1,1,2-trichloroethane SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： 1,1,2-trichloroethane
- CAS： 79-00-5
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 4, Oral
Acute toxicity - Category 4, Dermal
Acute toxicity - Category 4, Inhalation
Carcinogenicity, Category 2
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Warning
H302 Harmful if swallowed
H312 Harmful in contact with skin
H332 Harmful if inhaled
H351 Suspected of causing cancer
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P203 Obtain, read and follow all safety instructions before use.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P317 Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P318 IF exposed or concerned, get medical advice.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: 1,1,2-trichloroethane
- Common names and synonyms: 1,1,2-trichloroethane
- CAS number: 79-00-5
- EC number: 201-166-9
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
Rinse with plenty of water (remove contact lenses if easily possible). Refer for medical attention.
Rinse mouth. Refer for medical attention . Do NOT induce vomiting.
Most important symptoms/effects, acute and delayed
Inhalation causes irritation of the nose, throat, and lungs. High concentrations may cause death by respiratory failure. Highly toxic by ingestion; may cause liver or kidney damage or myocardial irritability. Causes severe irritation of the gastrointestinal tract. Vapor may produce superficial skin burns or defatting type dermatitis and may irritate the eyes. (USCG, 1999)
Indication of immediate medical attention and special treatment needed, if necessary
Trichloroethane is less toxic than trichloroethylene at a given concentration, but treatment is similar with initial attention directed toward support of ventilation, correction of hypotension, and cardiac monitoring as indicated. Recovery after termination of exposure usually is rapid, with recovery from light anesthesia occuring within 5 minutes. Trichloroethane
SECTION 5: Firefighting measures
Suitable extinguishing media
Wear special protective clothing and positive pressure self-contained breathing apparatus.
Specific hazards arising from the chemical
Special Hazards of Combustion Products: Toxic gases including hydrogen chloride and very small amounts of phosgene and chlorine are produced. Behavior in Fire: Forms a flammable vapor-air mixture at 109°F and higher. (USCG, 1999)
Special protective actions for fire-fighters
Use powder, water spray, foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
1) remove all ignition sources. 2) ventilate area of spill or leak. 3) collect for reclamation or absorb in vermiculite, dry sand, or similar material.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames. NO contact with hot surfaces. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Separated from strong oxidants, strong bases and metals. Well closed. Ventilation along the floor. Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access.Store in a cool, dry, well-ventilated location. Separate from oxidizing materials, aluminum, ammonia.
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 10 ppm as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans).MAK: 55 mg/m3, 10 ppm; peak limitation category: II(2); skin absorption (H); carcinogen category: 3B
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety spectacles or face shield.
Protective gloves. Protective clothing.
Use ventilation, local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Liquid. Liquid.
-
Colour：
Colourless.
-
Odour：
Pleasant odor
-
Melting point/freezing point：
-36 °C. Atm. press.:Ca. 1 atm.
-
Boiling point or initial boiling point and boiling range：
114 °C. Atm. press.:1 013 hPa.
-
Flammability：
Combustible Liquid, forms dense soot.
-
Lower and upper explosion limit/flammability limit：
Lower limit: 6%; upper limit: 15.5%
-
Flash point：
> 75 °C.
-
Auto-ignition temperature：
460 °C. Atm. press.:Ca. 1 013 hPa.
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
dynamic viscosity (in mPa s) = 1.2. Temperature:20°C.
-
Solubility：
1 to 5 mg/mL at 68° F (NTP, 1992)
-
Partition coefficient n-octanol/water：
log Pow = > 2.05 - < 2.49. Temperature:20 °C.
-
Vapour pressure：
100 hPa. Temperature:50 °C.
-
Density and/or relative density：
1.44. Temperature:20 °C.
-
Relative vapour density：
4.63 (NTP, 1992) (Relative to Air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
100 ppm; NIOSH considers 1,1,2-trichloroethane to be a potential occupational carcinogen.
Decomposes on contact with hot surfaces or flames. This produces toxic and corrosive gases including hydrogen chloride (see ICSC 0163) and phosgene (see ICSC 0007). Reacts with strong bases, strong oxidants and metals. This generates fire and explosion hazard.
Chemical stability
Stable in air at ordinary temp; in absence of air or water it is stable to approx 110 deg c
Possibility of hazardous reactions
Nonflammable /liquid/The vapour is heavier than air.1,1,2-TRICHLOROETHANE is sensitive to light and heat. Incompatible with strong oxidizing agents and strong bases. Reacts violently with sodium, potassium, magnesium, and aluminum. Attacks some plastics, rubber and coatings. (NTP, 1992)
Conditions to avoid
no data available
Incompatible materials
Although apparently stable on contact, mixtures of potassium (or its alloys) with wide range of halocarbons are shock-sensitive and may explode with great violence on light impact. ... Trichloroethane ... /was/ among those investigated.
Hazardous decomposition products
When heated to decomposition it emits toxic fumes of /hydrogen chloride/.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 837 mg/kg
- Inhalation: LC50 - rat (male) - 9 000 mg/m3 air.
- Dermal: LD50 - rabbit (male) - ca. 5 380 mg/kg bw.
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Evaluation: No epidemiological data relevant to the carcinogenicity of 1,1,2-trichloroethane were available. There is limited evidence in experimental animals for the carcinogenicity of 1,1,2-trichloroethane. Overall evaluation: 1,1,2-Trichloroethane is not classifiable as to its carcinogenicity in humans (Group 3).
Reproductive toxicity
No information is available regarding developmental or reproductive effects of 1,1,2-trichloroethane in humans from inhalation or oral exposure. Animal studies have not reported developmental or reproductive effects from oral exposure to 1,1,2-trichloroethane.
STOT-single exposure
The substance is irritating to the eyes and respiratory tract. The substance is mildly irritating to the skin. The substance may cause effects on the central nervous system. This may result in lowering of consciousness. The substance may cause effects on the kidneys and liver. This may result in impaired functions. If swallowed the substance may cause vomiting and could result in aspiration pneumonitis.
STOT-repeated exposure
The substance defats the skin, which may cause dryness or cracking. Repeated or prolonged contact with skin may cause dryness and cracking.
Aspiration hazard
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 - Pleuronectes platessa - 34 mg/L - 48 h.
- Toxicity to daphnia and other aquatic invertebrates: LC50 - Daphnia magna - 18 mg/L - 48 h.
- Toxicity to algae: EC50 - Chlamydomonas reinhardtii - 57 mg/L - 72 h.
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: 1,1,2-Trichloroethane showed no biodegradation in both a 24-day modified shake flask test and a river die-away test(2). Similar results were obtained in another screening biodegradability test(4). When a solution containing 1,1,2-trichloroethane was applied to a column filled with sandy soil, no loss could be attributed to biodegradation(3). One investigation reported very slow biodegradation with long acclimation times for 1,1,2-trichloroethane (1). Vinyl chloride was observed to be a biodegradation product of 1,1,2-trichloroethane when microbes from an anaerobic digester at a municipal wastewater treatment facility were used as inocula(5). No significant degradation occurred over a 16 week incubation period in either sterilized or non-sterile subsurface (5 m deep) soil samples(6). 1,1,2-Trichloroethane has been shown to undergo biotransformation under methanogenic conditions(7). 1,1,2-Trichloroethane at 100 mg/L achieved 5% of its theoretical BOD using an activated sludge inoculum at 30 mg/L over a 4 week incubation period in the Japanese MITI test(8). The anaerobic biodegradation rate constant for 1,1,2-trichloroethane was reported to range from 0.00048 to 0.00096 days-1(9), corresponding to half-lives of 722-1444 days(SRC). The aerobic biodegradation half-life for 1,1,2-trichloroethane was reported to range from 6 months to 1 year(9). The half-life of 1,1,2-trichloroethane in an unpolluted anaerobic aquifer was reported as 6 days (1% organic carbon content), 26 days (0.1% organic carbon content), 335 days (0.01% organic carbon content) and 16 years (0.001% organic carbon content)(10).
Bioaccumulative potential
BCF values of 0.7 to 2.6 were measured in carp exposed to 0.3 mg/L of 1,1,2-trichloroethane during a 6 week incubation period and BCF values of 2.7 to 6.7 were measured in carp exposed to 0.03 mg/L of 1,1,2-trichloroethane during a 6 week incubation period(1). According to a classification scheme(2), these BCF values suggest that bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
The mean Koc of 1,1,2-trichloroethane in a silty clay soil and sandy loam soil ranged from 83-111 and 174-209, respectively(1). According to a classification scheme(2), this range of Koc values suggests that 1,1,2-trichloroethane is expected to have high to moderate mobility in soil(SRC).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN2810 (For reference only, please check.)
IMDG: UN2810 (For reference only, please check.)
IATA: UN2810 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: TOXIC LIQUID, ORGANIC, N.O.S. (For reference only, please check.)
IMDG: TOXIC LIQUID, ORGANIC, N.O.S. (For reference only, please check.)
IATA: TOXIC LIQUID, ORGANIC, N.O.S. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Combustible vapour/air mixtures difficult to ignite, may be developed under certain conditions.Use of alcoholic beverages enhances the harmful effect.The relation between odour and the occupational exposure limit cannot be indicated.Do NOT use in the vicinity of a fire or a hot surface, or during welding.