1-phenoxypropan-2-ol SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： 1-phenoxypropan-2-ol
- CAS： 770-35-4
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Eye irritation, Category 2
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Warning
H319 Causes serious eye irritation
P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
none
none
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: 1-phenoxypropan-2-ol
- Common names and synonyms: 1-phenoxypropan-2-ol
- CAS number: 770-35-4
- EC number: 212-222-7
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
Rinse with pure water for at least 15 minutes. Consult a doctor.
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Most important symptoms/effects, acute and delayed
no data available
Indication of immediate medical attention and special treatment needed, if necessary
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Poisons A and B
SECTION 5: Firefighting measures
Suitable extinguishing media
Do not use a direct water stream; it may spread the fire. Use water fog or fine spray, carbon-dioxide or dry-chemical extinguishers, or foam. Water fog applied gently may be used as a blanket to extinguish the fire.
Specific hazards arising from the chemical
no data available
Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.
Environmental precautions
Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up
If a large spill does occur, contain spilled material if possible. Pump the contained material into suitable and properly labeled containers using appropriate safety equipment.
SECTION 7: Handling and storage
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store PPh in carbon steel, stainless steel, or phenolic-lined steel drums. Do not store in aluminum, copper, galvanized iron, or galvanized steel.
SECTION 8: Exposure controls/personal protection
Control parameters
no data available
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Liquid.
-
Colour：
Clear, colourless.
-
Odour：
Mild odor
-
Melting point/freezing point：
11 °C.
-
Boiling point or initial boiling point and boiling range：
241.2 °C. Atm. press.:1 013.25 hPa.
-
Flammability：
no data available
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
Ca. 239 °F. Atm. press.:Ca. 760 mm Hg.
-
Auto-ignition temperature：
Ca. 480 °C. Atm. press.:Ca. 1 013 hPa.
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
dynamic viscosity (in mPa s) = 22.7. Temperature:25.0°C.
-
Solubility：
In water, 15.1 g/L at 20 deg C
-
Partition coefficient n-octanol/water：
log Pow = 1.41. Temperature:24.1 °C.;log Pow = 1.48. Temperature:24.1 °C.;log Pow = 1.49. Temperature:24.1 °C.
-
Vapour pressure：
0.01 hPa. Temperature:20 °C.
-
Density and/or relative density：
1.06. Temperature:20 °C.
-
Relative vapour density：
5.27 (Air = 1)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
no data available
Chemical stability
PPh is thermally stable at typical use temperatures...PPh can decompose at elevated temperatures.
Possibility of hazardous reactions
no data available
Conditions to avoid
no data available
Incompatible materials
PPh is incompatible with strong acids, strong bases, and strong oxidizers and contact should be avoided.
Hazardous decomposition products
Decomposition products depend upon the temperature, air supply, and the presence of other materials, but can include aldehydes, ketones, organic acids, and other compounds.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 2830 mg/kg
- Inhalation: LC50 Rat inhalation (4 hr) > 5400 mg/cu m
- Dermal: LD50 - rat (male/female) - > 2 000 mg/kg bw.
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 - Pimephales promelas - 280 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: LC50 - Daphnia magna - 471 mg/L - 24 h.
- Toxicity to algae: EC50 - Desmodesmus subspicatus (previous name: Scenedesmus subspicatus) - > 100 mg/L - 72 h.
- Toxicity to microorganisms: EC20 - activated sludge, domestic - ca. 700 mg/L - 30 min. Remarks:Respiration rate.
Persistence and degradability
AEROBIC: In aerobic soil biodegradation studies using two sandy loam soils and one sandy soil collected in Michigan, propylene glycol phenyl ether had an initial 50% removal rate of <1 day in the sandy loam soils and <5 days in the sandy soil at initial concentrations of 1.4-1.5 ppm(1); at initial concentrations of 107-108 ppm, 50% removal was <5 days in the sandy loam soils and <23 days in the sandy soil(1); maximum percentage of 14-CO2 evolved ranged from 31-66%(1); negligible removal occurred in sterile soil controls(1). Using the three Michigan soils, after 2 months under anaerobic conditions (at a nominal concentration of 10 ppm), a 16% reduction in propylene glycol phenyl ether was observed in sodium acetate supplemented microcosms whereas, in the sterile controls, a 7% reduction was observed(2). Using OECD Guideline 301F (Manometric Respirometry Test) with a sediment and activated sludge inoculum, propylene glycol phenyl ether had a 60% degradation in 9.8 days and 72% degradation in 28 days which met the criteria for being classified as readily biodegradable(2). 20-Day BODs of 42% and 50% have been reported for propylene glycol phenyl ether using a municipal seed and an industrial seed, respectively, but additional test conditions were unavailable(2). Using a mixture of phenoxypropanols (85% propylene glycol phenyl ether and 15% 2-phenoxy-1-propanol) at an initial concentration of 420-500 mg/L with the Zahns-Wellens test in accordance with OECD guidelines, approximately 88% of the mixture biodegraded in 18 days of incubation using non-adapted microorganisms from a sewage plant as inoculum(3); using adapted sewage plant microorganism, approximately 85% of the mixture biodegraded in 11 days(3); using microorganisms isolated from the Elbe River, approximately 90% of the mixture biodegraded in 21 days(3).
Bioaccumulative potential
An estimated BCF of 2.5 was calculated in fish for propylene glycol phenyl ether(SRC), using a log Kow of 1.50(1) and a regression-derived equation(2). According to a classification scheme(2), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
Using a structure estimation method based on molecular connectivity indices(1), the Koc of propylene glycol phenyl ether can be estimated to be 23(SRC). According to a classification scheme(2), this estimated Koc value suggests that propylene glycol phenyl ether is expected to have very high mobility in soil.
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Packing group, if applicable
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/