Oleanolic Acid
| Price | USD10.00 |
| Packge | 1kg |
- Min. Order:1kg
- Supply Ability:10000
- Time:2022-07-26
Product Details
- Product NameOleanolic Acid
- CAS No.508-02-1
- EINECS No.208-081-6
- MFC30H48O3
- MW456.7
- InChIKeyMIJYXULNPSFWEK-FRJBHDQENA-N
- Appearanceneatlight yellow
- storage temp. 2-8°C
- Melting point >300 °C (lit.)
- Boiling point 502.79°C (rough estimate)
- density 1.0261 (rough estimate)
Product Name: Oleanolic Acid
Synonym: Oleanol
Appearance: White fine powder
Botanical Source: Hemsleya chinensis cogn.
Description:
Oleanolic acid is a naturally occurring triterpenoid, widely distributed in food and medicinal plants.
Oleanolic acid has been marketed in China as an oral drug for human liver disorders. The mechanism of hepatoprotection by these two compounds may involve the inhibition of toxicant activation and the enhancement of the body defense systems. Oleanolic acid and ursolic acid have also been long-recognized to have anti-inflammatory and anti-hyperlipidemic properties in laboratory animals, and more research is warranted to develop a therapy for patients. In addition, oleanolic acid has the effects of correcting protein metabolism disorders, anti-inflammatory, strong heart, and diuresis, increasing white blood cells, lowering blood sugar and promoting immune function, and inhibiting the growth of S-180 tumor.
Application:
1. Reduce liver damage: Oleanolic acid for the tricyclic triterpenoid compounds, carbon tetrachloride-induced acute and chronic liver injury in rats have a significant protective effect. After treatment, the enlarged mitochondria and the expansion of the rough endoplasmic reticulum are restored. But also can make acute and chronic liver injury in the liver cell balloon degeneration, necrosis and inflammatory response was significantly reduced. Increased triglyceride accumulation in the liver, increased glycogen content.
2. Decreased serum alanine aminotransferase activity: oleanolic acid on acute, chronic hepatitis and cirrhosis animals have significant role in reducing enzymes.
3. Reduces serum r-globulin and is consistent with the reduction of inflammatory response in the liver seen by histology.
4. Promote the regeneration of liver cells: oleanolic acid can promote the residual liver of the nuclear division of the number increased significantly, higher than the control group, suggesting that the role of promoting cell regeneration.
5. Reduce the level of tetracycline in the brain homogenate of cirrhotic rats: due to the significant decrease in the level of tyrosine in the brain homogenate, it can inhibit the formation of pseudo neurotransmitters, so it is beneficial to the prevention and treatment of hepatic encephalopathy.
6. Inhibition of liver fibrosis: oleanolic acid treatment of liver fibrosis in rats, severe liver fibrosis and significantly reduced, decreased liver collagen content, suggesting that the role of prevention and treatment of liver cirrhosis.
7. Oleanolic acid has a significant inhibitory effect on mouse mononuclear phagocytic cell system, macrophage phagocytosis and experimental arthritis, but has an effect on both humoral immune function and antigen-binding cells. Enhance immunity and inhibit S180 tumor growth.
8. On the damage of chromosomes have a protective effect on experimental atherosclerosis have a preventive effect, but also to correct protein metabolism disorders.
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Company Profile Introduction
Changsha Staherb Natural Ingredients Co., Ltd., a good supplier of professional herb extracts, especially those with high purity and standardized production process. Our company devotes to supply high quality products and services to customers in R&D and production fields of health products, cosmetics, feed additives and biopesticides.
With cordial and professional R&D, sales and after-sales service groups, Staherb has potent capabilities both in R&D and production. The company persists in high investment on R&D of active ingredients of plants and promotes innovation on demands of customers. Upon constant R&D and tracing of new technologies and new products, Staherb makes effective cooperation with famous research institutes, such as CAS Kunming Institute of Botany, State Key Lab of Hunan Forest Products and Chemical Engineering, Hunan Agricultural University and so on.
Now the main products of Staherb are standardized high purity plant extracts, including Epimedium (10-98%), Euccomia Bark Extract (5-95%), Amygdalin (50-98%), Ursolic acid (25-98%) and Corosolic acid (1-98%). In order to meet customers’ research needs, our company also provides over 600 plant extracts, most of which are high-purity monomer plant compounds and reference substance. And some products can be supplied with milligram-scale, kilogram-scale or even to ton-scale. In addition, based upon the powerful R&D capability, Staherb can provide both products customization services and R&D outsourcing services according to customers’ specific requirements, so that to meet their continual innovation needs in the fields of natural products’ discovery and production.
Staherb endeavors to accelerate the response rate of supply chain as well as improve the service superiority upon customers’ continual innovation needs. It also devotions to establish good partnerships with customers and to construct a safe development model which is forward-looking, reciprocal and coexisting, thus to create long-term value for customers through division and cooperation as well as complementation.
- Since:2010-04-06
- Address: No. 186, Lugu Valley Garden Road, High-tech Dev. Zone, Changsha, Hunan, China