, OR MATERIALS WHICH REACT WITH AIR OR MOISTURE TO EVOLVE HEAT.
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 100 ppm as TWA
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety goggles.
Protective gloves.
Use ventilation, local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Liquid.
-
Colour：
Colourless.
-
Odour：
HAS A STRONG VINOUS ODOR
-
Melting point/freezing point：
-114.7 °C. Atm. press.:1 atm.
-
Boiling point or initial boiling point and boiling range：
99.5 °C. Atm. press.:1 013 hPa.
-
Flammability：
Class IC Flammable Liquid: Fl.P. at or above 73°F and below 100°F.
-
Lower and upper explosion limit/flammability limit：
Lower flammable limit: 1.7% by volume at 212 deg F (100 deg C); Upper flammable limit: 9.8% by volume at 212 deg F (100 deg C)
-
Flash point：
31 °C. Atm. press.:Ca. 1 atm.
-
Auto-ignition temperature：
405 °C. Atm. press.:1 atm. Remarks:Literature data.
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
dynamic viscosity (in mPa s) = 3.084. Temperature:25.0°C. Remarks:Reported as 3.084 x 10 E-3 Pa s at 25°C.
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Solubility：
Miscible with water
-
Partition coefficient n-octanol/water：
log Pow = 0.65. Temperature:25 °C.
-
Vapour pressure：
23.2 hPa. Temperature:25 °C. Remarks:2.32 kPa at 25°C.
-
Density and/or relative density：
0.81 g/L. Temperature:20 °C.
-
Relative vapour density：
2.6 (vs air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
The substance can form explosive peroxides. Reacts with aluminium when heated to 100°C and strong oxidants such as chromium trioxide. This produces flammable/explosive gas (hydrogen - see ICSC 0001). Attacks some forms of plastic, rubber and coatings.
Chemical stability
Feasible auto oxidation by atmospheric oxygen to form peroxides & peroxy cmpd
Possibility of hazardous reactions
DANGEROUS FIRE HAZARD WHEN EXPOSED TO HEAT OR FLAME.Attacks plastics. [Handling Chemicals Safely 1980. p. 236]. Acetyl bromide reacts violently with alcohols or water (Merck 11th ed. 1989). Mixtures of alcohols with concentrated sulfuric acid and strong hydrogen peroxide can cause explosions. Example: An explosion will occur if dimethylbenzylcarbinol is added to 90% hydrogen peroxide then acidified with concentrated sulfuric acid. Mixtures of ethyl alcohol with concentrated hydrogen peroxide form powerful explosives. Mixtures of hydrogen peroxide and 1-phenyl-2-methyl propyl alcohol tend to explode if acidified with 70% sulfuric acid [Chem. Eng. News 45(43):73 1967; J, Org. Chem. 28:1893 1963]. Alkyl hypochlorites are violently explosive. They are readily obtained by reacting hypochlorous acid and alcohols either in aqueous solution or mixed aqueous-carbon tetrachloride solutions. Chlorine plus alcohols would similarly yield alkyl hypochlorites. They decompose in the cold and explode on exposure to sunlight or heat. Tertiary hypochlorites are less unstable than secondary or primary hypochlorites [NFPA 491 M 1991]. Base-catalysed reactions of isocyanates with alcohols should be carried out in inert solvents. Such reactions in the absence of solvents often occur with explosive violence [Wischmeyer 1969].
Conditions to avoid
no data available
Incompatible materials
Contact with strong oxidizers may cause fires and ... explosions.
Hazardous decomposition products
When heated to decomposition it emits acrid smoke & fumes.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 - rat (male) - 2 054 mg/kg bw. Remarks:95% fiducial limits were 1283 - 4018 mg/kg bw.
- Inhalation: Mortality in 14 days following exposure - rat (male) - 16 000 ppm.
- Dermal: LD50 - rat (male/female) - > 2 000 mg/kg bw.
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes and upper respiratory tract. Exposure far above the OEL could cause lowering of consciousness. If swallowed the substance may cause vomiting and could result in aspiration pneumonitis.
STOT-repeated exposure
The substance defats the skin, which may cause dryness or cracking.
Aspiration hazard
A harmful contamination of the air will be reached slowly on evaporation of this substance at 20°C.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 - Pimephales promelas - 2 993 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - 308 mg/L - 48 h.
- Toxicity to algae: EC50 - Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum) - 1 972 mg/L - 72 h.
- Toxicity to microorganisms: Toxicity threshold - Pseudomonas putida - 500 mg/L - 16 h.
Persistence and degradability
Adapted activated sludge /bench scale activated sludges fill and draw operations/: Product as sole carbon source- 98.5%, removal at 55.0 mg COD (chemical oxygen demand)/g dry inoculum/hr
Bioaccumulative potential
An estimated BCF of 3 was calculated for sec-butyl alcohol(SRC), using a log Kow of 0.61(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
The Koc of sec-butyl alcohol is estimated as 50(SRC), using a log Kow of 0.61(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that sec-butyl alcohol is expected to have high mobility in soil(SRC).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN1120 (For reference only, please check.)
IMDG: UN1120 (For reference only, please check.)
IATA: UN1120 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: BUTANOLS (For reference only, please check.)
IMDG: BUTANOLS (For reference only, please check.)
IATA: BUTANOLS (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 3 (For reference only, please check.)
IMDG: 3 (For reference only, please check.)
IATA: 3 (For reference only, please check.)
Packing group, if applicable
ADR/RID: II (For reference only, please check.)
IMDG: II (For reference only, please check.)
IATA: II (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Check for peroxides prior to distillation; eliminate if found.