99% Bulk Ribociclib Lee011 Rebosini Powder CAS 1256963-02-6
Price | USD10.00 | USD15.00 | USD20.00 |
Packge | 1kg | 1kg | 1kg |
- Min. Order:1kg
- Supply Ability:20tons
- Time:2022-07-07
Product Details
- Product NameLEE011/ Ribociclib
- CAS No.1256963-02-6
- MFC22H29ClN8
- MW440.97
- AppearanceSolidBeige
- Boiling point 679.3±65.0 °C(Predicted)
- density 1.31±0.1 g/cm3(Predicted)
- Melting point >180°C (dec.)
- storage temp. -20°C Freezer
Basic Info.
Product Description
Product Name: LEE011
Synonyms: Rebosini;LEE011;CDK4/6 inhibitor;CDK4 inhibitor;CDK4-IN-1;CS-842;4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-N-(5-(4-(dimethylamino)piperidin-1-yl)pyridin-2-yl)pyrimidin-2-amine;CDK 4/6 Inhibitor, >=98%
CAS: 1256963-02-6
MF: C22H29ClN8
MW: 440.97
Appearance: White Powder
Shipping: Safety and fast, guarantee delivery
LEE011 (also known as ribociclib) is a CDK4/6 inhibitor. It has been recently approved by FDA (brand name: Kisqali®) to be combined with an aromatase inhibitor for initial endocrine-based therapy for treatment of postmenopausal women with hormone receptor positive, human epidermal growth factor receptor-2 negative (HR+/HER2-) advanced or metastatic breast cancer. It inhibits the growth of tumor cells by arresting the cells at the G1 checkpoint, which prevents the tumor cells from proliferating. In the phase III trial, it demonstrating statistically significant improvement in progression-free survival (PFS) compared to letrozole alone at the first pre-planned interim analysis.
Company Profile Introduction
Recommended supplier
-
VIP1年
- Vachichem
- Ribociclib 98%
- Inquiry
- 2024-01-16
-
VIP1年
- cdymax
- Ribociclib 97%
- Inquiry
- 2023-11-27
- Since:2022-03-18
- Address: Room 601, Unit 1, Building 1, 188 Xinhuali, North Xinhua Road, Xiangdu District, Xingtai city, Hebei