Acute toxicity - Category 4, Oral
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2
H302 Harmful if swallowed
H411 Toxic to aquatic life with long lasting effects
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P391 Collect spillage.
none
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
no data available
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Refer for medical attention .
Inhalation may cause cyanosis (blue color in lips and under finger nails). Contact with liquid causes local irritation of eyes. Neither ingestion nor contact with skin produces any recognized immediate effects. (USCG, 1999)
Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilation if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary . Monitor for shock and treat if necessary . Anticipate seizures and treat if necessary . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport . Do not use emetics. For ingestion, rinse mouth and administer 5 mg/kg up to 200 mL of water for dilution if the patent can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal . Cover skin burns with dry sterile dressings after decontamination . /Organic bases/Amines and related compounds/
Powder, alcohol-resistant foam, water spray, carbon dioxide.
Special Hazards of Combustion Products: Toxic nitrogen oxides are produced in a fire. (USCG, 1999)
Use water spray, powder, alcohol-resistant foam, carbon dioxide.
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT wash away into sewer. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. Carefully collect remainder. Then store and dispose of according to local regulations.
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT wash away into sewer. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. Carefully collect remainder. Then store and dispose of according to local regulations.
Environmental considerations: Water spill: Use natural barriers or oil spill control booms to limit spill travel. Use natural deep water pockets, excavated lagoons, or sand bag barriers to trap material at bottom. Remove trapped material with suction hoses.
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Dry. Keep in the dark. Well closed.Keep well closed and protected from light.
Component | 1-naphthylamine | |||
---|---|---|---|---|
CAS No. | 134-32-7 | |||
Limit value - Eight hours | Limit value - Short term | |||
ppm | mg/m3 | ppm | mg/m3 | |
Austria | 0,17 | 1 inhalable aerosol | 0,68 | 4 inhalable aerosol |
Germany (AGS) | 0,17 (1) | 1 (1) | 0,68 (1)(2) | 4 (1)(2) |
South Korea | ? | 0,006 | ? | ? |
Remarks | ||||
Austria | TRK value (based on technical feasibility) | |||
Germany (AGS) | (1) Inhalable aerosol and vapour (2) 15 minutes reference period |
no data available
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Wear safety spectacles or eye protection in combination with breathing protection.
Protective gloves. Protective clothing.
Use local exhaust or breathing protection.
no data available
Alpha-naphthylamine is a crystalline solid or a solid dissolved in a liquid. Insoluble in water and denser than water. Contact may slightly irritate skin, eyes and mucous membranes. May be slightly toxic by ingestion. Used to make other chemicals.
Needles from ethanol (aq) or ether
Ammonia-like odor.
50 °C
300.8 °C
Combustible Solid
no data available
157 °C
905° F (NTP, 1992)
no data available
Weak base
no data available
Insoluble in water
log Kow = 2.25
0.00108mmHg at 25°C
1.12
4.93 (NTP, 1992) (Relative to Air)
no data available
NIOSH considers alpha-naphthylamine to be a potential occupational carcinogen.
Decomposes on burning. This produces nitrogen oxides and carbon monoxide. The substance is a weak base.
Oxidizes in air
ALPHA-NAPHTHYLAMINE is incompatible with oxidizing agents. It is also incompatible with nitrous acid. It reduces warm ammoniacal silver nitrate. (NTP, 1992).
no data available
Oxidizes in air.
The substance decomposes on burning producing nitrogen oxides and carbon monoxide.
no data available
no data available
no data available
no data available
Inadequate evidence of carcinogenicity in humans. Inadequate evidence of carcinogenicity in animals. OVERALL EVALUATION: Group 3: The agent is not classifiable as to its carcinogenicity to humans.
no data available
The substance is mildly irritating to the eyes and skin. The substance may cause effects on the blood. This may result in the formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. See Notes.
See Notes.
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly.
AEROBIC: Using activated sludge from both domestic and industrial sources and the Warburg technique, 1-naphthylamine depletion after 6 hrs at 25 deg C was measured to be 80-84% from an initial concn of 20 ppm(1). 1-Naphthylamine, at a concn of 500 ppm, was extensively oxidized by an aniline-acclimated activated sludge after 19 hrs in a Warburg respirometer(2). Over a 20-day period, no biodegradation of 200 ppm 1-naphthylamine as a sole carbon source was observed in a batch system containing an adapted activated sludge(3). 1-Naphthylamine at 500 ppm was found to inhibit oxygen uptake in a Warburg respirometer containing a municipal activated sludge(4). At 1000 ppm, 1-naphthylamine was toxic to an activated sludge(5). 1-Naphthylamine degradation in six different soils after 308 days of incubation at 23 deg C varied from 16.6-30.7% as measured by radio-labelled carbon dioxide evolution(6). Comparison of carbon dioxide evolution in sterilized (via gamma radiation) versus unsterilized soil suggested that the degradation was predominantly microbial in nature(6). Approximately 16, 28 and 33% of added 1-naphthylamine degraded in Russell soil at temperatures of 12, 23 and 30 deg C, respectively, indicating the effect of temperature on microbial degradation(6).
An estimated BCF of 11 was calculated for 1-naphthylamine(SRC), using a log Kow of 2.25(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC), provided the compound is not altered physically or chemically once released into the environment.
Using a batch equilibrium technique, 1-naphthylamine Koc values of 2,688 and 3,173 were determined for two sandy-silt soils and a Koc value of 3,777 was determined for a silty-clay soil(1). According to a classification scheme(2), this estimated Koc value suggests that 1-naphthylamine is expected to have low mobility in soil. Results of a batch equilibrium study with various soils indicated that 1-naphthylamine binds to soil in two phases with an initial rapid and reversible equilibrium established between the amine and the inorganic and organic components of soil followed subsequently by a strong association with the humic fraction of soil via covalent binding(3,4). In laboratory study, 1-naphthyalmine was found to have a relatively moderate tendency to adsorb to lignite coal in subsurface areas where it may be present as a contaminant from coal-gasification plants(5).
no data available
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
ADR/RID: UN2077 (For reference only, please check.)
IMDG: UN2077 (For reference only, please check.)
IATA: UN2077 (For reference only, please check.)
ADR/RID: alpha-NAPHTHYLAMINE (For reference only, please check.)
IMDG: alpha-NAPHTHYLAMINE (For reference only, please check.)
IATA: alpha-NAPHTHYLAMINE (For reference only, please check.)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
ADR/RID: III (For reference only, please check.)
IMDG: III (For reference only, please check.)
IATA: III (For reference only, please check.)
ADR/RID: Yes
IMDG: Yes
IATA: Yes
no data available
no data available
Depending on the degree of exposure, periodic medical examination is indicated.Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.Bladder cancers reported after occupational exposure to 1-naphthylamine may be due to contamination with 2-naphthylamine which is a human carcinogen.