6-amino-4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-7-ethoxyquinoline-3-carbonitrile TDS msds coa

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Product Name6-amino-4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-7-ethoxyquinoline-3-carbonitrile TDS msds coa
CAS No.848139-78-6
EINECS No.810-025-6
MFC24H20ClN5O2
MW445.9
AppearanceSolidOff-White to Pale Yellow
Boiling point 649.8±55.0 °C(Predicted)
density 1.39±0.1 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
Melting point 236-238oC (dec.)

6-amino-4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-7-ethoxyquinoline-3-carbonitrile TDS msds coa

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6-amino-4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-7-ethoxyquinoline-3-carbonitrile 848139-78-6 Factory PRICE IN STOCK COA CAS 848139-78-6

4-[4-[(2-Pyridyl)methoxy]-3-chloroanilino]-6-amino-3-cyano-7-ethoxyquinoline

848139-78-6 CAS 848139-78-6 highly quality and immedaite delivery 4-aminodiphenyl ether

6-amino-4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-7-ethoxyquinoline-3-carbonitrile COA TDS price MSDS

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6-amino-4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-7-ethoxyquinoline-3-carbonitrile 848139-78-6

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Product Name: 6-amino-4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-7-ethoxyquinoline-3-carbonitrile

Synonyms: 6-amino-4-(3-chloro-4-(pyridin-2-yloxy)phenylamino)-7-ethoxyquinoline-3-carbonitrile;6-amino-4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-7-ethoxyquinoline-3-carbonitrile;6-AMino-4-((3-chloro-4-(pyridin-2-ylMethoxy)phenyl)aMino)-7-ethoxyquinoline-3-carbonitrile (Hydrochloride);3-Quinolinecarbonitrile, 6-aMino-4-[[3-chloro-4-(2-pyridinylMethoxy)phenyl]aMino]-7-ethoxy-;4-[4-[(2-Pyridyl)methoxy]-3-chloroanilino]-6-amino-3-cyano-7-ethoxyquinoline;6-Amino-4-[3-chloro-4-[(2-pyridinyl)methoxy]anilino]-3-cyano-7-ethoxyquinoline;6-amino-4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-ethoxy-quinoline-3-carbonitrile;Neratinib Intermediate3

CAS: 848139-78-6

MF: C24H20ClN5O2

MW: 446

EINECS: 810-025-6

6-Amino-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxyquinoline-3-carbonitrile, is used in the synthetic preparation of aminopropanamides which is used in irreversible inhibition of epidermal growth factor receptor (EGFR) for potential use in cancer therapy.

Chemical Name 6-amino-4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-7-ethoxyquinoline-3-carbonitrile

Synonyms

QUI129;

CAS No. 848139-78-6

Molecular Formula C24H20ClN5O2

Molecular Weight 445.90100

Solubility Insuluble (1.6E-4 g/L) (25 ºC), Calc.*

Density 1.39±0.1 g/cm3 (20 ºC 760 Torr), Calc.*

6-amino-4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-7-ethoxyquinoline-3-carbonitrile Chemical Properties

Boiling point 649.8±55.0 °C(Predicted)

density 1.39±0.1 g/cm3(Predicted)

pka 5.09±0.50(Predicted)

Safety Information

MSDS Information

6-amino-4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-7-ethoxyquinoline-3-carbonitrile Usage And Synthesis

6-amino-4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-7-ethoxyquinoline-3-carbonitrile Preparation Products And Raw materials

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Company Profile Introduction

Over 30 years experience in the chemical industry, Chemwill Asia co.,Ltd is one of the leading manufacturer of Organic compounds in CHINA. We own GMP licence as well as ISO certificate paper. CHemwill employs over 165 peoples including professional technical experts and professional-trained workers. The sales volume of our company in 2018 is over 8.5 million dollars.

Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Active pharmaceutical ingredients(APIs), Veterinary, Indole derivatives, Aromatics, Fluorine, Boronic acids, organocatalysts, chiral building blocks, heterocyclic compounds. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.

Our advantageous business including:

- Intermediate using for Pharmaceuticals

- Fluorine, boronic acids, unnatural amino acids, cross linkers,chiral building blocks

- Intermediate using for advanced performance materials

- Monomer & polymers, high performance, photosensitive and specialty chemicals

- Electro chemical materials(Lithium Battery, Photoresist, semiconductor, IT-related chemicals)

* Custom synthesis from the laboratory scale to commercial production.

* Contract research, custom manufacturing and contract-manufacture

Our R&D team masters core technology for process-design of target building block as well as Tailor-made fine chemicals. Our manufactory specialised in extreme temperature conditions (-100ºC to +300ºC), hydrogenations reaction under high pressure, suzuki coupling reaction, photochemical reaction, Mitsunobu reactions, enantioselective reactions and asymmetric synthesis.

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6-amino-4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-7-ethoxyquinoline-3-carbonitrile TDS msds coa

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Chemwill Asia Co.,Ltd.