Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity – single exposure, Category 3
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
no data available
Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention. See Notes.
Rinse and then wash skin with water and soap.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth.
Exposure Routes: inhalation, ingestion, skin and/or eye contact Symptoms: Irritation eyes, skin; central nervous system depression; pulmonary edema; drowsiness; dyspnea (breathing difficulty) Target Organs: Eyes, skin, respiratory system, central nervous system (NIOSH, 2016)
Victims of freon inhalation require management for hypoxic, CNS anesthetic, & cardiac symptoms. Patients must be removed from the exposure environment, & high flow supplemental oxygen should be utilized. The respiratory system should be evaluated for injury, aspiration, or pulmonary edema & treated appropriately. CNS findings should be treated supportively. A calm environment with no physical exertion is imperative to avoid increasing endogenous adrenegic levels. Exogenous adrenergic drugs must not be used to avoid inducing sensitized myocardial dysrhythmias. Atropine is ineffective in treating bradyarrhythmias. For ventricular dysrhythmias, diphenylhydantoin & countershock may be effective. Cryogenic dermal injuries should be treated by water bath rewarming at 40-42 deg C until vasodilatory flush has returned. Elevation of the limb & standard frostbite management with late surgical debridement should be utilized. Ocular exposure requires irrigation & slit lamp evaluation for injury. Freons
In case of fire in the surroundings, use appropriate extinguishing media.
Excerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]: Some may burn but none ignite readily. Containers may explode when heated. Ruptured cylinders may rocket. (ERG, 2016)
In case of fire in the surroundings, use appropriate extinguishing media.
Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment.
Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment.
Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do not let this chemical enter the environment.
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
See Chemical Dangers. Well closed.Well closed.
TLV: 100 ppm as TWA.MAK: 1700 mg/m3, 200 ppm; peak limitation category: II(2); pregnancy risk group: D
no data available
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Wear safety spectacles.
Protective gloves.
Use ventilation, local exhaust or breathing protection.
no data available
1,1,1,2-tetrachloro-2,2-difluoroethane is a colorless solid with a slight, ether-like odor. mp: 40.6°C; bp: 91.5°C.
Colorless liquid or solid
Slight ether odor
39-44°C
93.3°C at 760 mmHg
Noncombustible Solid
no data available
11.8°C
no data available
no data available
no data available
2.1583X10-3 Pa.s at 313.75 K
0.01 % (NIOSH, 2016)
log Kow = 3.41 (est)
40 mm Hg (NIOSH, 2016)
1.726 g/cm3
7.0 (Air = 1)
no data available
Decomposes on contact with hot surfaces or flames. This produces toxic fumes including hydrogen chloride, hydrogen fluoride and phosgene. Reacts with alkali metals, powdered aluminium, magnesium and zinc. Attacks plastics, rubber and coatings.
no data available
1,1,1,2-tetrachloro-2,2-Difluoroethane is non-flammable. Incompatible with active metals such as potassium, sodium, beryllium, powdered aluminum, zinc, magnesium, and calcium. Reacts with acids.
no data available
Chemically-active metals such as potassium, beryllium, powdered aluminum, zinc, magnesium, calcium and sodium; acids.
Decomposes on contact with hot surfaces or flames. This produces toxic fumes including hydrogen chloride, hydrogen fluoride and phosgene.
no data available
no data available
no data available
no data available
no data available
no data available
Inhalation of high levels may cause lung oedema. See Notes. The substance may cause effects on the cardiovascular system and central nervous system. This may result in cardiac disorders and central nervous system depression. Exposure could cause lowering of consciousness.
no data available
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster.
ANAEROBIC: Structurally similar compounds such as Freon 12 and Freon 114 have been shown to biodegrade under anaerobic conditions(1), suggesting that 1,1,1,2-tetrachloro-2,2-difluoroethane may also biodegrade under anaerobic conditions(SRC).
An estimated BCF of 82 was calculated in fish for 1,1,1,2-tetrachloro-2,2,-difluoroethane(SRC), using an estimated log Kow of 3.41(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is moderate(SRC), provided the compound is not metabolized by the organism(SRC).
Using a structure estimation method based on molecular connectivity indices(1), the Koc for 1,1,1,2-tetrachloro-2,2,-difluoroethane can be estimated to be 200(SRC). According to a classification scheme(2), this estimated Koc value suggests that 1,1,1,2-tetrachloro-2,2,-difluoroethane is expected to have moderate mobility in soil.
no data available
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
ADR/RID: no data available
IMDG: no data available
IATA: no data available
ADR/RID: no data available
IMDG: no data available
IATA: no data available
ADR/RID: no data available
IMDG: no data available
IATA: no data available
ADR/RID: no data available
IMDG: no data available
IATA: no data available
ADR/RID: No
IMDG: No
IATA: No
no data available
no data available
Do NOT use in the vicinity of a fire or a hot surface, or during welding.The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort.Rest and medical observation is therefore essential.