Goserelin

Product Name: Goserelin

Synonyms: GOSERELIN ACETATE SALT;(D-SER(TBU)6,AZAGLY10)-GONADOTROPIN-RELEASING HORMONE ACETATE SALT;(D-SER(TBU)6,AZAGLY10)-LHRH ACETATE SALT;(D-SER(TBU)6,AZAGLY10)-LUTEINIZING HORMONE-RELEASING FACTOR ACETATE SALT;(D-SER(TBU)6,AZAGLY10)-LUTEINIZING HORMONE-RELEASING HORMONE ACETATE SALT;PYR-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-AZAGLY-NH2 ACETATE SALT;Goserlin;Goserelin-d7

CAS: 65807-02-5

MF: C61H88N18O16

MW: 1329.46

EINECS:

Product Categories: Pepetides;peptides;hormones

Mol File: 65807-02-5.mol

Goserelin Structure

Goserelin Chemical Properties

density 1.50±0.1 g/cm3(Predicted)

storage temp. −20°C

solubility H2O: 20 mg/mL, clear, colorless

form white powder

pka 9.82±0.15(Predicted)

Safety Information

Safety Statements 22-24/25

WGK Germany 3

Hazardous Substances Data 65807-02-5(Hazardous Substances Data)

MSDS Information

Provider Language

SigmaAldrich English

Goserelin Usage And Synthesis

Description Goserelin is an analog of luteinizing hormone-releasing hormone (LHRH) useful in the treatment of malignancies responsive to hormonal manipulation. Administered parenterally in a biodegradable depot, goserelin is reportedly as effective as orchidectomy and oophorectomy in patients with advanced prostate carcinoma and pre-menopausal breast cancer.

Chemical Properties White or almost white powder.

Originator ICI (United Kingdom)

Uses Labeled Goserelin, intended for use as an internal standard for the quantification of Goserelin by GC- or LC-mass spectrometry.

Brand name Zoladex (Zeneca).