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HomecompanyTaccalonolide A
Taccalonolide A
Taccalonolide A
Taccalonolide A
Taccalonolide A
Taccalonolide A
Taccalonolide A

Taccalonolide A

Price USD9.80
Packge 1KG
  • Min. Order:1KG
  • Supply Ability:20 tons
  • Time:2020-02-07

Product Details

  • Product NameTaccalonolide A
  • CAS No.108885-68-3
  • MFC36H46O14
  • MW702.74
  • AppearanceSolidWhite to off-white
  • density 1.41±0.1 g/cm3 (20 ºC 760 Torr)
  • Boiling point 776.8±60.0 °C(Predicted)
  • storage temp. Store at -20°C

Jessie 785

Contact: jessie@coreychem.com

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[Product Specification】

Names

Name
Taccalonolide A
Synonym

 Taccalonolide A Biological Activity

Description
Taccalonolide A is a microtubule stabilizer, which is a steroid isolated from Tacca chantrieri, with cytotoxic and antimalarial activities[1][2]. Taccalonolide A causes G2-M accumulation, Bcl-2 phosphorylation and initiation of apoptosis[1]. Taccalonolide A is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug resistance protein 7 (MRP7), with an IC50 of 622 nM for SK-OV-3 cells[3].
Target

microtubule[1]

 Chemical & Physical Properties

Density
1.4±0.1 g/cm3
Boiling Point
776.8±60.0 °C at 760 mmHg
Molecular Formula
C36H46O14
Molecular Weight
702.742
Flash Point
237.8±26.4 °C
Exact Mass
702.288757
PSA
201.56000
LogP
2.49
Vapour Pressure
0.0±6.1 mmHg at 25°C
Index of Refraction
1.590
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;
  • Since:2014-12-17
  • Address: Room 702, Floor 7, Building 10, National University Science Park, High-Tech Zone, Zhengzhou City, H
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