CAS 84057-84-1 Lamotrigine Anticonvulsant Drug

Product Info:
Lamotrigine(BW430C) is a novel anticonvulsant drug for inhibition of 5-HT and sodium channelTarget: Sodium ChannelLamotrigine stabilises presynaptic neuronal membranes by blockade of voltage-dependent sodium channels, thus preventing the release of excitatory neurotransmitters, particularly glutamate and aspartate [1]. In rat cerebral cortex tissue incubated with veratrine 10 mg/L, lamotrigine is twice as potent in inhibiting the release of glutamate and aspartate (ED 50 = 5.38 mg/L for each) than the release of GABA (ED50 = 11.2 mg/L), and is much less potent in inhibiting acetylcholine release (ED50 = 25.6 mg/L) when cortical slices is exposed to veratrine 75 mg/L. Basal glutamate release is unaffected [2]. Lamotrigine inhibits high-frequency sustained repetitive firing of sodium-dependent action potentials, indicating a direct effect on voltage-activated sodium channels [3]. Lamotrigine (Lamictal), a phenyltriazine derivative, is a well established anticonvulsant agent that has shown efficacy in the prevention of mood episodes in adult patients with bipolar I disorder. lamotrigine significantly delayed time to intervention for a depressive episode and showed limited efficacy in delaying time to intervention for a manic/hypomanic episode, compared with placebo. Lamotrigine is generally well tolerated.
General info CAS 84057-84-1 lamotrigine anticonvulsant drug

Synonyms:

1. Quality
Our products meet MSDS safe standard and we have ISO and other certificate so yan can get high quality products from our company.
2. Price
We are the company which is the joint of trade and industry so we cao provide the competitive price and high quality product.
3.Packing
Generally, the package is 25 kg.
But,we can do according to the customers' request.
4.Transport
The products can be transported  by Courier, by air or by sea  
5.Service
We offer specialized logistic service including export declaration,customs clearance and every detail during shipment,this makes us able to offer you one-stop service from the order to the products transported to your hand.

      Our company provides chemical raw materials, chemical products, pharmaceutical intermediates, veterinary intermediates, dye intermediates, pigments, cosmetic raw materials, chemical reagents and PVC particles to meet your various needs.
      With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements.
Consistent Quality
      Our plant has strict quality control in each manufacturing process. Guaranteed.Meanwhile all the materials are tested before each shipment in our laboratory to double confirm the quality.
Most competitive pricing
      Our company is committed to the production and development of titanium dioxide, we always offer the most competitive pricing to customers to help lower their cost in application.
Shortest delivery time
      90% of orders are shipped within 7-10 days after receipt of the prepayment or Western union
Respond in 24 hours to inquiry, feedback or other requirements
     Our experienced staff is dedicated to answer all of your inquires, feedback or other requirements in 24 hours.
     We welcome you to contact us for more information and look forward to working with you