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WM 20-3
| Price | USD1.00 |
| Packge | 1KG |
- Min. Order:100KG
- Supply Ability:1000kg
- Time:2020-03-12
Product Details
- Product Name4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinaminedihydrochloride
- CAS No.950912-80-8
- MFC19H20FN5.2HCl
- MW410
- Appearancepowderwhite to beige
- storage temp. 2-8°C
- Melting point >178°C (dec.)
4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinaminedihydrochloride Basic information
Product Name: 4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinaminedihydrochloride
Synonyms: 4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinamine hydrochloride;PF670462/ PF-670462;2-PyriMidinaMine, 4-[1-cyclohexyl-4-(4-fluorophenyl)-1H-iMidazol-5-yl]-, hydrochloride (1:2);4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinamine hydrochloride PF670462;4-[3-Cyclohexyl-5-(4-fluoro-phenyl)-3H-imidazol-4-yl]-pyrimidin-2-ylamine dihydrochloride;PF 670462, >=98%;4-[1-cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]pyrimidin-2-amine dihydrochloride;Casein Kinase I Inhibitor II, PF-670462 - CAS 950912-80-8 - Calbiochem
CAS: 950912-80-8
MF: C19H20FN5.2HCl
MW: 410
EINECS:
Product Categories: Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Protein Kinase Inhibitors and Activators;Inhibitors
Mol File: 950912-80-8.mol
4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinaminedihydrochloride Structure
4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinaminedihydrochloride Chemical Properties
storage temp. Desiccate at RT
solubility H2O: soluble2mg/mL, clear (warmed)
form powder
color white to beige
InChIKey PSNKGVAXBSAHCH-UHFFFAOYSA-N
Safety Information
WGK Germany 3
MSDS Information
4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinaminedihydrochloride Usage And Synthesis
Uses PF 670462 is a potent and selective casein kinase 1ε (CK1ε) and CK1δ inhibitor. PF 670462 has been shown to inhibit PER protein nuclear translocation causing phase shifts in circadian rhythms. PF 670462 attenuates methamphetamine-stimulated locomotion in vivo.
Definition ChEBI: A hydrochloride salt resulting from the formal reaction of 3-[(3-chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine with 2 mol eq. of hydrogen chloride. It is a selectiv inhibitor of the delta- and epsilon-isoforms of casein kinase 1 (CK1delta and CK1epsilon).
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
Recommended supplier
- Since:2014-12-17
- Address: Room 702, Floor 7, Building 10, National University Science Park, High-Tech Zone, Zhengzhou City, H
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